Results 141 to 150 of about 30,287 (286)

Screening for differentially expressed circRNA between Kashin–Beck disease and osteoarthritis patients based on circRNA chips

, 2020
Objective: This research aims to explore differentially expressed circRNA between OA and KBD and potential diagnostic biomarkers.Methods: Total RNA was extracted from 5 pairs of KBD and OA knee joint cartilage specimens, and the expression of circRNAs ...
Wu, Cuiyan,, Guo, Xiong,, Lammi, Mikko J.,, Zhang, Yanan,, Yang, Yimin,, Ren, Zhiwei,, Wang, Ying,   +6 more
core   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

Biogenesis, Functions, and Role of CircRNAs in Lung Cancer

Cancer Management and Research, 2021
Huanhuan Dong,* Junliang Zhou,* Yue Cheng, Meiqi Wang, Shuqing Wang, Hui Xu Department of Clinical Laboratory, Harbin Medical University Cancer Hospital, Harbin, 150081, People’s Republic of China*These authors contributed equally to this ...
Dong H, Zhou J, Cheng Y, Wang M, Wang S, Xu H   +5 more
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HNRNPD regulates the biogenesis of circRNAs and the ratio of mRNAs to circRNAs for a set of genes

RNA Biology
Exonic circular RNAs (ecircRNAs) in animal cells are generated by backsplicing, and the biogenesis of ecircRNAs is regulated by an array of RNA binding proteins (RBPs). HNRNPD is a heterogeneous nuclear ribonucleoprotein family member with both cytoplasmic and nuclear roles, and whether HNRNPD regulates the biogenesis of circRNAs remains unknown.
Shuhui Chang, Yucong Wang, Xiaolin Wang, Hanyuan Liu, Tao Zhang, Yangge Zheng, Xueren Wang, Ge Shan, Liang Chen   +8 more
openaire   +3 more sources

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Dysregulation of circRNA-0076906 and circRNA-0134944 is Correlated with Susceptibility to Osteoporosis and Osteoporotic Fracture in Postmenopausal Females from the Chinese Han Population

Pharmacogenomics and Personalized Medicine, 2023
Weijie Yang,* Wei Zhang,* Fengqian Li, Ning Xu, Ping Sun Department of Orthopedics, Shanghai Eighth People’s Hospital, Shanghai, 200235, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ping Sun ...
Yang W, Zhang W, Li F, Xu N, Sun P
doaj  

The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity

The Journal of Physiology, EarlyView.
Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas, Debbie J. Otto, Daniel Stratton, Katja Rietdorf, Daniel M. Johnson, Calum J. McMullen   +5 more
wiley   +1 more source

Hierarchical clustering of circRNA expression data.

, 2017
Hierarchical clustering of the circRNA expression data based on ‘All Targets Value’–which arranges the samples into groups based on their expression levels–revealed a distinguishable circRNA expression profiling among samples.
Lixin Shi (577302), Qiao Zhang (138583), Hui Ye (164331), Nianchun Peng (3833131), Ying Hu (14950), Nanpeng Wang (3833128)   +5 more
core   +1 more source

Expression Profile of circRNA in Lung Cancer Cells Infected with Staphylococcus aureus

Thoracic Research and Practice
INTRODUCTION: Lung cancer is one of the main causes of cancer -related deaths on a global scale and ranks first with approximately 1.8 million deaths according to 2022 data.1 Tumor formation is shaped not only by genetic and epigenetic changes, but also ...
Deniz Ece, Cagla Ozdenizer, Can Muftuoglu, Ufuk Mert, Ayse Caner   +4 more
doaj   +1 more source

Recent Update on the Role of Circular RNAs in Hepatocellular Carcinoma

Journal of Hepatocellular Carcinoma, 2021
Abdullah Ely, Kristie Bloom, Mohube Betty Maepa, Patrick Arbuthnot Wits/SAMRC Antiviral Gene Therapy Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South AfricaCorrespondence: Patrick ...
Ely A, Bloom K, Maepa MB, Arbuthnot P
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