Results 111 to 120 of about 30,287 (286)

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Identification of Three Potential circRNA Biomarkers of Polycystic Ovary Syndrome by Bioinformatics Analysis and Validation

International Journal of General Medicine, 2021
Pengyu Huang,* Shengrong Du,* Yunhong Lin,* Zhiqing Huang, Haiyan Li, Gangxin Chen, Suzhu Chen, Qingfen Chen, Lincui Da, Hang Shi, Wei Wei, Lei Yang, Yan Sun, Beihong Zheng Reproductive Medicine Center, Fujian Maternity and Child Health ...
Huang P, Du S, Lin Y, Huang Z, Li H, Chen G, Chen S, Chen Q, Da L, Shi H, Wei W, Yang L, Sun Y, Zheng B   +13 more
doaj  

circRNA-miRNA-hub gene subnetwork.

, 2021
The network consists of 24circRNAs, 3 miRNAs and 10 mRNAs. The rectangles indicate miRNAs, the diamonds indicate circRNAs, and the ellipses indicate mRNAs. The red nodes represent increased expression, and the blue nodes represent decreased expression.
Tao-Lin Xia (11790741), Liang Luo (425058), Lei-Lei Zhang (4348597), Wen Tao (848995), Liao-Yuan Li (2328004)   +4 more
core   +1 more source

Genomics and epigenomics of tissue repair: Implications for personalized medicine

Precision Medical Sciences, EarlyView.
Genomic and epigenomic mechanisms govern tissue repair and regeneration through dynamic regulation of inflammation, cell fate, and extracellular matrix remodeling. The integration of multi‐omics, artificial intelligence, and precision regenerative therapies enables biomarker‐driven, personalized approaches to enhance healing and minimize fibrosis ...
Jharna Medhi, Chandrashekar Thalluri, Sarad Pawar Naik Bukke, Piyali Dey, Mallikarjun Vasam, Ananda Kumar Chettupalli, Swetha Kumari Koduru, Gali Avinash Kumar   +7 more
wiley   +1 more source

Invention of circRNA promoting RNA to specifically promote circRNA production

Nucleic Acids Research
Abstract CircRNA, an essential RNA molecule involved in various biological functions and diseases, often exhibits decreased expression in tumor tissues, playing a role as a tumor suppressor, and suggesting therapeutic potential for cancer. However, current methods for promoting circRNA production are limited.
Zhilin He, Haofei Ji, Bei Xia, Xiuen Cao, Ying Huang, Qubo Zhu   +5 more
openaire   +2 more sources

Therapeutic Properties and Underlying Mechanisms of Traditional Chinese Medicine in Managing Rheumatoid Arthritis: An Integrative Review of Clinical and Molecular Findings

Phytotherapy Research, EarlyView.
The translational research framework integrating TCM for RA. The figure outlines a stepwise framework for the modernization and clinical translation of TCM in RA. Part 1 highlights the inheritance and development of TCM theory, including classical medical texts, traditional herbal knowledge, and syndrome differentiation–based treatment principles. Part
Jianting Wen, Jian Liu, Lei Wan, Fanfan Wang, Yang Li   +4 more
wiley   +1 more source

GO enrichment analysis of DE circRNAs and comparisons between circRNA expression patterns and their circRNA-host genes.

, 2020
(A) GO enrichment analysis of circRNA-host genes of DE circRNAs in response to LP stress. The red and green boxes highlight the gene clusters involved in response to abiotic stress and LP stress, respectively.
Kaiye Yu (5690612), Haiyan Lü (5690600), Xiangqian Zhang (3749950), Chongyuan Sun (8339037), Xiaoqian Liu (154284), Dan Zhang (51283), Lingling Lv (5690615), Jinyu Zhang (310913), Huanqing Xu (8339040), Xiaohui He (1847254)   +9 more
core   +1 more source

Current Advances of Treatments, Therapeutic Targets, Biomarkers, Novel Drugs, and Machine Learning for Hypopharyngeal Squamous Cell Carcinoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Hypopharyngeal squamous cell carcinoma (HSCC) is an aggressive subtype of head and neck squamous cell carcinoma with insidious onset, early metastasis, and dismal prognosis. Conventional multimodal therapy achieves limited survival benefit, highlighting an urgent need for refined precision strategies.
Ce Li, Rui Guan, Rui‐Jie Jiao, Zhi‐Jie Bi, Yang Fu, Yin Wang, Chen‐Yang Xu, Ye Qian, Ran Wei, Sheng‐Da Cao, Wen‐Ming Li, Dong‐Min Wei, Da‐Peng Lei   +12 more
wiley   +1 more source

Synergistic Immunoregulation: harnessing CircRNAs and PiRNAs to Amplify PD-1/PD-L1 Inhibition Therapy

International Journal of Nanomedicine
Rui Han,1,2 Xiwu Rao,3 Huiling Zhou,4 Lingeng Lu5– 7 1Department of Chinese Medicine Oncology, The First Affiliated Hospital of Naval Medical University, Shanghai, People’s Republic of China; 2Department of Chinese Medicine, Naval Medical University ...
Han R, Rao X, Zhou H, Lu L
doaj  

Double matrix completion for circRNA-disease association prediction

, 2021
Background Circular RNAs (circRNAs) are a class of single-stranded RNA molecules with a closed-loop structure. A growing body of research has shown that circRNAs are closely related to the development of diseases. Because biological experiments to verify
Chun-Hou Zheng, Pi-Jing Wei, Zong-Lan Zuo, Rui-Fen Cao, Jun-Feng Xia   +4 more
core   +1 more source