Results 111 to 120 of about 34,260 (269)

Up-Regulation of circRNA hsa_circ_0003074 Expression is a Reliable Diagnostic and Prognostic Biomarker in Patients with Osteosarcoma

open access: yesCancer Management and Research, 2020
Saiyun Lei,1 Lei Xiang2 1Department of Joint Surgical, The Second Affiliated Hospital of University of South China, Hengyang 421001, People’s Republic of China; 2Department of Traumatic Orthopedics, Affiliated Nanhua Hospital, University of South ...
Lei S, Xiang L
doaj  

Integrated Analysis of Altered lncRNA, circRNA, microRNA, and mRNA Expression in Hepatocellular Carcinoma Carrying TERT Promoter Mutations

open access: yesJournal of Hepatocellular Carcinoma, 2022
Haibin Zhang,1 Xiaolu Zhang,1 Jingya Yu2 1Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, People’s Republic of China; 2Department of Diagnostics ...
Zhang H, Zhang X, Yu J
doaj  

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

open access: yesInterdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi   +6 more
wiley   +1 more source

The Biogenesis, Functions, and Roles of circRNAs in Bladder Cancer

open access: yesCancer Management and Research, 2020
Changjiu Li,1,* Xian Fu,2,* Huadong He,1 Chao Chen,2 Yuyong Wang,2 Lugeng He2 1Department of Urology, Affiliated Hangzhou First People’s Hospital, Nanjing Medical University, Hangzhou 310006, Zhejiang Province, People’s Republic of China ...
Li C, Fu X, He H, Chen C, Wang Y, He L
doaj  

Identification of a circRNA/miRNA/mRNA ceRNA Network as a Cell Cycle-Related Regulator for Chronic Sinusitis with Nasal Polyps [Corrigendum]

open access: yesJournal of Inflammation Research, 2022
Sun Q, Liu Z, Xu X, et al. J Inflamm Res. 2022;15:2601–2615. The authors have advised there is an error in Figure 7 on page 2611. The labels “nucleus” and “cytoplasm” in figure part A were mistakenly interchanged and should ...
Sun Q   +9 more
doaj  

Research Progress of RNA Molecules in Thyroid Cancer

open access: yesZhongliu Fangzhi Yanjiu, 2019
Thyroid cancer is the most common malignant tumor in the endocrine system, accounting for about 1% of all malignant tumors. At present, it has become a hot research topic to study the pathogenesis of thyroid cancer at the level of gene DNA.
LIN Lin, LIU Jianhua, WU Li'na
doaj   +1 more source

Multiple Isoforms of ANRIL in Melanoma Cells: Structural Complexity Suggests Variations in Processing [PDF]

open access: yes, 2017
The long non-coding RNA ANRIL, antisense to the CDKN2B locus, is transcribed from a gene that encompasses multiple disease-associated polymorphisms. Despite the identification of multiple isoforms of ANRIL, expression of certain transcripts has been ...
Askarian-Amiri, Marjan E.   +7 more
core   +1 more source

Engineering exosomal cargo loading via endogenous molecular pathways: Strategies to enhance therapeutic potential

open access: yesInterdisciplinary Medicine, EarlyView.
This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu   +6 more
wiley   +1 more source

Broad role for YBX1 in defining the small noncoding RNA composition of exosomes. [PDF]

open access: yes, 2017
RNA is secreted from cells enclosed within extracellular vesicles (EVs). Defining the RNA composition of EVs is challenging due to their coisolation with contaminants, lack of knowledge of the mechanisms of RNA sorting into EVs, and limitations of ...
Lambowitz, Alan M   +6 more
core   +1 more source

Recent Advances in Thalassemia Research: A Comprehensive Assessment From Diagnostic Technologies to Clinical Treatment

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Thalassemia, a common hereditary blood disorder causing impaired globin synthesis and related complications, has seen remarkable progress in recent years due to advancements in genomics and molecular biology. Researchers have identified various gene variants related to thalassemia and improved clinical diagnostic methods, including new genetic testing ...
Chaoqiong Zhou   +7 more
wiley   +1 more source

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