Results 111 to 120 of about 24,361 (224)

Oxidative and Antioxidant Systems in Ferroptosis of Cancer: Mechanisms, Regulations, and Therapeutic Targeting

open access: yesMedComm – Oncology, Volume 5, Issue 3, September 2026.
Ferroptosis is governed by the balance between reactive oxygen species (ROS)‐driven lipid peroxidation and a multi‐tiered antioxidant network. ROS sources include mitochondrial electron transport chain, voltage‐dependent anion channels, NADPH oxidases, and endoplasmic reticulum‐resident oxidoreductases, while antioxidant defenses span the primary GSH ...
Deepak K   +5 more
wiley   +1 more source

Genome–phenome association prediction using weighted deep matrix factorization with a multisource graph attention network

open access: yesQuantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Genome–phenome association (GPA) prediction can broaden the understanding of biological mechanisms underlying complex phenotypic traits (e.g., diseases and agronomic traits). Traditional deep matrix factorization (DMF)‐based GPA methods can integrate multiple data types and uncover nonlinear associations but often rely on low‐dimensional ...
Ran Duan   +4 more
wiley   +1 more source

Up-Regulation of circRNA hsa_circ_0003074 Expression is a Reliable Diagnostic and Prognostic Biomarker in Patients with Osteosarcoma

open access: yesCancer Management and Research, 2020
Saiyun Lei,1 Lei Xiang2 1Department of Joint Surgical, The Second Affiliated Hospital of University of South China, Hengyang 421001, People’s Republic of China; 2Department of Traumatic Orthopedics, Affiliated Nanhua Hospital, University of South ...
Lei S, Xiang L
doaj  

In Vitro Sperm–Epididymosomes Interaction Immediately Before Fertilization Changes Sperm Fertility Potential

open access: yesAndrology, Volume 14, Issue 6, Page 1757-1770, September 2026.
ABSTRACT Background Sperm acquire fertility ability during epididymal maturation mainly in the epididymal caput and corpus, and once matured, are stored in the epididymal cauda. During storage, interactions with cauda epididymosomes (epEVs) may influence sperm fertility potential; however, the role of such interactions on sperm fertility remains ...
Maíra Bianchi Rodrigues Alves   +7 more
wiley   +1 more source

The Biogenesis, Functions, and Roles of circRNAs in Bladder Cancer

open access: yesCancer Management and Research, 2020
Changjiu Li,1,* Xian Fu,2,* Huadong He,1 Chao Chen,2 Yuyong Wang,2 Lugeng He2 1Department of Urology, Affiliated Hangzhou First People’s Hospital, Nanjing Medical University, Hangzhou 310006, Zhejiang Province, People’s Republic of China ...
Li C, Fu X, He H, Chen C, Wang Y, He L
doaj  

Small Extracellular Vesicles‐Derived Circ6718 Unlocks Stromal Remodeling and Serves as a Biomarker in Gastric Cancer

open access: yesAdvanced Science, Volume 13, Issue 43, 3 August 2026.
sEVs‐circ6718 serves as a promising serum biomarker for gastric cancer early diagnosis and prognosis, promoting malignant transformation in gastric cancer cells and GC‑MSC differentiation into CAFs. sEVs‑circ6718 holds potential as a biomarker for the early diagnosis and prognostic assessment of gastric cancer.
Fan Zhang   +7 more
wiley   +1 more source

A Solution for Exosome‐Based Analysis: Surface‐Enhanced Raman Spectroscopy and Artificial Intelligence

open access: yesAdvanced Intelligent Discovery, Volume 2, Issue 4, August 2026.
Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz   +2 more
wiley   +1 more source

Exploring hsa_circ_0100833 as a Potential Biomarker in Oral Squamous Cell Carcinoma: Bioinformatics and Experimental Insights

open access: yesClinical and Experimental Dental Research, Volume 12, Issue 4, August 2026.
ABSTRACT Objectives Oral squamous cell carcinoma (OSCC) is an aggressive malignancy with few reliable early diagnostic markers. Bioinformatic screening identified hsa_circ_0100833 as a differentially expressed circRNA in OSCC. Its potential significance in OSCC was then examined experimentally.
Behnaz Raei   +4 more
wiley   +1 more source

Differential Expressions of circRNAs and Regulatory Mechanisms of ceRNA Network in Liver of Wilson’s Disease TX Mice

open access: yesJournal of Inflammation Research
Hong Chen,* Xie Wang,* Nian Peng, Yue Pu, Hao Ye, Yu Gui, Rui Zhang, Juan Zhang Department of Neurology, The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei, 230031, People’s Republic of China*These ...
Chen H   +7 more
doaj  

CircRNA-derived pseudogenes [PDF]

open access: yesCell Research, 2016
Dong, Rui   +5 more
openaire   +2 more sources

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