Results 111 to 120 of about 24,361 (224)
Ferroptosis is governed by the balance between reactive oxygen species (ROS)‐driven lipid peroxidation and a multi‐tiered antioxidant network. ROS sources include mitochondrial electron transport chain, voltage‐dependent anion channels, NADPH oxidases, and endoplasmic reticulum‐resident oxidoreductases, while antioxidant defenses span the primary GSH ...
Deepak K +5 more
wiley +1 more source
Abstract Genome–phenome association (GPA) prediction can broaden the understanding of biological mechanisms underlying complex phenotypic traits (e.g., diseases and agronomic traits). Traditional deep matrix factorization (DMF)‐based GPA methods can integrate multiple data types and uncover nonlinear associations but often rely on low‐dimensional ...
Ran Duan +4 more
wiley +1 more source
Saiyun Lei,1 Lei Xiang2 1Department of Joint Surgical, The Second Affiliated Hospital of University of South China, Hengyang 421001, People’s Republic of China; 2Department of Traumatic Orthopedics, Affiliated Nanhua Hospital, University of South ...
Lei S, Xiang L
doaj
ABSTRACT Background Sperm acquire fertility ability during epididymal maturation mainly in the epididymal caput and corpus, and once matured, are stored in the epididymal cauda. During storage, interactions with cauda epididymosomes (epEVs) may influence sperm fertility potential; however, the role of such interactions on sperm fertility remains ...
Maíra Bianchi Rodrigues Alves +7 more
wiley +1 more source
The Biogenesis, Functions, and Roles of circRNAs in Bladder Cancer
Changjiu Li,1,* Xian Fu,2,* Huadong He,1 Chao Chen,2 Yuyong Wang,2 Lugeng He2 1Department of Urology, Affiliated Hangzhou First People’s Hospital, Nanjing Medical University, Hangzhou 310006, Zhejiang Province, People’s Republic of China ...
Li C, Fu X, He H, Chen C, Wang Y, He L
doaj
sEVs‐circ6718 serves as a promising serum biomarker for gastric cancer early diagnosis and prognosis, promoting malignant transformation in gastric cancer cells and GC‑MSC differentiation into CAFs. sEVs‑circ6718 holds potential as a biomarker for the early diagnosis and prognostic assessment of gastric cancer.
Fan Zhang +7 more
wiley +1 more source
Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz +2 more
wiley +1 more source
ABSTRACT Objectives Oral squamous cell carcinoma (OSCC) is an aggressive malignancy with few reliable early diagnostic markers. Bioinformatic screening identified hsa_circ_0100833 as a differentially expressed circRNA in OSCC. Its potential significance in OSCC was then examined experimentally.
Behnaz Raei +4 more
wiley +1 more source
Hong Chen,* Xie Wang,* Nian Peng, Yue Pu, Hao Ye, Yu Gui, Rui Zhang, Juan Zhang Department of Neurology, The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei, 230031, People’s Republic of China*These ...
Chen H +7 more
doaj

