Results 91 to 100 of about 28,713 (267)

Hsa_circ_0017728 as an oncogene in gastric cancer by sponging miR-149 and modulating the IL-6/STAT3 pathway

open access: yesArchives of Medical Science, 2019
Introduction Circular RNAs (circRNAs) have been identified as competing endogenous RNAs (ceRNAs) to mediate gene expression participating in the progression of multiple cancers, including gastric carcinoma (GC).
Chun Yang, Shaoping Deng
doaj   +1 more source

Review of the Molecular and Developmental Basis of Myhre Syndrome, Bench Research

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome (MS) is a connective‐tissue disorder within the acromelic dysplasia spectrum. It is characterized by congenital craniofacial, skeletal, cutaneous anomalies, respiratory, cardiovascular along with intellectual disability, deafness, and progressive fibrosis.
Camille Viaut, Valerie Cormier‐Daire
wiley   +1 more source

Table3_High-Throughput Sequencing to Investigate lncRNA-circRNA-miRNA-mRNA Networks Underlying the Effects of Beta-Amyloid Peptide and Senescence on Astrocytes.XLSX

open access: yes, 2022
Astrocytes are widely distributed in the central nervous system and play an essential role in the function of neuronal cells. Associations between astrocytes and Alzheimer’s disease (AD) have been noted, and recent work has implicated circular RNA ...
Jiuyang Ding (9509180)   +7 more
core   +1 more source

Circular RNAs: implications of signaling pathways and bioinformatics in human cancer

open access: yesCancer Biology & Medicine, 2023
Circular RNAs (circRNAs) form a class of endogenous single-stranded RNA transcripts that are widely expressed in eukaryotic cells. These RNAs mediate post-transcriptional control of gene expression and have multiple functions in biological processes ...
Fan Hu   +4 more
doaj   +1 more source

One‐step generation of heritable mitochondrial DNA multiplex‐engineered rats using DddA‐derived cytosine base editor

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang   +14 more
wiley   +1 more source

Table4_High-Throughput Sequencing to Investigate lncRNA-circRNA-miRNA-mRNA Networks Underlying the Effects of Beta-Amyloid Peptide and Senescence on Astrocytes.XLSX

open access: yes, 2022
Astrocytes are widely distributed in the central nervous system and play an essential role in the function of neuronal cells. Associations between astrocytes and Alzheimer’s disease (AD) have been noted, and recent work has implicated circular RNA ...
Jiuyang Ding (9509180)   +7 more
core   +1 more source

Role of non-coding RNAs in skin photoaging

open access: yesPifu-xingbing zhenliaoxue zazhi
Skin photoaging, a phenomenon of premature skin aging due to prolonged exposure to ultraviolet (UV) radiation, manifests as wrinkles, loss of skin elasticity, pigmentation disorders, and age spots.
HE Zezhi   +5 more
doaj   +1 more source

Orchestrating the metastatic symphony: the role of extracellular vesicles in the epithelial–mesenchymal transition and pulmonary niche formation of breast cancer

open access: yesBiological Reviews, EarlyView.
ABSTRACT The complexity of breast cancer (BC) lung metastasis lies in the capacity of tumour cells to interact efficiently with distant organs to promote colonisation, a process that involves the sophisticated coordination of inherent cellular plasticity and the remodelling of the distant microenvironment.
Jian Lu   +12 more
wiley   +1 more source

CircRNA-miRNA-hubgene network.

open access: yes, 2019
The network consists of 10 circRNAs, 5 miRNAs, and 10 hub_genes. Vs indicate circRNAs, diamonds indicate miRNA, and round rectangles indicate mRNA.
Wei-dong Jiang (7114763)   +1 more
core   +1 more source

Experimental validation of circRNA candidates.

open access: yes, 2023
(A) Schematics of the biogenesis of circRNA candidates and gene structure of their host genes. Black line represents intron, whereas rectangle indicates exon.
Yulan Chen (1788139)   +6 more
core   +1 more source

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