Results 81 to 90 of about 34,260 (269)
Objective To explore the effects of the interaction between circular RNA hsa_circ_0000231 and HnRNPK on the proliferation, migration and apoptosis in breast cancer. Methods Microarray analysis was used to investigate the expression profile of circRNAs in
HU Mengting, CHEN Junxia
doaj +1 more source
Performance assessment of total RNA sequencing of human biofluids and extracellular vesicles [PDF]
RNA profiling has emerged as a powerful tool to investigate the biomarker potential of human biofluids. However, despite enormous interest in extracellular nucleic acids, RNA sequencing methods to quantify the total RNA content outside cells are rare ...
Anckaert, Jasper +13 more
core +1 more source
Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz +2 more
wiley +1 more source
Association of microRNA-7 and its binding partner CDR1-AS with the prognosis and prediction of 1st-line tamoxifen therapy in breast cancer [PDF]
The large number of non-coding RNAs (ncRNAs) and their breadth of functionalities has fuelled many studies on their roles in cancer. We previously linked four microRNAs to breast cancer prognosis.
Foekens, J.A. (John) +6 more
core +3 more sources
We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang +14 more
wiley +1 more source
CircRNAs and Fusion-circRNAs in cancer: New players in an old game
Circular RNAs (circRNAs) are generated from 'back-splicing' events. Their circular structure makes them stable in cells and body fluids. These entities are involved in several human diseases including cancer, as they affect the expression of genes promoting proliferation, invasion, apoptosis, and angiogenesis.
Grazia Visci +5 more
openaire +3 more sources
Lianbo Hu,1 Bingrong Zheng,2 Yang Yang,2 Chunmei Chen,2 Meiwei Hu2 1Physical Examination Center, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People’s Republic of China; 2Department of ...
Hu L, Zheng B, Yang Y, Chen C, Hu M
doaj
The Recent Research Progress of CircRNA in Bladder Cancer
Bladder cancer is a major public health problem in the world, and is one of the most common malignant tumors in the genito-urinary system. Due to its high incidence and mortality, it remains a serious threat to human health.
Shuo Liu, Xin-liang Xu
doaj +1 more source
An observation of circular RNAs in bacterial RNA-seq data [PDF]
Circular RNAs (circRNAs) are a class of RNA with an important role in micro RNA (miRNA) regulation recently discovered in Human and various other eukaryotes as well as in archaea.
Aurell, Erik +3 more
core +1 more source
FROM EPIGENETICS TO ANTI-DOPING APPLICATION: A NEW TOOL OF DETECTION [PDF]
Eukaryotic genomes transcribe up to 90% of the genomic DNA but only 1\u20132% of these transcripts encode for proteins, whereas the vast majority are transcribed as non-coding RNAs (ncRNAs). They are divided into short ncRNA, particularly microRNA (miRNA)
Cieszczyk, P. +5 more
core +1 more source

