Results 61 to 70 of about 30,287 (286)
Evaluation of coding capacity of circRNA-407.
(A) Left panel: Full mature sequence of circRNA-407. The sequences of the putative ORF were shown in red and the putative untranslated region was shown in green. Right panel: Schematic of putative ORF in circRNA-407.
Yulan Chen (1788139) +6 more
core +1 more source
Roles of circRNAs in the tumour microenvironment [PDF]
Abstract The tumour microenvironment (TME) constitutes the area surrounding the tumour during its development and has been demonstrated to play roles in cancer-related diseases through crosstalk with tumour cells. Circular RNAs (circRNAs) are a subpopulation of endogenous noncoding RNAs (ncRNAs) that are ubiquitously expressed in ...
Qiuge Zhang +7 more
openaire +3 more sources
The lariat-derived circRNA from ATXN2L: an outstanding circRNA in pigs
International audienceIn contrast to exon-derived circular RNAs (exonic circRNAs), which are widely studied, much less in known on intron-derived circRNAs: when intron lariats escape degradation due to debranching failure they can become circRNA ...
Faraut, Thomas +4 more
core +2 more sources
Cheng Xue,1 Yi Cheng,1 Jinyou Wu,1 Kongliang Ke,2 Chundi Miao,2 Enfu Chen,1 Luqing Zhang2 1Department of Endocrinology, Wenling First People’s Hospital, Wenling 317500, People’s Republic of China; 2Department of Anorectal Surgery, Ningbo ...
Xue C +6 more
doaj
Objective To investigate the expression of hsa_circ_0018574 in colorectal cancer tissues and human colon cancer HT29 cell line, as well as its effect on the proliferation and apoptosis of colorectal cancer cells.
MA Rui +5 more
doaj +1 more source
Plasma circRNAs as Biomarkers in Cancer
The incidence and mortality of cancer are increasing each year. At present, the sensitivity and specificity of the blood biomarkers that were used in clinical practice are low, which make the detection rate of cancer decrease. With advances in bioinformatics and technology, some non-coding RNA as biomarkers can be easily detected through some ...
Qian Zhou +5 more
openaire +4 more sources
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Construction of a circRNA-Mediated ceRNA Network Reveals Novel Biomarkers for Aortic Dissection
De-Bin Liu,1,* You-Fu He,2– 4,* Gui-Jian Chen,1 Hua Huang,1 Xu-Ling Xie,1 Wan-Jun Lin,1 Zhi-Jian Peng1 1Department of Cardiology, The Second People’s Hospital of Shantou, Shantou, Guangdong Province, People’s Republic of China; 2Department of ...
Liu DB +6 more
doaj
The aim of this study is to explore the prognostic value of vascular invasion (VI) in hepatocellular carcinoma (HCC) by searching for competing endogenous RNAs (ceRNA) network and constructing a new prognostic model for HCC.
Liu Yun +6 more
doaj +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source

