Results 41 to 50 of about 28,713 (267)
CircRNA-407 sponged miR-9a-5p to regulate ovarian development.
, 2023 (A) The putative miR-9a-5p binding site in circRNA-407 was predicted by RNAhybrid. (B) Schematic diagram of dual-luciferase reporter gene structure based on pmir-GLO plasmid. The putative binding sites (WT-circRNA-407) and the mutant version (MUT-circRNA-
Yulan Chen (1788139) +6 more
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The Promising Role of MicroRNAs, Long Non-Coding RNAs and Circular RNAs in Urological Malignancies [PDF]
Translational Research in Urology, 2022 Nowadays, non-communicable diseases are the leading cause of death worldwide. Cancer management has been a significant challenge for public health in the last decade.
Helia Azodian Ghajar +1 more
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CircRNA expression profile and circRNA-miRNA-mRNA crosstalk in allergic rhinitis [PDF]
World Allergy Organization Journal, 2020 Circular RNAs (circRNAs) are involved in inflammation; however, their role in allergic rhinitis (AR) remains unclear. In this study, we analyzed circRNA expression and identified a circRNA-miRNA-mRNA network through which circRNAs regulate AR pathogenesis.We analyzed circRNA, miRNA, and mRNA expression profiles in the nasal mucosa by high-throughput ...
Chang-Yu Qiu +7 more
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, 2022 IntroductionSpinal cord injury (SCI) often causes continuous neurological damage to clinical patients. Circular RNAs (circRNAs) are related to a lot of diseases, including SCI. We previously found five candidate circRNAs which were likely to regulate the
Yi Liu (36759) +11 more
core +1 more source
Mechanisms of non-coding RNA-modulated alternative splicing in cancer
RNA Biology, 2022 Alternative splicing (AS) is a common and pivotal process for eukaryotic gene expression regulation, which enables a precursor RNA to produce multiple transcript variants with diverse cellular functions.
Xiaolin Wang +6 more
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陆军军医大学学报, 2022 Objective To explore the effects of the interaction between circular RNA hsa_circ_0000231 and HnRNPK on the proliferation, migration and apoptosis in breast cancer. Methods Microarray analysis was used to investigate the expression profile of circRNAs in
HU Mengting, CHEN Junxia
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Molecular Medicine Reports, 2022 Circular RNA (circRNA) molecules are noncoding RNAs with unique circular covalently closed structures that contribute to gene expression regulation, protein translation and act as microRNA sponges. circRNAs also have important roles in human disease, particularly tumorigenesis and antitumor processes.
Zhang, Chunlei +8 more
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Analysis of circRNAs and circRNA-associated competing endogenous RNA networks in β-thalassemia [PDF]
Scientific Reports, 2022 AbstractThe involvement of circRNAs in β-thalassemia and their actions on fetal hemoglobin (HbF) is unclear. Here, the circRNAs in β-thalassemia carriers with high HbF levels were comprehensively analyzed and compared with those of healthy individuals.
Fang Yang +9 more
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Regulation of circRNA biogenesis [PDF]
RNA Biology, 2015 Unlike linear RNAs terminated with 5' caps and 3' tails, circular RNAs are characterized by covalently closed loop structures with neither 5' to 3' polarity nor polyadenylated tail. This intrinsic characteristic has led to the general under-estimation of the existence of circular RNAs in previous polyadenylated transcriptome analyses.
Ling-Ling, Chen, Li, Yang
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Overexpression of circRNA and RfxCas13d-mediated circRNA knockdown.
, 2023 (A) Schematic of circRNA-407 overexpression plasmid. Expression of circRNA-407 was driven by AePUb promoter and circularization of LOC109412837 exon 5 to exon 8 was facilitated by Drosophila DNAREP1-DM flanking intron.
Yulan Chen (1788139) +6 more
core +1 more source