Results 41 to 50 of about 24,361 (224)
CircRNAs: Insights into Gastric Cancer [PDF]
Gastrointestinal Tumors, 2021 <b><i>Background:</i></b> Gastric cancer (GC) is recorded as the fifth most common cancer globally. The classic resemblance of early symptoms of chronic gastritis including nausea, dysphagia, and dyspepsia with GC is the current challenge limiting the early diagnosis of GC. The current diagnostic procedures of GC are limited due
Sanjana, Rajgopal +2 more
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Circular RNAs: A Promising Biomarker for Endometrial Cancer
Cancer Management and Research, 2021 Jialu Guo,1,2 Jinyi Tong,1,2 Jianfeng Zheng2,3 1Department of the Fourth Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, 310008, People’s Republic of China; 2Department of Obstetrics and Gynecology ...
Guo J, Tong J, Zheng J
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CircPrimer 2.0: a software for annotating circRNAs and predicting translation potential of circRNAs
BMC Bioinformatics, 2022 Abstract Background Some circular RNAs (circRNAs) can be translated into functional peptides by small open reading frames (ORFs) in a cap-independent manner. Internal ribosomal entry site (IRES) and N6-methyladenosine (m6A) were reported to drive translation of circRNAs.
Shanliang Zhong, Jifeng Feng
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CircRNAs and Fusion-circRNAs in cancer: New players in an old game
Cellular Signalling, 2020 Circular RNAs (circRNAs) are generated from 'back-splicing' events. Their circular structure makes them stable in cells and body fluids. These entities are involved in several human diseases including cancer, as they affect the expression of genes promoting proliferation, invasion, apoptosis, and angiogenesis.
Grazia Visci +5 more
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The Potential Role of hsa_circ_0004214 as a Biomarker for Breast Cancer Prognosis [PDF]
Journal of EpigeneticsBreast cancer is the most important cause of cancer-related death among women. Finding cancer management biomarkers may improve cancer management strategies, patient outcomes, and quality of life.
Marzieh Beikzadeh, Mahdieh Salimi
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Roles of circRNAs in the tumour microenvironment [PDF]
Molecular Cancer, 2020 Abstract The tumour microenvironment (TME) constitutes the area surrounding the tumour during its development and has been demonstrated to play roles in cancer-related diseases through crosstalk with tumour cells. Circular RNAs (circRNAs) are a subpopulation of endogenous noncoding RNAs (ncRNAs) that are ubiquitously expressed in ...
Qiuge Zhang +7 more
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Cancer Management and Research, 2020 Cheng Xue,1 Yi Cheng,1 Jinyou Wu,1 Kongliang Ke,2 Chundi Miao,2 Enfu Chen,1 Luqing Zhang2 1Department of Endocrinology, Wenling First People’s Hospital, Wenling 317500, People’s Republic of China; 2Department of Anorectal Surgery, Ningbo ...
Xue C +6 more
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Zhongliu Fangzhi Yanjiu, 2022 Objective To investigate the expression of hsa_circ_0018574 in colorectal cancer tissues and human colon cancer HT29 cell line, as well as its effect on the proliferation and apoptosis of colorectal cancer cells.
MA Rui +5 more
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Advanced Science, EarlyView.An RVG‑engineered exosomal saRNA delivery system (RVG‑EVs‑saPtpro) effectively targets and activates hippocampal PTPRO, functioning as a “molecular brake” to alleviate cancer therapy‑related cognitive impairment (CTRCI) by enhancing neuronal survival, neurogenesis, and synaptic plasticity.
Zhimeng Yao +18 more
wiley +1 more source
Construction of a circRNA-Mediated ceRNA Network Reveals Novel Biomarkers for Aortic Dissection
International Journal of General Medicine, 2022 De-Bin Liu,1,* You-Fu He,2– 4,* Gui-Jian Chen,1 Hua Huang,1 Xu-Ling Xie,1 Wan-Jun Lin,1 Zhi-Jian Peng1 1Department of Cardiology, The Second People’s Hospital of Shantou, Shantou, Guangdong Province, People’s Republic of China; 2Department of ...
Liu DB +6 more
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