Results 31 to 40 of about 24,361 (224)

Mechanisms of non-coding RNA-modulated alternative splicing in cancer

open access: yesRNA Biology, 2022
Alternative splicing (AS) is a common and pivotal process for eukaryotic gene expression regulation, which enables a precursor RNA to produce multiple transcript variants with diverse cellular functions.
Xiaolin Wang   +6 more
doaj   +1 more source

Effect of circular RNA hsa_circ_0000231 interacting with HnRNPK on proliferation, migration, and apoptosis in breast cancer

open access: yes陆军军医大学学报, 2022
Objective To explore the effects of the interaction between circular RNA hsa_circ_0000231 and HnRNPK on the proliferation, migration and apoptosis in breast cancer. Methods Microarray analysis was used to investigate the expression profile of circRNAs in
HU Mengting, CHEN Junxia
doaj   +1 more source

Regulation of circRNA biogenesis [PDF]

open access: yesRNA Biology, 2015
Unlike linear RNAs terminated with 5' caps and 3' tails, circular RNAs are characterized by covalently closed loop structures with neither 5' to 3' polarity nor polyadenylated tail. This intrinsic characteristic has led to the general under-estimation of the existence of circular RNAs in previous polyadenylated transcriptome analyses.
Ling-Ling, Chen, Li, Yang
openaire   +2 more sources

The Recent Research Progress of CircRNA in Bladder Cancer

open access: yesAnnals of Urologic Oncology, 2023
Bladder cancer is a major public health problem in the world, and is one of the most common malignant tumors in the genito-urinary system. Due to its high incidence and mortality, it remains a serious threat to human health.
Shuo Liu, Xin-liang Xu
doaj   +1 more source

Research Progress on Non-coding RNAs in Cholesteatoma of the Middle Ear [PDF]

open access: yesClinical and Experimental Otorhinolaryngology, 2023
Cholesteatoma of the middle ear is a common disease in otolaryngology that is receiving increasing attention. It is estimated that over five million people around the world have suffered from middle ear cholesteatoma.
Dongliang Liu   +3 more
doaj   +1 more source

circRNA18_46222157_46248185 inhibits melanogenesis by targeting miR-211/ pathway in goat melanocytes [PDF]

open access: yesAnimal Bioscience
Objective This study investigated the effects of circRNA18_46222157_46248185 (named circRNA18) on goat melanogenesis, which differs significantly in goat skins isolated from white and brown coat-colored skins.
Kai Yuan Ji   +5 more
doaj   +1 more source

CircPrimer: a software for annotating circRNAs and determining the specificity of circRNA primers [PDF]

open access: yesBMC Bioinformatics, 2018
Since circular RNAs (circRNAs) post-transcriptionally regulate gene expression, they have attracted increasing attention. However, there is no existing tool to annotate and extract spliced sequences for circRNAs and no tool to determine the specificity of circRNA primers.In this study, we present circPrimer, which allows users to search, annotate, and ...
Shanliang Zhong   +4 more
openaire   +3 more sources

Crosstalk between m6A mRNAs and m6A circRNAs and the time-specific biogenesis of m6A circRNAs after OGD/R in primary neurons

open access: yesEpigenetics, 2023
Cerebral ischaemiareperfusion injury is an important pathological process in nervous system diseases during which neurons undergo oxygenglucose deprivation and reoxygenation (OGD/R) injury.
Chi Zhang   +12 more
doaj   +1 more source

Circular RNAs

open access: yesEXCLI Journal : Experimental and Clinical Sciences, 2023
Circular RNAs (CircRNAs) are a class of regulatory RNA transcripts, which are ubiquitously expressed in eukaryotes. CircRNA dysregulation has been shown to disrupt the interaction of the Wnt/β-catenin pathway, which regulates several biological processes
Mina Alimohammadi   +7 more
doaj   +1 more source

YTHDC1-Modified m6A Methylation of Hsa_circ_0102678 Promotes Keratinocyte Inflammation Induced by Cutibacterium acnes Biofilm through Regulating miR-146a/TRAF6 and IRAK1 Axis

open access: yesJournal of Innate Immunity, 2023
Introduction: CircRNAs are closely related to many human diseases; however, their role in acne remains unclear. This study aimed to determine the role of hsa_circ_0102678 in regulating inflammation of acne.
Meng Zhou   +11 more
doaj   +1 more source

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