Results 11 to 20 of about 34,489 (213)
Cancer Management and Research, 2021 Weihong Lin,* Zuopeng Wang,* Jing Wang, Hanlei Yan, Qilei Han, Wei Yao, Kai Li Department of Pediatric Surgery, Children’s Hospital of Fudan University, National Children’s Medical Center, Shanghai, People’s Republic of China*These ...
Kai Li, Wei Yao, Zuopeng Wang
exaly +2 more sources
PIAS3 CircRNA-Loaded Lipid Nanoparticles Restore ALOX15 SUMOylation to Suppress Cementoblast Ferroptosis and Attenuate Orthodontically Induced Root Resorption. [PDF]
Adv Sci (Weinh)Orthodontic compression suppresses PIAS3 expression in cementoblasts, impairing ALOX15 SUMOylation and ubiquitin‐mediated degradation, which leads to ALOX15 accumulation, lipid peroxidation, ferroptosis, and osteoclastogenesis. Local delivery of PIAS3 circRNA‐loaded lipid nanoparticles restores the PIAS3–ALOX15 regulatory pathway, alleviates ...
Hou Y +11 more
europepmc +2 more sources
Circular RNAs in Cervical Cancer: What are the Prospects?
Креативная хирургия и онкология, 2023 C ervical cancer remains a pressing global health problem, creating a significant health burden for women worldwide. High incidence and mortality rates necessitate further research to unravel its underlying molecular mechanisms and identify new ...
S. A. Begliarzade, R. I. Tamrazov
doaj +1 more source
Unveiling Circular RNA-Mediated Regulatory Mechanisms in Necroptosis in Premature Ovarian Failure
Frontiers in Bioscience-Landmark, 2023 Background: Necroptosis is a programmed necrotic cell death, in which dying cells rupture and release intracellular components that trigger a proinflammatory response.
Xin Jin +6 more
doaj +1 more source
Identification of a lncRNA/circRNA-miRNA-mRNA ceRNA Network in Alzheimer's Disease
Journal of Integrative Neuroscience, 2023 Background: Alzheimer’s disease (AD) occurs in the elderly and pre-elderly, characterized by decline of memory, cognitive dysfunction, impairment of learning capacity, and motor dysfunction.
Lining Su +3 more
doaj +1 more source
陆军军医大学学报, 2023 Objective To investigate the effects of intraperitoneal injection of islet amyloid polypeptide (IAPP) on the expression profiles of circular RNAs (circRNAs) and messenger RNAs (mRNAs) in the brain tissue of Alzheimer's disease (AD) mice and wild-type ...
HOU Mingliang +3 more
doaj +1 more source
Circular Ribonucleic Acid Expression in Patient with Acne [PDF]
Egyptian Journal of Medical Research, 2022 Background: Acne is a common chronic skin disease with a multifactorial aetiology and pathogenesis. Recently, circular RNAs (circRNAs) have been identified as a key factor in regulating gene expression through circRNA–miRNA–mRNA networks in many ...
Abd-Elaziz El-Taweel +3 more
doaj +1 more source
口腔疾病防治, 2020 Objective To explore the effect of circ_0001273 on the proliferation, migration and invasion of oral squamous cell carcinoma（OSCC） cells and to provide a relevant research basis for the use of targeted therapy in OSCC.
ZENG Fantao, YU Dongsheng
doaj +1 more source
Open Life Sciences, 2022 Circular RNAs (circRNAs) have previously been confirmed to function as vital regulators in multiple human cancers, including hepatocellular carcinoma (HCC). This study aimed to clarify the role and underlying molecular mechanisms of circ-CFH in HCC. circ-
Chen Zengyin +4 more
doaj +1 more source