Results 11 to 20 of about 30,287 (286)
CircRNA Role and circRNA-Dependent Network (ceRNET) in Asthenozoospermia [PDF]
Frontiers in Endocrinology, 2020 The role of circRNA in reproduction is under investigation. CircRNAs are expressed in human testis, spermatozoa (SPZ), and seminal plasma. Their involvement in embryo development has also been suggested.
Francesco Manfrevola +8 more
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Cancer Management and Research, 2021 Weihong Lin,* Zuopeng Wang,* Jing Wang, Hanlei Yan, Qilei Han, Wei Yao, Kai Li Department of Pediatric Surgery, Children’s Hospital of Fudan University, National Children’s Medical Center, Shanghai, People’s Republic of China*These ...
Lin W +6 more
doaj +4 more sources
From circRNAs to fusion circRNAs in hematological malignancies [PDF]
JCI Insight, 2021 Circular RNAs (circRNAs) represent a type of endogenous noncoding RNA generated by back-splicing events. Unlike the majority of RNAs, circRNAs are covalently closed, without a 5 ′ end or a 3 ′ poly(A) tail.
Babin, Loelia +5 more
openaire +4 more sources
CircRNA May Not Be “Circular” [PDF]
Frontiers in Genetics, 2021 Circular RNA (circRNA) is a novel regulatory non-coding RNA and participates in diverse physiological and pathological processes. However, the structures and molecular mechanisms of circRNAs remain unclear. In this study, taking advantage of openly databases and bioinformatics analysis, we observed lots of internal complementary base-pairing sequences (
Handong Sun +14 more
openaire +3 more sources
Molecular Cell, 2017 Circular RNAs (circRNAs) are abundant and evolutionarily conserved RNAs of largely unknown function. Here, we show that a subset of circRNAs is translated in vivo. By performing ribosome footprinting from fly heads, we demonstrate that a group of circRNAs is associated with translating ribosomes.
Pamudurti, Nagarjuna Reddy +16 more
openaire +3 more sources
RNA Biology, 2016 Circular RNAs (circRNAs) are highly abundant and evolutionarily conserved non-coding RNAs produced by circularization of specific exons. Since their re-discovery as potential regulators of gene expression, thousands of circRNAs were detected in different tissues and cell types across most organisms.
Mor, Hanan +2 more
openaire +2 more sources
Current Opinion in Genetics & Development, 2018 Exonic circular RNAs (circRNAs) are mostly generated from exons of protein-coding genes and, in many cases, are more abundant that the linear product from their hosting gene. Certain circRNAs are very abundant in the brain and in non-dividing cells; and many also show physiological-specific and tissue-specific expression.
Patop, Ines Lucia, Kadener, Sebastian
openaire +2 more sources
The invasion of circRNAs [PDF]
RNA Biology, 2017 Single-stranded covalently closed circular RNA (circRNA) molecules come in many disguises, with different biogenesis mechanisms and functions.
Thomas B, Hansen, Jørgen, Kjems
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Characterizing viral circRNAs and their application in identifying circRNAs in viruses
Briefings in Bioinformatics, 2021 Abstract Circular RNAs (circRNAs) are non-coding RNAs with a special circular structure produced formed by the reverse splicing mechanism, which play an important role in a variety of biological activities. Viruses can encode circRNA, and viral circRNAs have been found in multiple single-stranded and double-stranded viruses. However, the
Mengting Niu +3 more
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Prediction of circRNA-miRNA Associations Based on Network Embedding [PDF]
, 2021 circRNA is a novel class of noncoding RNA with closed-loop structure. Increasing biological experiments have shown that circRNAs play an important role in many diseases by acting as a miRNA sponge to indirectly regulate the expression of miRNA target ...
Chen, Jianwei +23 more
core +1 more source