Results 21 to 30 of about 30,287 (286)
Increased expression of the circular RNA generated by the sulfateless gene (circSfl), and of the protein it encodes, can extend the lifespan of flies.
openaire +2 more sources
LncRNAs and CircRNAs in cancer
AbstractIt is well known that noncoding RNAs (ncRNAs) cannot encode proteins, but they can play important regulatory roles in tumors by combining with proteins, RNAs, and DNAs. As more and more studies reveal the important roles and underlying mechanisms of long noncoding RNAs (lncRNAs) and circular RNAs (circRNAs) in cancer, their huge application ...
Xin Yin +5 more
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circRNA-sponging: a pipeline for extensive analysis of circRNA expression and their role in miRNA sponging [PDF]
ABSTRACT Motivation Circular RNAs (circRNAs) are long non-coding RNAs (lncRNAs) often associated with diseases and considered potential biomarkers for diagnosis and treatment. Among other functions, circRNAs have been shown to act as microRNA (miRNA) sponges, preventing the role of miRNAs that ...
Markus Hoffmann +10 more
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CircRNA-407 could act as miRNA sponge.
(A) Venn diagram showing the putative miRNAs interacting with circRNA-407 predicted by miRanda, RNAhybrid and TargetScan. (B) and (C) Dynamic expression levels of miR-9a-5p (B) or miR-989-3p (C) in fat body of female mosquitoes (n = 15 females per ...
Yulan Chen (1788139) +6 more
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PF-circRNA-Supplementary Tables.pdf
PF-circRNA-Supplementary Table 1 and ...
Jinqing Li (12509803)
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CircRNA-407 sponged miR-9a-5p to regulate ovarian development.
(A) The putative miR-9a-5p binding site in circRNA-407 was predicted by RNAhybrid. (B) Schematic diagram of dual-luciferase reporter gene structure based on pmir-GLO plasmid. The putative binding sites (WT-circRNA-407) and the mutant version (MUT-circRNA-
Yulan Chen (1788139) +6 more
core +1 more source
CircRNAs in Tumor Radioresistance
Circular RNAs (circRNAs) are endogenous, non-coding RNAs, which are derived from host genes that are present in several species and can be involved in the progression of various diseases. circRNAs’ leading role is to act as RNA sponges. In recent years, the other roles of circRNAs have been discovered, such as regulating transcription and translation ...
Yining Gao +7 more
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RNA sequencing reveals a regulatory network of circRNA-miRNA-mRNA ceRNA in Wilms tumor
Objective To identify the potential circRNA-miRNA-mRNA regulatory networks in Wilms tumor (WT) based on high-throughput RNA sequencing technology and bioinformatics analysis.
XIANG Bin +4 more
doaj +1 more source
circRNA-miRNA-mRNA regulation network.
ObjectiveSince circRNA can be utilized as a potential diagnostic marker for cancer, to explore the regulatory mechanism of colorectal cancer (CRC) using bioinformatics, the public database of circRNA was mined.MethodsCRC differentially expressed miRNAs ...
Lei Xu (78676) +3 more
core +1 more source

