Results 21 to 30 of about 24,361 (224)
LncRNAs and CircRNAs in cancer
MedComm, 2022 AbstractIt is well known that noncoding RNAs (ncRNAs) cannot encode proteins, but they can play important regulatory roles in tumors by combining with proteins, RNAs, and DNAs. As more and more studies reveal the important roles and underlying mechanisms of long noncoding RNAs (lncRNAs) and circular RNAs (circRNAs) in cancer, their huge application ...
Xin Yin +5 more
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Nature Reviews Molecular Cell Biology, 2020 Increased expression of the circular RNA generated by the sulfateless gene (circSfl), and of the protein it encodes, can extend the lifespan of flies.
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circRNA-sponging: a pipeline for extensive analysis of circRNA expression and their role in miRNA sponging [PDF]
Bioinformatics Advances, 2023 ABSTRACT Motivation Circular RNAs (circRNAs) are long non-coding RNAs (lncRNAs) often associated with diseases and considered potential biomarkers for diagnosis and treatment. Among other functions, circRNAs have been shown to act as microRNA (miRNA) sponges, preventing the role of miRNAs that ...
Markus Hoffmann +10 more
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The role of circRNAs in cancers [PDF]
Bioscience Reports, 2017 Circular RNAs (circRNAs) are recently regarded as a naturally forming family of widespread and diverse endogenous noncoding RNAs (ncRNAs) that may regulate gene expression in mammals. At present, above 30000 circRNAs have already been found, with their unique structures to maintain stability more easily than linear RNAs.
Zhu, Ling-Ping +11 more
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CircRNAs in Tumor Radioresistance
Biomolecules, 2022 Circular RNAs (circRNAs) are endogenous, non-coding RNAs, which are derived from host genes that are present in several species and can be involved in the progression of various diseases. circRNAs’ leading role is to act as RNA sponges. In recent years, the other roles of circRNAs have been discovered, such as regulating transcription and translation ...
Yining Gao +7 more
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RNA sequencing reveals a regulatory network of circRNA-miRNA-mRNA ceRNA in Wilms tumor
陆军军医大学学报, 2022 Objective To identify the potential circRNA-miRNA-mRNA regulatory networks in Wilms tumor (WT) based on high-throughput RNA sequencing technology and bioinformatics analysis.
XIANG Bin +4 more
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Analysis of circRNAs and circRNA-associated competing endogenous RNA networks in β-thalassemia [PDF]
Scientific Reports, 2022 AbstractThe involvement of circRNAs in β-thalassemia and their actions on fetal hemoglobin (HbF) is unclear. Here, the circRNAs in β-thalassemia carriers with high HbF levels were comprehensively analyzed and compared with those of healthy individuals.
Fang Yang +9 more
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The Promising Role of MicroRNAs, Long Non-Coding RNAs and Circular RNAs in Urological Malignancies [PDF]
Translational Research in Urology, 2022 Nowadays, non-communicable diseases are the leading cause of death worldwide. Cancer management has been a significant challenge for public health in the last decade.
Helia Azodian Ghajar +1 more
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Molecular Medicine Reports, 2022 Circular RNA (circRNA) molecules are noncoding RNAs with unique circular covalently closed structures that contribute to gene expression regulation, protein translation and act as microRNA sponges. circRNAs also have important roles in human disease, particularly tumorigenesis and antitumor processes.
Zhang, Chunlei +8 more
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CircRNA expression profile and circRNA-miRNA-mRNA crosstalk in allergic rhinitis [PDF]
World Allergy Organization Journal, 2020 Circular RNAs (circRNAs) are involved in inflammation; however, their role in allergic rhinitis (AR) remains unclear. In this study, we analyzed circRNA expression and identified a circRNA-miRNA-mRNA network through which circRNAs regulate AR pathogenesis.We analyzed circRNA, miRNA, and mRNA expression profiles in the nasal mucosa by high-throughput ...
Chang-Yu Qiu +7 more
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