Results 21 to 30 of about 28,713 (267)
Current Opinion in Genetics & Development, 2018 Exonic circular RNAs (circRNAs) are mostly generated from exons of protein-coding genes and, in many cases, are more abundant that the linear product from their hosting gene. Certain circRNAs are very abundant in the brain and in non-dividing cells; and many also show physiological-specific and tissue-specific expression.
Patop, Ines Lucia, Kadener, Sebastian
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陆军军医大学学报, 2023 Objective To investigate the effects of intraperitoneal injection of islet amyloid polypeptide (IAPP) on the expression profiles of circular RNAs (circRNAs) and messenger RNAs (mRNAs) in the brain tissue of Alzheimer's disease (AD) mice and wild-type ...
HOU Mingliang +3 more
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The invasion of circRNAs [PDF]
RNA Biology, 2017 Single-stranded covalently closed circular RNA (circRNA) molecules come in many disguises, with different biogenesis mechanisms and functions.
Thomas B, Hansen, Jørgen, Kjems
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Circular Ribonucleic Acid Expression in Patient with Acne [PDF]
Egyptian Journal of Medical Research, 2022 Background: Acne is a common chronic skin disease with a multifactorial aetiology and pathogenesis. Recently, circular RNAs (circRNAs) have been identified as a key factor in regulating gene expression through circRNA–miRNA–mRNA networks in many ...
Abd-Elaziz El-Taweel +3 more
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Characterizing viral circRNAs and their application in identifying circRNAs in viruses
Briefings in Bioinformatics, 2021 Abstract Circular RNAs (circRNAs) are non-coding RNAs with a special circular structure produced formed by the reverse splicing mechanism, which play an important role in a variety of biological activities. Viruses can encode circRNA, and viral circRNAs have been found in multiple single-stranded and double-stranded viruses. However, the
Mengting Niu +3 more
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Prediction of circRNA-miRNA Associations Based on Network Embedding [PDF]
, 2021 circRNA is a novel class of noncoding RNA with closed-loop structure. Increasing biological experiments have shown that circRNAs play an important role in many diseases by acting as a miRNA sponge to indirectly regulate the expression of miRNA target ...
Chen, Jianwei +23 more
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Mechanism and Role of circRNA in Occurrence and Development of Hepatocellular Carcinoma
Zhongliu Fangzhi Yanjiu, 2022 Hepatocellular carcinoma (HCC) is the most common pathological type of primary liver cancer, with high fatality rate. The pathogenesis of HCC is complex, and the specific occurrence and development mechanism is still in the exploratory stage.
ZHOU Hong +6 more
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Nature Reviews Molecular Cell Biology, 2020 Increased expression of the circular RNA generated by the sulfateless gene (circSfl), and of the protein it encodes, can extend the lifespan of flies.
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LncRNAs and CircRNAs in cancer
MedComm, 2022 AbstractIt is well known that noncoding RNAs (ncRNAs) cannot encode proteins, but they can play important regulatory roles in tumors by combining with proteins, RNAs, and DNAs. As more and more studies reveal the important roles and underlying mechanisms of long noncoding RNAs (lncRNAs) and circular RNAs (circRNAs) in cancer, their huge application ...
Xin Yin +5 more
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