Results 51 to 60 of about 34,489 (213)

Role of circRNA in E3 Modification under Human Disease

, 2022
Circular RNA (circRNA) is often regarded as a special kind of non-coding RNA, involved in the regulation mechanism of various diseases, such as tumors, neurological diseases, and inflammation. In a broad spectrum of biological processes, the modification
Wang, Ting, Gao, Jiawen, Dai, Hui, Jiawen Gao, Zishuo Chen, Chao Zhang, Chen, Zishuo, Zhang, Chao, Minkai Song, Hui Dai, Ting Wang, Lin, Fei, Fei Lin, Song, Minkai   +13 more
core   +1 more source

The Potential Role of hsa_circ_0004214 as a Biomarker for Breast Cancer Prognosis [PDF]

Journal of Epigenetics
Breast cancer is the most important cause of cancer-related death among women. Finding cancer management biomarkers may improve cancer management strategies, patient outcomes, and quality of life.
Marzieh Beikzadeh, Mahdieh Salimi
doaj   +1 more source

Nucleotide-level prediction of CircRNA-protein binding based on fully convolutional neural network [PDF]

, 2023
Introduction: CircRNA-protein binding plays a critical role in complex biological activity and disease. Various deep learning-based algorithms have been proposed to identify CircRNA-protein binding sites.
Lin Yuan, Zhen Shen, SiGuo Wang, ShuJun Zhao, Wei Liu, QinHu Zhang   +5 more
core   +1 more source

Classification of RNA-Seq samples using circRNA expression

, 2018
Classification of RNA-Seq samples using circRNA ...
Carmen Gómez Valenzuela, Gómez-Valenzuela, Carmen   +1 more
core   +1 more source

Experimental validation of circRNA candidates.

, 2023
(A) Schematics of the biogenesis of circRNA candidates and gene structure of their host genes. Black line represents intron, whereas rectangle indicates exon.
Yulan Chen (1788139), Ying Zhou (25031), Jinbao Gu (217536), Peiwen Liu (3518645), Lu Yang (30847), Yonghui Gao (102566), Xiaoguang Chen (187869)   +6 more
core   +1 more source

Challenges and opportunities for circRNA identification and delivery

, 2023
Circular RNAs (circRNAs) are evolutionarily conserved noncoding RNAs with tissue-specific expression patterns, and exert unique cellular functions that have the potential to become biomarkers in therapeutic applications. Therefore, accurate and sensitive
Cheng, Zeneng, Ying Huang, Chuanpin Chen, Qubo Zhu, Zeng, Zhuoer, Zeneng Cheng, Jiani Dong, Dong, Jiani, Huang, Ying, Chen, Chuanpin, Zhu, Qubo, Zhuoer Zeng   +11 more
core   +1 more source

Circular RNA CircPRMT5 Accelerates Proliferation and Invasion of Papillary Thyroid Cancer Through Regulation of miR-30c/E2F3 Axis

Cancer Management and Research, 2020
Cheng Xue,1 Yi Cheng,1 Jinyou Wu,1 Kongliang Ke,2 Chundi Miao,2 Enfu Chen,1 Luqing Zhang2 1Department of Endocrinology, Wenling First People’s Hospital, Wenling 317500, People’s Republic of China; 2Department of Anorectal Surgery, Ningbo ...
Xue C, Cheng Y, Wu J, Ke K, Miao C, Chen E, Zhang L   +6 more
doaj  

Construction of a circRNA-Mediated ceRNA Network Reveals Novel Biomarkers for Aortic Dissection

International Journal of General Medicine, 2022
De-Bin Liu,1,* You-Fu He,2– 4,* Gui-Jian Chen,1 Hua Huang,1 Xu-Ling Xie,1 Wan-Jun Lin,1 Zhi-Jian Peng1 1Department of Cardiology, The Second People’s Hospital of Shantou, Shantou, Guangdong Province, People’s Republic of China; 2Department of ...
Liu DB, He YF, Chen GJ, Huang H, Xie XL, Lin WJ, Peng ZJ   +6 more
doaj  

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

Advanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang, Ziyao Wang, Dongyue Zuo, Zhaowen Su, Bowen Song, Jiamin Gao, Yizhou Zhang, Ruiting Zhao, Linjie Sun, Mengdi Li, Yirui Fan, Dandan Geng, Lei Wang   +12 more
wiley   +1 more source

Construction of a ceRNA network to reveal a vascular invasion associated prognostic model in hepatocellular carcinoma

Open Medicine, 2023
The aim of this study is to explore the prognostic value of vascular invasion (VI) in hepatocellular carcinoma (HCC) by searching for competing endogenous RNAs (ceRNA) network and constructing a new prognostic model for HCC.
Liu Yun, Yang Lu, Yu Mengsi, Huang Fen, Zeng Jiangzheng, Lu Yanda, Yang Changcheng   +6 more
doaj   +1 more source