Results 141 to 150 of about 45,661 (289)
Respiratory virus mRNA vaccines: mRNA Design, clinical studies, and future challenges
Animal Models and Experimental Medicine, EarlyView.Abstract Respiratory infectious diseases frequently erupt on a global scale, with RNA viruses, such as SARS‐CoV‐2, RSV, and influenza viruses, posing challenges to vaccine development due to their high mutation rates. Traditional vaccine development cycles are lengthy and struggle to keep pace with rapidly evolving viruses, whereas messenger RNA (mRNA)
Linlin Zheng, Han Feng
wiley +1 more source
Recent advances in malaria genomics and epigenomics [PDF]
, 2016 Malaria continues to impose a significant disease burden on low- and middle-income countries in the tropics. However, revolutionary progress over the last 3 years in nucleic acid sequencing, reverse genetics, and post-genome analyses has generated step ...
Kirchner, Sebastian +2 more
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Advances in miRNA research: Unraveling the complexities of gene regulation
Animal Models and Experimental Medicine, EarlyView.Overview of miRNA‐mediated regulation in key biological processes. This illustration offers a comprehensive view of the diverse functions that microRNAs perform in governing various biological processes, highlighting their profound significance within the complex web of gene expression and cellular function.
Jiawei Zheng, Guoqing Zhang, Linzhu Ren
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Programmable biomaterials for dynamic and responsive drug delivery [PDF]
, 2016 Biomaterials are continually being designed that enable new methods for interacting dynamically with cell and tissues, in turn unlocking new capabilities in areas ranging from drug delivery to regenerative medicine. In this review, we explore some of the
Almquist, BD, Kiani, MT, Stejskalova, A
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Noncoding RNAs in Host–Microbiota Interaction
Animal Research and One Health, EarlyView.The intricate interplay between gut microbiota and the host exerts a profound impact on host biological processes and disease development. This review highlights the pivotal role of noncoding RNAs (ncRNAs) in this interaction. Host ncRNAs regulate gene expression and microbiota composition, whereas microbial small RNAs (sRNAs) modulate host gene ...
Ziyi Zhao +7 more
wiley +1 more source
Journal of Inflammation Research, 2023 Zheng-Dao Mao,1,* Zhi-Guang Liu,1,* Yan Qian,1 Yu-Jia Shi,1 Lian-Zheng Zhou,1 Qian Zhang,1 Chun-Jian Qi2 1Department of Respiratory and Critical Care Medicine, Affiliated Changzhou No. 2 People’s Hospital of Nanjing Medical University, Changzhou,
Mao ZD +6 more
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Epigenetic Associations between lncRNA/circRNA and miRNA in Hepatocellular Carcinoma
Cancers, 2020 Simple Summary Non-coding RNAs such as microRNAs, long non-coding RNAs, and circular RNAs contribute to the development and progression of hepatocellular carcinoma through epigenetic association.
Tae-Su Han, K. Hur, Hyun-soo Cho, H. Ban
semanticscholar +1 more source
Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis
BMEMat, EarlyView.This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang +6 more
wiley +1 more source
Plasmatic circRNA Predicting the Occurrence of Human Glioblastoma
Cancer Management and Research, 2020 Ainian Chen,1 Lingling Zhong,1 Keju Ju,1 Ting Lu,1 Jia Lv,2 Hua Cao1 1Department of Neurology, The Affiliated Huai’an No.1 People’s Hospital of Nanjing Medical University, Huai’an, Jiangsu 223300, People’s Republic of China ...
Chen A, Zhong L, Ju K, Lu T, Lv J, Cao H
doaj
Emerging Concepts and Challenges in Rheumatoid Arthritis Gene Therapy
Biomedicines, 2020 Rheumatoid arthritis (RA) is a systemic inflammatory joint disease affecting about 1% of the population worldwide. Current treatment approaches do not ensure a cure for every patient.
Andrei A. Deviatkin +6 more
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