Results 191 to 200 of about 45,661 (289)

Rewriting the MASLD‐associated hepatocellular carcinoma script: Targeting epigenetics and metabolism

open access: yesInternational Journal of Cancer, Volume 157, Issue 10, Page 1991-2003, 15 November 2025.
Abstract Abnormal epigenetic patterns are crucial for the progression of metabolic‐associated steatotic liver disease (MASLD) and hepatocellular carcinoma (HCC) development. Recent research focused on the interplay between epigenetics and altered metabolic pathways in HCC from MASLD, suggesting that the reversibility of epigenetic changes offers ...
Chiara Aiello   +7 more
wiley   +1 more source

The prognostic potential of RNA in stage II colon cancer: Insights from a screened multicenter population‐based cohort study

open access: yesInternational Journal of Cancer, Volume 157, Issue 8, Page 1746-1755, 15 October 2025.
What's New? Patients with stage II colon cancer exhibit considerable variation in prognosis. Consequently, decisions regarding the necessity of adjuvant chemotherapy in this population often rely on imperfect high‐risk criteria. Here, the authors developed a novel RNA‐based risk score, using NanoString nCounter technology, to stratify recurrence risk ...
Ulrik Korsgaard   +8 more
wiley   +1 more source

A promising frontier of circulating messenger RNA in liquid biopsy: From mechanisms to clinical applications

open access: yesInternational Journal of Cancer, Volume 157, Issue 8, Page 1519-1537, 15 October 2025.
Abstract Liquid biopsy can revolutionize cancer patient management as repeated sampling allows real‐time monitoring of disease progression and response to treatment. The circulating transcriptome represents a rich source of potential cancer biomarkers, including coding and non‐coding RNAs.
Mengqian Li   +7 more
wiley   +1 more source

Hsa_circRNA_0101125 Promotes Proliferation, Migration, and Invasion of Esophageal Squamous Cell Carcinoma via miR‐143‐3p/ZNF148 Axis

open access: yesThe FASEB Journal, Volume 39, Issue 19, 15 October 2025.
hsa_circRNA_0101125 promotes esophageal squamous cell carcinoma progression by sponging miR‐143‐3p and upregulating ZNF148 expression. This regulatory axis enhances tumor cell proliferation, migration, and invasion, likely by modulating EMT‐related markers including E‐cadherin and Vimentin.
Hao Chen   +6 more
wiley   +1 more source

Mapping the Metastatic Landscape: A Population‐Based Cohort Study for Prognostic Insights Into Newly Diagnosed Stage IV Breast Cancer Cases

open access: yesCancer Innovation, Volume 4, Issue 5, October 2025.
This study represents comprehensive analysis of metastasis' anatomical distribution and prognosis in breast cancer, offering invaluable insights into metastatic tendencies and characteristics. ABSTRACT Background Breast cancer is the most common malignancy and a leading cause of cancer‐related deaths among women worldwide.
Xiangyi Kong   +8 more
wiley   +1 more source

Roles of miR‐181 Family Members in OSCC: Implications for Therapy and Diagnostics

open access: yesCancer Medicine, Volume 14, Issue 19, October 2025.
ABSTRACT Oral squamous cell carcinoma (OSCC) is a common and aggressive form of head and neck cancer, frequently associated with smoking, alcohol consumption, and HPV infection. MicroRNAs (miRNAs) are small, non‐coding RNA transcripts that play significant roles in cancer initiation and progression.
Alexandra Iulia Aghiorghiesei   +7 more
wiley   +1 more source

Comprehensive analysis of differentially expressed circRNAs revealed a ceRNA network in pancreatic ductaladenocarcinoma

open access: yesArchives of Medical Science, 2019
Jin-Zhe Zhou   +5 more
doaj   +1 more source

Hsa_circ_0005325 Regulates the Proliferation, Apoptosis, Colony Formation, Migration, and Angiogenesis‐Promoting Behavior of Oral Squamous Cell Carcinoma Cells Through the miR‐433‐3p/HMGA2 Axis

open access: yesClinical and Experimental Dental Research, Volume 11, Issue 5, October 2025.
ABSTRACT Objective To explore the mechanism by which hsa_circ_0005325 affects the proliferation, apoptosis, colony formation, migration, and angiogenesis‐promoting behavior of oral squamous cell carcinoma cells through the miR‐433‐3p/HMGA2 axis. Material and Methods qRT‒PCR was used to measure the expression of hsa_circ_0005325 in SCC25 and CAL‐27 ...
Zhihan Lin   +5 more
wiley   +1 more source

CircRNA-derived pseudogenes [PDF]

open access: yesCell Research, 2016
Ling-Ling Chen   +7 more
openaire   +3 more sources

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