Results 191 to 200 of about 45,661 (289)
Rewriting the MASLD‐associated hepatocellular carcinoma script: Targeting epigenetics and metabolism
Abstract Abnormal epigenetic patterns are crucial for the progression of metabolic‐associated steatotic liver disease (MASLD) and hepatocellular carcinoma (HCC) development. Recent research focused on the interplay between epigenetics and altered metabolic pathways in HCC from MASLD, suggesting that the reversibility of epigenetic changes offers ...
Chiara Aiello+7 more
wiley +1 more source
What's New? Patients with stage II colon cancer exhibit considerable variation in prognosis. Consequently, decisions regarding the necessity of adjuvant chemotherapy in this population often rely on imperfect high‐risk criteria. Here, the authors developed a novel RNA‐based risk score, using NanoString nCounter technology, to stratify recurrence risk ...
Ulrik Korsgaard+8 more
wiley +1 more source
Abstract Liquid biopsy can revolutionize cancer patient management as repeated sampling allows real‐time monitoring of disease progression and response to treatment. The circulating transcriptome represents a rich source of potential cancer biomarkers, including coding and non‐coding RNAs.
Mengqian Li+7 more
wiley +1 more source
hsa_circRNA_0101125 promotes esophageal squamous cell carcinoma progression by sponging miR‐143‐3p and upregulating ZNF148 expression. This regulatory axis enhances tumor cell proliferation, migration, and invasion, likely by modulating EMT‐related markers including E‐cadherin and Vimentin.
Hao Chen+6 more
wiley +1 more source
This study represents comprehensive analysis of metastasis' anatomical distribution and prognosis in breast cancer, offering invaluable insights into metastatic tendencies and characteristics. ABSTRACT Background Breast cancer is the most common malignancy and a leading cause of cancer‐related deaths among women worldwide.
Xiangyi Kong+8 more
wiley +1 more source
Roles of miR‐181 Family Members in OSCC: Implications for Therapy and Diagnostics
ABSTRACT Oral squamous cell carcinoma (OSCC) is a common and aggressive form of head and neck cancer, frequently associated with smoking, alcohol consumption, and HPV infection. MicroRNAs (miRNAs) are small, non‐coding RNA transcripts that play significant roles in cancer initiation and progression.
Alexandra Iulia Aghiorghiesei+7 more
wiley +1 more source
The EV-TRACK summary add-on: integration of experimental information in databases to ensure comprehensive interpretation of biological knowledge on extracellular vesicles [PDF]
Dedeyne, Sandor+3 more
core +1 more source
ABSTRACT Objective To explore the mechanism by which hsa_circ_0005325 affects the proliferation, apoptosis, colony formation, migration, and angiogenesis‐promoting behavior of oral squamous cell carcinoma cells through the miR‐433‐3p/HMGA2 axis. Material and Methods qRT‒PCR was used to measure the expression of hsa_circ_0005325 in SCC25 and CAL‐27 ...
Zhihan Lin+5 more
wiley +1 more source
CircRNA-derived pseudogenes [PDF]
Ling-Ling Chen+7 more
openaire +3 more sources