Results 21 to 30 of about 45,661 (289)
Molecular Cell, 2017 Circular RNAs (circRNAs) are abundant and evolutionarily conserved RNAs of largely unknown function. Here, we show that a subset of circRNAs is translated in vivo. By performing ribosome footprinting from fly heads, we demonstrate that a group of circRNAs is associated with translating ribosomes.
Pamudurti, Nagarjuna Reddy +16 more
openaire +4 more sources
陆军军医大学学报, 2023 Objective To investigate the effects of intraperitoneal injection of islet amyloid polypeptide (IAPP) on the expression profiles of circular RNAs (circRNAs) and messenger RNAs (mRNAs) in the brain tissue of Alzheimer's disease (AD) mice and wild-type ...
HOU Mingliang +3 more
doaj +1 more source
Nature Communications, 2023 Circular RNAs are known to be linked to cancer regulation. Here, the authors identify a circular RNA signature associated with immune checkpoint response in melanoma. Circular RNAs (circRNAs) play important roles in the regulation of cancer. However, the
Yu Dong +12 more
semanticscholar +1 more source
Current Opinion in Genetics & Development, 2018 Exonic circular RNAs (circRNAs) are mostly generated from exons of protein-coding genes and, in many cases, are more abundant that the linear product from their hosting gene. Certain circRNAs are very abundant in the brain and in non-dividing cells; and many also show physiological-specific and tissue-specific expression.
Ines Lucia Patop +2 more
openaire +2 more sources
CircRNA Role and circRNA-Dependent Network (ceRNET) in Asthenozoospermia [PDF]
Frontiers in Endocrinology, 2020 The role of circRNA in reproduction is under investigation. CircRNAs are expressed in human testis, spermatozoa (SPZ), and seminal plasma. Their involvement in embryo development has also been suggested. Asthenozoospermia, a common cause of male infertility, is characterized by reduced or absent sperm motility in fresh ejaculate.
Francesco Manfrevola +8 more
openaire +4 more sources
International Journal on Biological Sciences, 2023 Circular RNAs (circRNAs) are covalently closed RNA structures that play multiple roles in tumorigenesis and progression. Compared with exon‒intron circRNAs, the biological functions and implications of intergenic circRNAs in human cancer are still poorly
Fei Long +22 more
semanticscholar +1 more source
The invasion of circRNAs [PDF]
RNA Biology, 2017 Single-stranded covalently closed circular RNA (circRNA) molecules come in many disguises, with different biogenesis mechanisms and functions.
Hansen, Thomas B., Kjems, Jørgen
openaire +4 more sources
Gastroenterology, 2023 BACKGROUND & AIMS Pancreatic ductal adenocarcinoma (PDAC) is one of the most fatal malignancies. Delayed manifestation of symptoms and the lack of specific diagnostic markers lead to diagnosing PDAC patients at advanced stages.
Caiming Xu +11 more
semanticscholar +1 more source
Combined exposure to noise and CO induces adverse male reproductive effects in rats
陆军军医大学学报, 2023 Objective To explore the male reproductive toxicity in rats caused by single or combined exposure to noise and carbon monoxide (CO) in closed cabin, and evaluate the joint effects and associated signal pathways.
LI Yingqing +4 more
doaj +1 more source
Circular Ribonucleic Acid Expression in Patient with Acne [PDF]
Egyptian Journal of Medical Research, 2022 Background: Acne is a common chronic skin disease with a multifactorial aetiology and pathogenesis. Recently, circular RNAs (circRNAs) have been identified as a key factor in regulating gene expression through circRNA–miRNA–mRNA networks in many ...
Abd-Elaziz El-Taweel +3 more
doaj +1 more source