Results 91 to 100 of about 31,091 (262)
CircRNAs in hematopoiesis and hematological malignancies [PDF]
Cell states in hematopoiesis are controlled by master regulators and by complex circuits of a growing family of RNA species impacting cell phenotype maintenance and plasticity.
Bonizzato A. +7 more
core +1 more source
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers due to its asymptomatic progression, late‐stage diagnosis, and treatment resistance. Efforts in early detection have centered on identifying imaging features and liquid biopsy biomarkers capable of detecting PDAC and its high‐grade precursors before clinical symptoms ...
Christine Worthington +105 more
wiley +1 more source
Roles of CircRNAs in Autoimmune Diseases [PDF]
Circular RNAs (circRNAs) are covalently linked single-stranded RNAs, compared to linear counterparts that are relatively abundant, conserved, stable, and specific. Previously, most studies have revealed that circRNAs function in gene expression processes and participate in the pathogenesis of cancers, cardiovascular diseases, and neurological diseases.
Xin Xia +4 more
openaire +3 more sources
Identification of Hub Gene TIMP1 and Relative ceRNAs Regulatory Network in Colorectal Cancer
Ya-Fei Qin,1,2 Guang-Ming Li,1,2 Grace Wang,3 De-Jun Kong,1,2 Hong-Da Wang,1,2 Yi-Ming Zhao,1,2 Jing-Peng Hao,4 Hong Qin,1,2 Da-Qing Sun,5 Hao Wang1,2 1Department of General Surgery, Tianjin Medical University General Hospital, Tianjin, People’s Republic
Qin YF +9 more
doaj
Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong +5 more
wiley +1 more source
Roles of circRNAs in the Tumorigenesis and Metastasis of HCC: A Mini Review
Yichen Liu, Lei Wang, Wen Liu Fujian Provincial Key Laboratory of Innovative Drug Target Research, School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, 361102, People’s Republic of ChinaCorrespondence: Yichen Liu; Wen Liu, Email yc-liu ...
Liu Y, Wang L, Liu W
doaj
Noncoding AUG circRNAs constitute an abundant and conserved subclass of circles
AUG circRNAs are highly abundant and conserved with an Alu -independent mode of biogenesis. Although AUG circRNAs contain the N-terminal ORFs, no evidence supports translation of these circRNAs.
Lotte VW Stagsted +3 more
doaj +1 more source
The circRNAs-miRNAs-CADM1 network.
The circRNAs-miRNAs-CADM1 network.
Qingyu Wang (697246) +8 more
core +1 more source
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little +12 more
wiley +1 more source

