Results 71 to 80 of about 25,680 (233)
Angewandte Chemie, EarlyView.Eine klickbare, photogeschützte 5′‐Kappe (CyCliCap) zur Herstellung von zyklischer, Click‐Cap enthaltender mRNA (Cyclic Click Cap‐mRNA), die bis zur Bestrahlung beachtlich stabil und translational stumm ist, ermöglicht die Aktivierung der Translation in Zellen zu späten Zeitpunkten mittels Lichts. ZUSAMMENFASSUNG mRNA ist eine neue Impfstofftechnologie
Bayram Terzi +6 more
wiley +1 more source
Identification of Hub Gene TIMP1 and Relative ceRNAs Regulatory Network in Colorectal Cancer
Therapeutics and Clinical Risk Management, 2021 Ya-Fei Qin,1,2 Guang-Ming Li,1,2 Grace Wang,3 De-Jun Kong,1,2 Hong-Da Wang,1,2 Yi-Ming Zhao,1,2 Jing-Peng Hao,4 Hong Qin,1,2 Da-Qing Sun,5 Hao Wang1,2 1Department of General Surgery, Tianjin Medical University General Hospital, Tianjin, People’s Republic
Qin YF +9 more
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Expression profiles of circular RNAs in sheep skeletal muscle [PDF]
Asian-Australasian Journal of Animal Sciences, 2018 Objective Circular RNAs (circRNAs) are a newfound class of non-coding RNA in animals and plants. Recent studies have revealed that circRNAs play important roles in cell proliferation, differentiation, autophagy and apoptosis during development.
Yang Cao +14 more
doaj +1 more source
Roles of CircRNAs in Autoimmune Diseases [PDF]
Frontiers in Immunology, 2019 Circular RNAs (circRNAs) are covalently linked single-stranded RNAs, compared to linear counterparts that are relatively abundant, conserved, stable, and specific. Previously, most studies have revealed that circRNAs function in gene expression processes and participate in the pathogenesis of cancers, cardiovascular diseases, and neurological diseases.
Xin Xia +4 more
openaire +3 more sources
Circular Photocaged mRNA for Light‐induced Late‐stage Activation of Translation
Angewandte Chemie International Edition, EarlyView.A clickable photo‐caged 5′ cap (CyCliCap) allows to make Cyclic Click Cap‐containing mRNA (CyCliCap‐mRNA) which is remarkably stable and translationally muted until irradiated, allowing for late‐stage activation of translation in cells by light. ABSTRACT mRNA is a new medical modality as vaccine and raises hopes to become a protein replacement agent ...
Bayram Terzi +6 more
wiley +1 more source
Roles of circRNAs in the Tumorigenesis and Metastasis of HCC: A Mini Review
Cancer Management and Research, 2022 Yichen Liu, Lei Wang, Wen Liu Fujian Provincial Key Laboratory of Innovative Drug Target Research, School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, 361102, People’s Republic of ChinaCorrespondence: Yichen Liu; Wen Liu, Email yc-liu ...
Liu Y, Wang L, Liu W
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Noncoding AUG circRNAs constitute an abundant and conserved subclass of circles
Life Science Alliance, 2019 AUG circRNAs are highly abundant and conserved with an Alu -independent mode of biogenesis. Although AUG circRNAs contain the N-terminal ORFs, no evidence supports translation of these circRNAs.
Lotte VW Stagsted +3 more
doaj +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu +3 more
wiley +1 more source
Biological Reviews, EarlyView.ABSTRACT The complexity of breast cancer (BC) lung metastasis lies in the capacity of tumour cells to interact efficiently with distant organs to promote colonisation, a process that involves the sophisticated coordination of inherent cellular plasticity and the remodelling of the distant microenvironment.
Jian Lu +12 more
wiley +1 more source
hsa_circRNA_012515 Is Highly Expressed in NSCLC Patients and Affects Its Prognosis
Cancer Management and Research, 2020 Yunfeng Fu, 1,* Liang Huang, 2,* Hao Tang, 1 Rong Huang 1 1The Third Xiangya Hospital, Central South University, Changsha 410013, People’s Republic of China; 2Department of Urology, The First Affiliated Hospital of Nanchang University, Nanchang ...
Fu Y, Huang L, Tang H, Huang R
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