Results 111 to 120 of about 32,863 (251)
Invention of circRNA promoting RNA to specifically promote circRNA production
Nucleic Acids ResearchAbstract CircRNA, an essential RNA molecule involved in various biological functions and diseases, often exhibits decreased expression in tumor tissues, playing a role as a tumor suppressor, and suggesting therapeutic potential for cancer. However, current methods for promoting circRNA production are limited.
Zhilin He +5 more
openaire +2 more sources
Cancer Science, EarlyView.The proposed mechanistic model in this study. ABSTRACT Noncoding RNAs, including circular RNAs (circRNAs), have been demonstrated to play vital roles in tumorigenesis. Uncovering the functions of circRNAs in tumorigenesis and their underlying regulatory mechanisms may suggest new approaches to the development of novel diagnostic and therapeutic ...
Yanfeng Liu, Yanan Gao, Chuanli Zhao
wiley +1 more source
Cell Proliferation, EarlyView.A schematic diagram illustrating how 3′tiRNA‐GlyGCC promotes the endoplasmic reticulum stress (ERS) and proliferation in hypoxic pulmonary artery smooth muscle cells (PASMCs) by inhibiting the expression of myelin regulatory factor (Myrf), ultimately leading to pulmonary hypertension (PH).
Lixin Zhang +11 more
wiley +1 more source
A Highly Efficient Strategy for Overexpressing circRNAs
, 2018 Circular RNAs (circRNAs) constitute an emerging class of widespread, abundant, and evolutionarily conserved noncoding RNA. They play important and diverse roles in cell development, growth, and tumorigenesis, but functions of the majority of circRNAs ...
Simon J. Conn +7 more
core +1 more source
DataSheet1_Exosomal circRNAs: Emerging Players in Tumor Metastasis.PDF
, 2021 Metastasis is an important feature of malignant tumors, and is the primary cause of poor prognosis and treatment failure, in addition to representing a potentially fatal challenge for cancer patients.
Hao Zhou (136535) +4 more
core +1 more source
Genome-wide identification and functional analysis of circRNAs in Zea mays.
PLoS ONE, 2018 Circular RNAs (circRNAs) are a class of endogenous noncoding RNAs, which increasingly drawn researchers' attention in recent years as their importance in regulating gene expression at the transcriptional and post-transcriptional levels.
Baihua Tang +4 more
doaj +1 more source
Journal of Diabetes Investigation, EarlyView.The systematic review and meta‐analysis (Embase, PubMed, and Web of Science; up to August 2025) evaluated circulating noncoding RNAs (ncRNAs) as noninvasive early diagnostic biomarkers for diabetic retinopathy (DR). From 17 articles (24 studies, 1,983 DR patients vs 1,437 controls), a random‐effects model yielded pooled sensitivity of 0.81, specificity
Ting Zhang, Donghong Xu
wiley +1 more source
Differentially expressed circRNAs.
, 2023 ObjectiveSince circRNA can be utilized as a potential diagnostic marker for cancer, to explore the regulatory mechanism of colorectal cancer (CRC) using bioinformatics, the public database of circRNA was mined.MethodsCRC differentially expressed miRNAs ...
Lei Xu (78676) +3 more
core +1 more source
, 2023 Creative Biogene is a global biotechnology company devoting to offer high-quality service for customers. We provide a one stop solution for circRNA prediction, identification, preliminary screening, functional analysis and circRNA-miRNA/RBP interaction mechanism analysis to accelerate your biomarker discovery and drug development research. Supported by
openaire +2 more sources
Saliva Liquid Biopsy for Detection of Oral and Systemic Diseases
Journal of Periodontal Research, EarlyView.This Review summarizes and discusses the biological foundations and major classes of salivary biomarkers, outlines collection methods and analytical protocols for saliva‐based liquid biopsy, and technological convergences driven by multi‐omics approaches, artificial intelligence, and point‐of‐care devices in the application of oral and systemic ...
Irene Choi +10 more
wiley +1 more source