Results 101 to 110 of about 31,091 (262)
Interdisciplinary Medicine, EarlyView.Inspired by the role of Mg2+ in stabilizing RNA secondary structures, we developed a one‐pot biomimetic mineralization method for synthesizing a circular RNA‐based nanovaccine (circRNA@FAiNVac) that integrates formulation and adjuvant functions. This nanovaccine exhibits potent immunostimulatory activation enabling multimodal immune responses and ...
Liangru Lin +10 more
wiley +1 more source
hsa_circRNA_012515 Is Highly Expressed in NSCLC Patients and Affects Its Prognosis
Cancer Management and Research, 2020 Yunfeng Fu, 1,* Liang Huang, 2,* Hao Tang, 1 Rong Huang 1 1The Third Xiangya Hospital, Central South University, Changsha 410013, People’s Republic of China; 2Department of Urology, The First Affiliated Hospital of Nanchang University, Nanchang ...
Fu Y, Huang L, Tang H, Huang R
doaj
International Journal of Nanomedicine, 2023 Yu-Guo Yuan,1,2,* Ya-Xin Zhang,1,* Song-Zi Liu,1,* Abu Musa Md Talimur Reza,3 Jia-Lin Wang,1,2 Ling Li,1,2 He-Qing Cai,1,2 Ping Zhong,1 Il-Keun Kong4 1College of Veterinary Medicine, Yangzhou University, Yangzhou, People’s Republic of China ...
Yuan YG +8 more
doaj
The novel roles of circRNAs in human cancer
, 2019 Covalently closed single-stranded circular RNAs (circRNAs) consist of introns or exons and are widely present in eukaryotic cells. CircRNAs generally have low expression levels and relatively stable structures compared with messenger RNAs (mRNAs), most ...
Qingfeng Shang +3 more
core +1 more source
Interdisciplinary Medicine, EarlyView.Extracellular vesicles play pivotal roles in both healthy hematopoiesis and hematologic malignancies. They not only regulate hematopoietic stem cell fitness but also drive cancer progression and drug resistance. Their clinical potential spans from serving as non‐invasive biomarkers to acting as innovative therapeutic platforms and drug delivery ...
Fengyu Chen +5 more
wiley +1 more source
Cancer Management and Research, 2020 Xiao Liu,1,* Hao Tang,1,* Jing Liu,1 Xiang Wang2 1The Third Xiangya Hospital of Central South University, Changsha 410013, People’s Republic of China; 2Department of Hematology, First Affiliated Hospital of Anhui Medical University, Hefei 230022 ...
Liu X, Tang H, Liu J, Wang X
doaj
Molecular Therapy: Nucleic Acids, 2017 Circular RNAs (circRNAs) are involved in the development of various diseases; however, knowledge on circRNAs in osteoarthritis (OA) is limited. This study aims to identify circRNA expression in different regions affected by OA and to explore the function
Qiang Liu +6 more
doaj +1 more source
DataSheet1_Exosomal circRNAs: Emerging Players in Tumor Metastasis.PDF
, 2021 Metastasis is an important feature of malignant tumors, and is the primary cause of poor prognosis and treatment failure, in addition to representing a potentially fatal challenge for cancer patients.
Hao Zhou (136535) +4 more
core +1 more source
RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment
Precision Medical Sciences, EarlyView.This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run +7 more
wiley +1 more source
Invention of circRNA promoting RNA to specifically promote circRNA production
Nucleic Acids ResearchAbstract CircRNA, an essential RNA molecule involved in various biological functions and diseases, often exhibits decreased expression in tumor tissues, playing a role as a tumor suppressor, and suggesting therapeutic potential for cancer. However, current methods for promoting circRNA production are limited.
Zhilin He +5 more
openaire +2 more sources