Results 21 to 30 of about 385,110 (187)

Constitutively active microglial populations limit anorexia induced by the food contaminant deoxynivalenol

Journal of Neuroinflammation, 2022
Microglia are involved in neuroinflammatory processes during diverse pathophysiological conditions. To date, the possible contribution of these cells to deoxynivalenol (DON)-induced brain inflammation and anorexia has not yet been evaluated.
Stéphanie Gaige, Rym Barbouche, Manon Barbot, Sarah Boularand, Michel Dallaporta, Anne Abysique, Jean-Denis Troadec   +6 more
doaj   +1 more source

Circumventricular organs: a novel site of neural stem cells in the adult brain. [PDF]

Mol Cell Neurosci, 2009
Neurogenesis in the adult mammalian nervous system is now well established in the subventricular zone of the anterolateral ventricle and subgranular zone of the hippocampus.
Bennett L, Yang M, Enikolopov G, Iacovitti L.   +3 more
europepmc   +2 more sources

IMMUNOHISTOCHEMICAL EXPRESSION OF MONOCARBOXYLATE TRANSPORTER 1&4 IN TANYCYTE–LIKE CELLS OF THE SULCUS MEDIANUS ORGANUM

The Iraqi Journal of Medical Sciences, 2019
Background: Circumventricular organs (CVOs) are specialized structures border the brain ventricles and lack the blood-brain barrier. These CVOs are lined by specialized ependymal cells (ECs) called tanycyte.
Haider F. Jawad, Muthanna A. Al-Kaabi, Anam R. Al-Salihi   +2 more
doaj   +6 more sources

LPS Primes Brain Responsiveness to High Mobility Group Box-1 Protein

Pharmaceuticals, 2021
High mobility group box (HMGB)1 action contributes to late phases of sepsis, but the effects of increased endogenous plasma HMGB1 levels on brain cells during inflammation are unclear.
Verena Peek, Lois M. Harden, Jelena Damm, Ferial Aslani, Stephan Leisengang, Joachim Roth, Rüdiger Gerstberger, Marita Meurer, Maren von Köckritz-Blickwede, Sabine Schulz, Bernhard Spengler, Christoph Rummel   +11 more
doaj   +1 more source

Thirst and blood pressure regulation in a novel angiotensin II receptor type 1a knockout rat. [PDF]

Physiol Rep
Regulation of arterial blood pressure (ABP) is largely preserved in angiotensin II receptor 1a knock‐out (Agtr1a−/−) rats. However, deletion of Agtr1a attenuates thirst in response to AngII and hypotension but not intracellular dehydration. Abstract Angiotensin II (AngII) plays a pivotal role in body fluid balance through AngII type 1 receptors (Agtr1)
Ferreira CB, Stocker SD.
europepmc   +2 more sources

LOCALIZATION OF TIGHT JUNCTIONS BETWEEN TANYCYTE-LIKE CELLS OF THE SULCUS MEDIANUS ORGANUM IN RAT BRAIN

The Iraqi Journal of Medical Sciences, 2017
Background: Tanycytes are highly specialized ependymal cells (ECs) that line the regions of circumventricular organs (CVOs) where the blood-brain barrier is absent.
Fadhil H. Ahmed, Muthanna A. Al-Kaabi, Sarmad E. Al-Marsoummi, Hayder A. Al-Aubaidy   +3 more
doaj   +6 more sources

The neuroactive neurosteroid Dehydroepiandrosterone Sulfate (DHEAS) modulates the serotonergic system within the dorsal Raphe nucleus and the cerebrospinal fluid release of Reissner’s fiber in rat

Comptes Rendus Biologies, 2020
Dehydroepiandrosterone sulfate (DHEAS) exerts important functions in the nervous system, such as modulation of neuronal death, brain development, cognition and behavior.
El Hiba, Omar, Draoui, Ahmed, Gamrani, Halima   +2 more
doaj   +1 more source

Central interaction between nitric oxide, lactate and glial cells to modulate water and sodium intake in rats

Brain Research Bulletin, 2022
The ''astrocyte-to-neuron lactate shuttle'' (ANLS) mechanism is part of the central inhibitory pathway to modulate sodium intake. An interaction between the GABAergic neurons and nitric oxide (NO) in the subfornical organ (SFO) in salt-appetite ...
Francineide Fernandes-Costa, Atalia Ferreira de Lima Flôr, Maria Socorro França-Silva, Camille de Moura Balarini, José Luiz de Brito Alves, Valdir de Andrade Braga, Josiane Campos Cruz   +6 more
doaj   +1 more source

Anatomical Organization of the Rat Subfornical Organ

Frontiers in Cellular Neuroscience, 2021
The subfornical organ (SFO) is a sensory circumventricular organ located along the anterodorsal wall of the third ventricle. SFO lacks a complete blood-brain barrier (BBB), and thus peripherally-circulating factors can penetrate the SFO parenchyma. These
Amirah-Iman Hicks, Simona Kobrinsky, Suijian Zhou, Jieyi Yang, Masha Prager-Khoutorsky   +4 more
doaj   +1 more source

Neuro-Inflammatory Response and Brain-Peripheral Crosstalk in Sepsis and Stroke

Frontiers in Immunology, 2022
Despite recent therapeutic advances, ischemic stroke is still a leading cause of death and disability. There is renewed attention on peripheral inflammatory signaling as a way of modulating the post-ischemic neuro-inflammatory process.
Lena Bourhy, Aurélien Mazeraud, Aurélien Mazeraud, Fernando A. Bozza, Fernando A. Bozza, Guillaume Turc, Pierre-Marie Lledo, Tarek Sharshar   +7 more
doaj   +1 more source