Results 41 to 50 of about 5,707 (163)

Circulating neutrophil extracellular traps in cats with hypertrophic cardiomyopathy and cardiogenic arterial thromboembolism

Journal of Veterinary Internal Medicine, 2023
Background Cats with hypertrophic cardiomyopathy (HCM) are at risk of cardiogenic arterial thromboembolism (CATE). Neutrophil extracellular traps (NETs) may be a potential biomarker and therapeutic target for cardiomyopathy in cats. Hypothesis/Objectives
Ronald H. L. Li, Arianne Fabella, Nghi Nguyen, Joanna L. Kaplan, Eric Ontiveros, Joshua A. Stern   +5 more
doaj   +1 more source

The Diagnostic Utility of Natural Killer Cell Subsets in Deep Vein Thrombosis

Vascular Health and Risk Management, 2023
Alshaymaa M Alhabibi,1 Maisa A Wahab,2 Ahmed Khairy Sakr,2 Samar M Abd El-Hamid,1 Mohamed Yahia Zakaria,3 Azza Ali Althoqapy,4 Hanaa Mohammed Eid El Sayed,5 Sammar Ahmed Kasim,5 Hanan F Ibrahim,4 Ola I Saleh,6 Howida A Ahmed,6 Alaa H Sayed,7 Mahmoud ...
Alhabibi AM, Wahab MA, Sakr AK, Abd El-Hamid SM, Zakaria MY, Althoqapy AA, El Sayed HME, Kasim SA, Ibrahim HF, Saleh OI, Ahmed HA, Sayed AH, Lotfy M   +12 more
doaj  

GnRH Stimulates Peptidylarginine Deiminase Catalyzed Histone Citrullination in Gonadotrope Cells [PDF]

Molecular Endocrinology, 2016
Peptidylarginine deiminase (PAD) enzymes convert histone tail arginine residues to citrulline resulting in chromatin decondensation. Our previous work found that PAD isoforms are expressed in female reproductive tissues in an estrous cycle-dependent fashion, but their role in the anterior pituitary gland is unknown. Thus, we investigated PAD expression
Khan, Shaihla A., Edwards, Brian S., Muth, Aaron, Thompson, Paul R, Cherrington, Brian D., Navratil, Amy M.   +5 more
openaire   +3 more sources

Neutrophil Extracellular Traps Formation and Citrullinated Histones 3 Levels in Patients with Kawasaki Disease [PDF]

Iranian Journal of Immunology, 2023
Background: Kawasaki disease (KD) is a vasculitis associated with vascular injury and autoimmune response. Inflammatory factors stimulate neutrophils to produce web-like structures called neutrophil extracellular traps (NETs).
Jing Hu, Wei Qian, Tianhe Wang, Jingjing Ling, Yingzuo Shi   +4 more
doaj   +1 more source

Progression on Citrullination of Proteins in Gastrointestinal Cancers

Frontiers in Oncology, 2019
The citrullination modification (Cit) of proteins has received increasing attention in recent years. This kind of protein modification was first discovered in autoimmune diseases such as rheumatoid arthritis.
Shuzheng Song, Yingyan Yu
doaj   +1 more source

Extracellular histones in lung dysfunction: a new biomarker and therapeutic target?

Pulmonary Circulation, 2020
Extracellular histones released from injured or dying cells following trauma and other severe insults can act as potent damage-associated molecular patterns.
Pratap Karki, Konstantin G. Birukov, Anna A. Birukova   +2 more
doaj   +1 more source

Computational Methodologies for the in vitro and in situ Quantification of Neutrophil Extracellular Traps

Frontiers in Immunology, 2019
Neutrophil extracellular traps (NETs) are a neutrophil defensive mechanism where chromatin is expelled together with antimicrobial proteins in response to a number of stimuli. Even though beneficial in many cases, their dysfunction has been implicated in
Shane V. van Breda, Shane V. van Breda, Lenka Vokalova, Claire Neugebauer, Simona W. Rossi, Sinuhe Hahn, Paul Hasler   +6 more
doaj   +1 more source

Histone citrullination by PADI4 is required for HIF-dependent transcriptional responses to hypoxia and tumor vascularization [PDF]

Science Advances, 2021
Histone citrullination by PADI4 is required for hypoxia-induced gene expression.
Yufeng Wang, Yajing Lyu, Kangsheng Tu, Qiuran Xu, Yongkang Yang, Shaima Salman, Nguyet Le, Haiquan Lu, Chelsey Chen, Yayun Zhu, Ru Wang, Qingguang Liu, Gregg L. Semenza   +12 more
openaire   +2 more sources

Role of the lipoxin A4 receptor in the development of neutrophil extracellular traps in Leishmania infantum infection

Parasites & Vectors, 2019
Background Neutrophils play an immunomodulatory role through the release of neutrophil extracellular traps (NETs). NETs are released in response to Leishmania infection, but the mechanism of NET extrusion has not been elucidated.
Furong Wei, Wenci Gong, Junyun Wang, Yuetao Yang, Jianxiu Liu, Yanjuan Wang, Jianping Cao   +6 more
doaj   +1 more source

Neutrophil extracellular traps in stored canine red blood cell units

Journal of Veterinary Internal Medicine, 2020
Background Neutrophil extracellular traps (NETs), webs of DNA and citrullinated histones extruded from activated neutrophils cause transfusion‐related acute lung injury.
Erin R. McQuinn, Stephanie A. Smith, Austin K. Viall, Chong Wang, Dana N. LeVine   +4 more
doaj   +1 more source