Results 31 to 40 of about 660,625 (335)

Complement-coagulation cross-talk: a potential mediator of the physiological activation of complement by low pH

open access: yesFrontiers in Immunology, 2015
The complement system is a major constituent of the innate immune system. It not only bridges innate and adaptive arms of the immune system but also links the immune system with the coagulation system.
Hany Ibrahim Kenawy   +2 more
doaj   +1 more source

Identification of an alternative G{alpha}q-dependent chemokine receptor signal transduction pathway in dendritic cells and granulocytes [PDF]

open access: yes, 2007
CD38 controls the chemotaxis of leukocytes to some, but not all, chemokines, suggesting that chemokine receptor signaling in leukocytes is more diverse than previously appreciated.
Borchers, Michael T.   +7 more
core   +2 more sources

Decreased Ficolin-3-mediated Complement Lectin Pathway Activation and Alternative Pathway Amplification During Bacterial Infections in Patients With Type 2 Diabetes Mellitus

open access: yesFrontiers in Immunology, 2019
Bacterial infections are frequent and severe in patients with diabetes mellitus. Whether diabetes per se induces functional alterations in the complement system hampering activation during infection is unknown.
László József Barkai   +6 more
doaj   +1 more source

Complement activation and protein adsorption by carbon nanotubes [PDF]

open access: yes, 2006
As a first step to validate the use of carbon nanotubes as novel vaccine or drug delivery devices, their interaction with a part of the human immune system, complement, has been explored.
Flahaut, Emmanuel   +5 more
core   +2 more sources

Complement in the Initiation and Evolution of Rheumatoid Arthritis

open access: yesFrontiers in Immunology, 2018
The complement system is a major component of the immune system and plays a central role in many protective immune processes, including circulating immune complex processing and clearance, recognition of foreign antigens, modulation of humoral and ...
V. Michael Holers, Nirmal K. Banda
doaj   +1 more source

Carbamylation of immunoglobulin abrogates activation of the classical complement pathway [PDF]

open access: yesEuropean Journal of Immunology, 2014
Post‐translational modifications of proteins significantly affect their structure and function. The carbamylation of positively charged lysine residues to form neutral homoitrulline occurs primarily under inflammatory conditions through myeloperoxidase‐dependent cyanate (CNO−) formation.
Anders Dahl-Knudsen   +13 more
openaire   +8 more sources

Frustrated double ionization in two-electron triatomic molecules [PDF]

open access: yes, 2016
Using a semi-classical model, we investigate frustrated double ionization (FDI) in $\mathrm{D_3^+}$, a two-electron triatomic molecule, when driven by an intense, linearly polarized, near-infrared (800 nm) laser field.
Chen, A.   +3 more
core   +3 more sources

Is the Complement Protein C1q a Pro- or Anti-tumorigenic Factor? Bioinformatics Analysis Involving Human Carcinomas

open access: yesFrontiers in Immunology, 2019
C1q is the first subcomponent of the classical pathway of the complement system and belongs to the C1q/Tumor Necrosis Factor superfamily. C1q can perform a diverse range of immune and non-immune functions in a complement-dependent as well as -independent
Alessandro Mangogna   +11 more
doaj   +1 more source

The basal ganglia, the ideal machinery for the cost-benefit analysis of action plans [PDF]

open access: yes, 2013
Basal ganglia dysfunction causes profound movement disorders, often attributed to imbalance between direct and indirect pathway activity in the sensorimotor basal ganglia.
Hwang, Eun Jung
core   +2 more sources

Peptide inhibitor of complement C1 (PIC1), a novel suppressor of classical pathway activation: mechanistic studies and clinical potential

open access: yesFrontiers in Immunology, 2014
The classical pathway of complement plays multiple physiological roles including modulating immunological effectors initiated by adaptive immune responses as well as an essential homeostatic role in the clearance of damaged self-antigens.
Julia A Sharp   +5 more
doaj   +1 more source

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