Results 241 to 250 of about 20,650 (306)

Role of claudin-6 in high-grade endometrial carcinoma: Implications for risk stratification and personalized treatment strategies. [PDF]

World J Clin Oncol
Cai C, Chen JM, Qiu ZX, Ren SQ.
europepmc   +1 more source

Metformin as a Multifaceted Therapeutic Agent for Gastrointestinal Diseases: Mechanisms, Clinical Efficacy, and Future Directions

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT The high prevalence of gastrointestinal (GI) diseases and their significant impact on the quality of life require new therapeutic strategies. The development of novel therapeutic strategies should prioritize targeting the fundamental pathophysiological mechanisms underlying these diseases, including inflammation, cellular proliferation, and ...
Sayedeh Azimeh Hosseini, Hassan Valadbeigi, Seyedeh Mahdieh Khoshnazar, Saeed Khoshnood, Shahab Falahi, Delsuz Rezaee, Ali Hematian, Mohammad Hossein Haddadi   +7 more
wiley   +1 more source

Junctions, Transporters, and Interactions of Endothelial Cells: Regulation by Ethanol. [PDF]

Int J Mol Sci
Mandyam CD, Vandekerkhoff A, Jung S, Kharidia D, Ponomarev I, Kisby B.   +5 more
europepmc   +1 more source

Mechanism of Fluid Reabsorption in Kidney Proximal Tubule: Interplay Between Lateral Na+/K+‐ATPase and AQP1 and SGLT1 Mediated Water Fluxes

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aims The mechanism of isosmotic water reabsorption in the kidney proximal tubule, with a focus on the interaction between the lateral Na+/K+‐ATPase, apical water pathways mediated by AQP1 and SGLT1, and paracellular water flow through Claudin‐2. Methods A mathematical model of proximal tubular transport was used to compute coupled ion, solute,
Erik Hviid Larsen, Jens Nørkær Sørensen   +1 more
wiley   +1 more source

Proximal TGF-β Signaling in Chronic Injury: from a notorious fibrotic factor to a repair ally. [PDF]

Pflugers Arch
Nlandu Khodo S.
europepmc   +1 more source

Modulation of KATP channels by diazoxide preserves mitochondrial function and barrier integrity under staurosporine‐induced epithelial stress

British Journal of Pharmacology, Volume 183, Issue 12, Page 3213-3233, June 2026.
Background and Purpose Intestinal barrier dysfunction caused by mitochondrial stress, oxidative damage and apoptosis, are hallmarks of dysbiosis‐associated gastrointestinal (GI) disorders. Staurosporine causes downstream features of dysbiosis‐induced epithelial damage.
Fatima Maqoud, Eleonora Malerba, Simona Drago, Antonella Orlando, Domenica Mallardi, Nicoletta De Lucia, Marina Antonacci, Annamaria Di Turi, Domenico Tricarico, Francesco Russo   +9 more
wiley   +1 more source

Effect of chronic heat stress on duodenal epithelial barrier integrity in low- and high-water-efficient broiler chickens. [PDF]

Front Physiol
Liu L, Greene ES, Roach B, Orlowski S, Dridi S.   +4 more
europepmc   +1 more source

Genomic and transcriptomic heterogeneity in metaplastic carcinomas of the breast [PDF]

, 2017
et al,, Maher, Christopher A
core   +1 more source

A Novel Role of the Perineurium: Evidence for an Essential Function for Macrophage Maintenance and Increase in Isolated Peripheral Nerves

Journal of the Peripheral Nervous System, Volume 31, Issue 2, June 2026.
ABSTRACT Background and Aims It is an established view that the perineurium surrounding peripheral nerves fulfills pivotal barrier functions to protect nerve fibers from noxious agents of the nerve environment. Here we want to investigate whether the perineurium also influences other endoneurial cells, like macrophages.
Miriam Geldermann, Dennis Klein, Eva Maria Weiß, Rudolf Martini   +3 more
wiley   +1 more source

Role of Caveolae and Caveolin in Vascular Physiology and Pathology. [PDF]

J Am Heart Assoc
Zhang C, Hu W, Zhang J, Wang Z, Lu H.
europepmc   +1 more source