Results 251 to 260 of about 20,650 (306)

Triple‐Negative Breast Cancer Versus Non‐Triple‐Negative Breast Cancer: The Impact of Pd and Pt Complexes on Basal‐Like Triple‐Negative Breast Cancer

ChemMedChem, Volume 21, Issue 9, 14 May 2026.
The anticancer activity of the complexes Pd3Spd2, Pt3Spd2, Pt2Put2(NH3)4 and Pd2Put2 against human TNBC, non‐TNBC and healthy breast cells was evaluated. The metabolic impact of the most promising metal complexes—Pd3Spd2 and Pt2Put2(NH3)4—was further assessed using vibrational microspectroscopies, providing detailed insights into the drug‐induced ...
Clara B. Martins, Maria P. M. Marques, Luís A. E. Batista de Carvalho, Ana L. M. Batista de Carvalho   +3 more
wiley   +1 more source

Microbial metabolites short chain fatty acids, tight junction, gap junction, and reproduction: a review. [PDF]

Front Cell Dev Biol
Fu L, Wang M, Li D, Ma S, Zhang F, Zheng L.   +5 more
europepmc   +1 more source

Common Signatures of Altered Gene Regulation and Invasiveness of Different Breast Cancer Cell Lines after Matrix Interface Crossing

Advanced Healthcare Materials, Volume 15, Issue 18, 15 May 2026.
Interface transmigration reprograms triple‐negative breast cancer cells, triggering a shared switch toward more aggressive and invasive phenotypes. Using a collagen I interface model, this study identifies shared transcriptional changes involving proliferation, chromatin remodeling, and DNA repair pathways.
Cornelia Clemens, Hannah Trampert, Nataliia Kotsiuba, Tilo Pompe   +3 more
wiley   +1 more source

Ion permeability profiles of renal paracellular channel-forming claudins. [PDF]

Acta Physiol (Oxf)
Pouyiourou I, Fromm A, Piontek J, Rosenthal R, Furuse M, Günzel D.   +5 more
europepmc   +1 more source

A Physiological Microfluidic Blood–Brain‐Barrier Model for In Vitro Study of Nanoparticle Trafficking and Accumulation

Advanced Healthcare Materials, Volume 15, Issue 19, 22 May 2026.
A human microfluidic blood‐brain barrier (mBBB) model enables spatially resolved comparison of nanoparticle trafficking. Extracellular vesicles (EVs), liposomes, and nanoplastics exhibit distinct transport and disruption behaviors, revealing that membrane composition and uptake pathways govern BBB interaction.
Bryan B. Nguyen, Neona M. Lowe, Sophia Kellogg, Kuan‐Wei Huang, Hannah O'Toole, Elizabeth J. Hale, Venktesh S. Shirure, Bhupinder S. Shergill, Steven C. George, Randy P. Carney   +9 more
wiley   +1 more source

The research trends and hotspots of claudins in the field of cancer. [PDF]

Cell Adh Migr
Jing W, Long L, Zhang X, Li X, Huang H.
europepmc   +1 more source

Multicohort Validation of Gut Microbiome Signatures for Cholangiocarcinoma Diagnosis and Functional Characterization of Bifidobacterium Pseudocatenulatum

Advanced Science, Volume 13, Issue 27, 13 May 2026.
This study analyzes gut bacteria in cholangiocarcinoma patients, revealing distinct microbial signatures that enable accurate disease detection. Species‐based diagnostic models achieved over 98% accuracy in identifying cholangiocarcinoma and distinguished it from other liver diseases. The research demonstrates that specific beneficial bacteria suppress
Benchen Rao, Jianwen Jiang, Ruiqing Zhang, Dongya Zhang, Chenchen Zhang, Ang Li, Haifeng Lu, Hua Zhang, Lin Zhou, Wenzhi Guo, Peihao Wen, Jianfeng Xue, Jie Pan, Tuerganaili Aji, Zhou Lan, Xianzhi Jiang, Shusen Zheng, Zujiang Yu, Zhigang Ren   +18 more
wiley   +1 more source

Proinflammatory cytokines modify Ca²⁺ signaling and induce an apoptotic lipidome in murine small intestinal organoids. [PDF]

Front Physiol
Pauer SM, Schindler A, Ghezellou P, Spengler B, Diener M, Ballout J.   +5 more
europepmc   +1 more source

Targeted H2S Delivery System Attenuates Blood‐Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway

Advanced Science, Volume 13, Issue 28, 18 May 2026.
The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen, Xinkai Pu, Ruiyang Li, Yuezhou Wu, Qirong Zhou, Jian Wang, Yuxuan Qian, Fengjie Lu, Jian‐Yuan Zhao, Zhida Su, Jiacan Su, Xiaofeng Lian   +11 more
wiley   +1 more source

Familial hypomagnesemia with hypercalciuria and nephrocalcinosis caused by CLDN16/CLDN19 mutations in four Chinese families. [PDF]

Sci Rep
Wang C, Ding J, Yang H, Huang L, Wang X.
europepmc   +1 more source