Results 31 to 40 of about 24,575,655 (169)

Podoplanin and CLEC-2 levels in patients with COVID-19. [PDF]

Res Pract Thromb Haemost, 2023
Podoplanin (PDPN gene) and CLEC-2 are involved in inflammatory hemostasis and have also been related with the pathogenesis of thrombosis. Emerging evidence also suggest that podoplanin can exert protective effects in sepsis and in acute lung injury.
Borba-Junior IT, Lima F, Vitoria Rodrigues Oliveira DS, Peachazepi Moraes CR, Annichino-Bizzacchi JM, Bombassaro B, Palma AC, Maranhao Costa FT, Moretti ML, Mansour E, Velloso LA, Orsi FA, De Paula EV.   +12 more
europepmc   +3 more sources

GPVI and CLEC-2

, 2013
The glycoprotein VI (GPVI)-FcR gamma-chain complex initiates powerful activation of platelets by the subendothelial matrix proteins collagen and laminin, which are exposed following vessel damage.
Alice Y. Pollitt, Craig E. Hughes, Steve P. Watson   +2 more
openaire   +2 more sources

Characterisation of platelet receptor CLEC-2 in thrombosis and inflammation [PDF]

, 2022
Platelets have an established role in thrombosis and haemostasis. C-type lectin-like receptor 2 (CLEC-2) is highly expressed on platelets and a subpopulation of myeloid cells, and is critical in lymphatic development.
Bourne, Joshua Henry
core   +6 more sources

CLEC-2 and CD177 have a profound effect on the CAF phosphoproteome.

, 2021
(A) Density plots depicting the changes observed in phosphorylated residues (x-axis) versus total protein abundance changes (y-axis), for the 70% protein overlapping proteins between both assays, in all four conditions.
Victoria C. Pham (7388111), Lino C. Gonzalez (11812916), Jillian L. Astarita (11812907), Shilpa Keerthivasan (11812910), Erik Verschueren (753511), Jennie R. Lill (212568), Andrew A. Pierce (4413523), Shannon J. Turley (11812922), Sean M. Peterson (11812913), Nadia Martinez-Martin (11812919), Yasin Şenbabaoğlu (2543956), Bushra Husain (1430635), Sarah Gierke (6560351), Cecile Chalouni (1593517)   +13 more
core   +2 more sources

The Association Between Plasma C-Type Lectin Like Receptors 2 (CLEC-2) and STEMI and its Correlation With Clinicolaboratory Data

Egyptian Journal of Critical Care Medicine, 2023
Objectives To assess the association between plasma C-type lectin-like receptor 2 (CLEC-2) and ST elevation myocardial infarction (STEMI) and its correlation with clinicolaboratory data.
Salwa Hassan Ahmed, Ahmed Abd ElMoez ElSayed, Fatma Abdel Wahab Abdel Maksoud, Lamees Mohamed Fathi, Soliman Belal Soliman   +4 more
doaj   +1 more source

AVALIAÇÃO DA EXPRESSÃO DE PODOPLANINA E CLEC-2 NA DOENÇA FALCIFORME

Hematology, Transfusion and Cell Therapy, 2023
A hipercoagulabilidade é uma característica importante da doença falciforme (DF), e sua fisiopatologia está relacionada à ativação concomitante da hemostasia e da imunidade inata, em um processo conhecido como imunotrombose.
IT Borb-Junior, MS Barbosa, I Santos, BD Benites, FF Costa, EV Paula   +5 more
doaj   +1 more source

Association of C-type lectin-like receptor 2 and galectin-1 with portal vein system thrombosis in HBV-related liver cirrhosis

Frontiers in Medicine, 2023
Background and aimsHepatitis B virus (HBV) infection is the most common cause of liver cirrhosis. Portal venous system thrombosis (PVST) is a major complication of liver cirrhosis.
Yiyan Zhang, Yiyan Zhang, Xintong Zhang, Xiangbo Xu, Xiangbo Xu, Xiaozhong Guo, Shixue Xu, Shixue Xu, Shaoze Ma, Shaoze Ma, Jihong Chen, Jihong Chen, Xingshun Qi   +12 more
doaj   +1 more source

Association between c-type lectin-like receptor 2 and microsatellite instability in colorectal cancer: a cross-sectional study

BMC Cancer, 2022
Background As a transmembrane protein, C-type lectin-like receptor 2 (CLEC-2) is mainly expressed on platelets and released into plasma after platelet activation. Activated platelets participate in the regulation of innate immune cells.
Xin Zhang, Jia-rui Yuan, Xin Wang, Shuang Fu, Rui-tao Wang, Guang-yu Wang   +5 more
doaj   +1 more source

Quantitative single molecule analysis of podoplanin clustering in fibroblastic reticular cells uncovers CD44 function

Open Biology, 2023
Upon initial immune challenge, dendritic cells (DCs) migrate to lymph nodes and interact with fibroblastic reticular cells (FRCs) via C-type lectin-like receptor 2 (CLEC-2).
Shu En Lim, Megan D. Joseph, Charlotte M. de Winde, Sophie E. Acton, Sabrina Simoncelli   +4 more
doaj   +1 more source

Platelet CLEC-2: a molecule with 2 faces.

Blood, 2017
In this issue of Blood , Haining et al reveal an unexpected role for platelet C-type lectin-like receptor-2 (CLEC-2) in thrombosis, which is independent of its hemi-immunoreceptor tyrosine-based activation motif (hemITAM) signaling ...
Xia L.
europepmc   +4 more sources