Results 151 to 160 of about 171,782 (185)

Mode of action guided metagenomic natural product discovery reveals convergent evolution of a ClpP-targeting motif. [PDF]

open access: yesNat Commun
Kan J   +9 more
europepmc   +1 more source

Clp Chaperone–Proteases: Structure and Function

open access: yesResearch in Microbiology, 2009
Clp proteases are the most widespread energy-dependent proteases in bacteria. Their two-component architecture of protease core and ATPase rings results in an inventory of several Clp protease complexes that often coexist. Here, we present insights into Clp protease function, from their assembly to substrate recruitment and processing, and how this is ...
Eilika Weber-Ban   +2 more
exaly   +8 more sources

The Clp Protease System; A Central Component of the Chloroplast Protease Network

open access: yesBiochimica Et Biophysica Acta - Bioenergetics, 2011
Intra-plastid proteases play crucial and diverse roles in the development and maintenance of non-photosynthetic plastids and chloroplasts. Formation and maintenance of a functional thylakoid electron transport chain requires various protease activities, operating in parallel, as well as in series. This review first provides a short, referenced overview
Jitae Kim   +2 more
exaly   +3 more sources

Clp Protease and OR Directly Control the Proteostasis of Phytoene Synthase, the Crucial Enzyme for Carotenoid Biosynthesis in Arabidopsis [PDF]

open access: yesMolecular Plant, 2018
Ajuts: This work was supported by Agriculture and Food Research Initiative competitive award no. 2016-67013-24612 from the USDA National Institute of Food and Agriculture and by the HarvestPlus research consortium (2014H6320.FRE)Phytoene synthase (PSY ...
Manuel Rodriguez-Concepcion   +2 more
exaly   +2 more sources
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Tagging Proteins for the Clp Protease

Nature Reviews Microbiology, 2016
Katharine Wrighton
exaly   +2 more sources

Clp-Targeting BacPROTACs Impair Mycobacterial Proteostasis and Survival [PDF]

open access: yesCell, 2023
The ClpC1:ClpP1P2 protease is a core component of the proteostasis system in mycobacteria. To improve the efficacy of antitubercular agents targeting the Clp protease, we characterized the mechanism of the antibiotics cyclomarin A and ecumicin ...
Anton Meinhart, Tim Clausen
exaly   +3 more sources

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