SpxA1 and SpxA2 act coordinately to fine-tune stress responses and virulence in Streptococcus pyogenes [PDF]
, 2017 SpxA is a unique transcriptional regulator highly conserved among members of the phylum Firmicutes that binds RNA polymerase and can act as an antiactivator. Why some Firmicutes members have two highly similar SpxA paralogs is not understood.
Gary C. Port +4 more
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Mcx1p, a ClpX homologue in mitochondria of Saccharomyces cerevisiae [PDF]
FEBS Letters, 1998 Members of the Hsp100/Clp‐family of molecular chaperones form regulatory subunits of ATP‐dependent Clp proteases and fulfill crucial roles for cellular thermotolerance. We have identified a Clp‐like protein in Saccharomyces cerevisiae, Mcx1p, which shares approximately 30% sequence identity with ClpX‐proteins in bacteria, plants and nematodes.
van Dyck, L. +3 more
openaire +3 more sources
PLoS ONE, 2010 The Clp ATPases (Hsp100) constitute a family of closely related proteins that have protein reactivating and remodelling activities typical of molecular chaperones.
Lotte Jelsbak +6 more
doaj +1 more source
The effects of variation in snow properties on passive microwave snow mass estimation [PDF]
, 2012 Estimating snow mass at continental scales is difficult, but important for understanding land-atmosphere interactions, biogeochemical cycles and the hydrology of the Northern latitudes.
Davenport, Ian +2 more
core +1 more source
Distribution of the clpX gene in Brachyspira species and reactivity of recombinant Brachyspira pilosicoli ClpX with sera from mice and humans [PDF]
Journal of Medical Microbiology, 2007 Previously, aclpXgene encoding a predicted 67 kDa membrane-associated ATPase subunit of the Clp protease (ClpX) was identified in a porcine strain (95/1000) of the intestinal spirochaeteBrachyspira pilosicoli.In the current study, the distribution of this largeclpXgene was investigated in a collection of strains representing all sevenBrachyspiraspp ...
Movahedi, A., Hampson, D.J.
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Frontiers in Molecular Biosciences, 2017 ClpX is a member of the Clp/Hsp100 family of ATP-dependent chaperones and partners with ClpP, a compartmentalized protease, to degrade protein substrates bearing specific recognition signals.
Christopher J. LaBreck +4 more
doaj +1 more source
NASA Cold Land Processes Experiment (CLPX 2002/03): ground-based and near-surface meteorological observations [PDF]
, 2008 A short-term meteorological database has been developed for the Cold Land Processes Experiment (CLPX). This database includes meteorological observations from stations designed and deployed exclusively for CLPXas well as observations available from other
Cline, Don +5 more
core +1 more source
ClpX, a Stochastic Protein Unfolding and Translocation Machine [PDF]
Biophysical Journal, 2014 During protein degradation by ClpXP, AAA+ ClpX hexamers grip protein substrates using GYVG pore loops and harness the energy of ATP binding and hydrolysis to the drive conformational changes necessary for the mechanical denaturation and translocation of the substrate into the ClpP chamber.
Sauer, Robert T. +11 more
openaire +1 more source
The phenazine pyocyanin is a terminal signalling factor in the quorum sensing network of Pseudomonas aeruginosa [PDF]
, 2006 Certain members of the fluorescent pseudomonads produce and secrete phenazines. These heterocyclic, redox-active compounds are toxic to competing organisms, and the cause of these antibiotic effects has been the focus of intense research efforts.
Dietrich, Lars E. P. +4 more
core +1 more source
TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switching. [PDF]
, 2015 The AAA+ family ATPase TRIP13 is a key regulator of meiotic recombination and the spindle assembly checkpoint, acting on signaling proteins of the conserved HORMA domain family.
Corbett, Kevin D +5 more
core +2 more sources