Results 41 to 50 of about 4,851 (193)
Degradation of a Caulobacter Soluble Cytoplasmic Chemoreceptor Is ClpX Dependent [PDF]
Journal of Bacteriology, 2002 ABSTRACT In order to determine whether ClpXP-mediated proteolysis is a common mechanism used to regulate the chemotaxis machinery during the cell cycle of Caulobacter crescentus , we have characterized a soluble cytoplasmic chemoreceptor, McpB.
Potocka, I. +4 more
openaire +3 more sources
, 2022 Protein homeostasis is tightly regulated by protein quality control systems such as chaperones and proteases. In cyanobacteria, the ClpXP proteolytic complex is regarded as a representative proteolytic system and consists of a hexameric ATPase ClpX and a
Yumeng Zhang (3115050) +6 more
core +1 more source
, 2022 Protein homeostasis is tightly regulated by protein quality control systems such as chaperones and proteases. In cyanobacteria, the ClpXP proteolytic complex is regarded as a representative proteolytic system and consists of a hexameric ATPase ClpX and a
Yumeng Zhang (3115050) +6 more
core +1 more source
Disassembly of the Mu transposase tetramer by the ClpX chaperone. [PDF]
Genes & Development, 1995 Mu transposition is promoted by an extremely stable complex containing a tetramer of the transposase (MuA) bound to the recombining DNA. Here we purify the Escherichia coli ClpX protein, a member of a family of multimeric ATPases present in prokaryotes and eukaryotes (the Clp family), on the basis of its ability to remove the transposase from the DNA ...
I, Levchenko, L, Luo, T A, Baker
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ClpX, a Stochastic Protein Unfolding and Translocation Machine [PDF]
Biophysical Journal, 2014 During protein degradation by ClpXP, AAA+ ClpX hexamers grip protein substrates using GYVG pore loops and harness the energy of ATP binding and hydrolysis to the drive conformational changes necessary for the mechanical denaturation and translocation of the substrate into the ClpP chamber.
Sauer, Robert T. +11 more
openaire +1 more source
, 2022 Protein homeostasis is tightly regulated by protein quality control systems such as chaperones and proteases. In cyanobacteria, the ClpXP proteolytic complex is regarded as a representative proteolytic system and consists of a hexameric ATPase ClpX and a
Yumeng Zhang (3115050) +6 more
core +1 more source
Deciphering the Roles of Multicomponent Recognition Signals by the AAA + Unfoldase ClpX [PDF]
Journal of Molecular Biology, 2015 ATP-dependent protein remodeling and unfolding enzymes are key participants in protein metabolism in all cells. How these often-destructive enzymes specifically recognize target protein complexes is poorly understood. Here, we use the well-studied AAA+ unfoldase-substrate pair, Escherichia coli ClpX and MuA transposase, to address how these powerful ...
Montaño, Sherwin P. +4 more
openaire +4 more sources
, 2022 Protein homeostasis is tightly regulated by protein quality control systems such as chaperones and proteases. In cyanobacteria, the ClpXP proteolytic complex is regarded as a representative proteolytic system and consists of a hexameric ATPase ClpX and a
Yumeng Zhang (3115050) +6 more
core +1 more source
The EMBO Journal, 1995 All major classes of protein chaperones, including DnaK (the Hsp70 eukaryotic equivalent) and GroEL (the Hsp60 eukaryotic equivalent) have been found in Escherichia coli. Molecular chaperones enhance the yields of correctly folded polypeptides by preventing aggregation and even by disaggregating certain protein aggregates. Previously, we identified the
Alicja Wawrzynów +7 more
openaire +3 more sources
PLoS Pathogens, 2019 β-lactam antibiotics interfere with cross-linking of the bacterial cell wall, but the killing mechanism of this important class of antibiotics is not fully understood.
Camilla Jensen +11 more
doaj +1 more source