Results 71 to 80 of about 7,556 (201)
Microtubule-severing enzymes: From cellular functions to molecular mechanism. [PDF]
, 2018 Microtubule-severing enzymes generate internal breaks in microtubules. They are conserved in eukaryotes from ciliates to mammals, and their function is important in diverse cellular processes ranging from cilia biogenesis to cell division, phototropism ...
Ahmad +130 more
core +2 more sources
Disassembly of the Mu transposase tetramer by the ClpX chaperone. [PDF]
Genes & Development, 1995 Mu transposition is promoted by an extremely stable complex containing a tetramer of the transposase (MuA) bound to the recombining DNA. Here we purify the Escherichia coli ClpX protein, a member of a family of multimeric ATPases present in prokaryotes and eukaryotes (the Clp family), on the basis of its ability to remove the transposase from the DNA ...
I, Levchenko, L, Luo, T A, Baker
openaire +2 more sources
VIEW, EarlyView.Pancreatic cancer (PaCa) has a poor prognosis, with low resection rates and high relapse rates, highlighting the urgent need for novel diagnostic biomarkers. Here, we performed whole‐transcriptome sequencing of plasma‐derived exosomes from PaCa patients and identified several differentially expressed circular RNAs (circRNAs).
Xiaomeng He +10 more
wiley +1 more source
Cell Reports, 2015 In the axial channels of ClpX and related hexameric AAA+ protein-remodeling rings, the pore-1 loops are thought to play important roles in engaging, mechanically unfolding, and translocating protein substrates. How these loops perform these functions and
Ohad Iosefson +3 more
doaj +1 more source
Identifying Subcellular Structure Components in Escherichia Coli by Crosslinking and SEC‐MS
PROTEOMICS, Volume 26, Issue 5, Page 27-36, May 2026.ABSTRACT Cells are comprised of a broad spectrum of structures that compartmentalize biochemical and signaling mechanisms. These structures can be comprised of many biomolecules, but especially lipids, proteins, and nucleic acids. Techniques are limited to quantify or discover new subcellular structures.
Rachel A. Victor +3 more
wiley +1 more source
Microorganisms, 2023 Antibiotic resistance is a significant and pressing issue in the medical field, as numerous strains of infectious bacteria have become resistant to commonly prescribed antibiotics.
Darya V. Poshvina +2 more
doaj +1 more source
Multiscale assimilation of Advanced Microwave Scanning Radiometer-EOS snow water equivalent and Moderate Resolution Imaging Spectroradiometer snow cover fraction observations in northern Colorado [PDF]
, 2012 Eight years (2002–2010) of Advanced Microwave Scanning Radiometer–EOS (AMSR-E) snow water equivalent (SWE) retrievals and Moderate Resolution Imaging Spectroradiometer (MODIS) snow cover fraction (SCF) observations are assimilated separately or jointly ...
Arsenault, Kristi R +6 more
core +2 more sources
Nature Communications, 2023 Bacteriophages (phages) are the most abundant biological entities on Earth, exerting a significant influence on the dissemination of bacterial virulence, pathogenicity, and antimicrobial resistance.
Mohammed A. Thabet +2 more
doaj +1 more source
Advanced Science, Volume 13, Issue 20, 9 April 2026.ARTP mutagenesis yielded Saccharopolyspora spinosa mutant D184 with improved extracellular nitrogen utilization. An integrated workflow of protease genetic manipulation, multi‐omics, and rational synergy design pinpointed a pepP‐clpP‐htpX synergistic triangular combination.
Duo Jin +9 more
wiley +1 more source
Cohesin cleavage by separase is enhanced by a substrate motif distinct from the cleavage site. [PDF]
, 2019 Chromosome segregation begins when the cysteine protease, separase, cleaves the Scc1 subunit of cohesin at the metaphase-to-anaphase transition.
Asfaha, Jonathan B +6 more
core +1 more source