Results 71 to 80 of about 3,073 (171)

Gut Microbiota Composition in Adolescents From Mexico City, Associations With Nutritional and Socioeconomic Factors: Results From a Pilot Study

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 2, 29 January 2026.
This study analyzed the gut microbiota composition of 95 adolescents and its relationship with body mass index, dietary habits, and socioeconomic status using 16S rRNA sequencing (V3‐V4). The dominant phyla in the gut microbiome were Bacteroidetes, Firmicutes, and Proteobacteria, while enterotype‐like patterns were mainly driven by Bacteroides and ...
Armando Navarro   +11 more
wiley   +1 more source

Proinflammatory Mechanism of N-Glycolylneuraminic Acid in Mice through Regulating the Gut Microbiota [PDF]

open access: yesShipin Kexue
In this study, the effect of 18 weeks of dietary supplementation of porcine submaxillary gland mucin (PSM) as an abundant source of N-hydroxyacetylneuraminic acid (Neu5Gc) on the expression of proteins involved in the nuclear factor kappa-B (NF-κB ...
HE Leli, LIU Chuxin, XIAO Yi, SHEN Qingwu, WU Yanyang
doaj   +1 more source

Human-like Cmah inactivation in mice increases running endurance and decreases muscle fatigability: implications for human evolution [PDF]

open access: yesProceedings of the Royal Society B: Biological Sciences, 2018
Compared to other primates, humans are exceptional long-distance runners, a feature that emerged in genusHomoapproximately 2 Ma and is classically attributed to anatomical and physiological adaptations such as an enlarged gluteus maximus and improved heat dissipation. However, no underlying genetic changes have currently been defined.
Jonathan Okerblom   +5 more
openaire   +4 more sources

Microglia Display Altered Spatial Morphology and Proteome After Stroke

open access: yesPROTEOMICS, Volume 25, Issue 23, Page 59-76, December 2025.
ABSTRACT Microglia are abundantly distributed throughout the central nervous system (CNS) to play critical roles in neural development and homeostasis, and act as immune sentinels to constantly monitor their surrounding neural environment. Given their high reactivity to brain insults, we hypothesised that the cerebral microenvironment altered by ...
Brooke J. Wanrooy   +10 more
wiley   +1 more source

The use of transgenic animals for xenotransplantation: An update

open access: yesAnimal Models and Experimental Medicine, Volume 8, Issue 11, Page 2041-2052, November 2025.
One way to produce genetically modified pigs is to use somatic cell nuclear transfer (SCNT). This procedure involves removing the metaphase plate from a mature oocyte using micromanipulation and then transferring the modified nucleus from the donor somatic cell to the oocyte.
Julia Motławska   +3 more
wiley   +1 more source

Exogenous incorporation of neugc-rich mucin augments n-glycolyl sialic acid content and promotes malignant phenotype in mouse tumor cell lines

open access: yesJournal of Experimental & Clinical Cancer Research, 2009
Background Carbohydrates embedded in the plasma membrane are one of the main actors involved in the communication of cells with the microenvironment. Neuraminic sialic acids are glycocalyx sugars that play important roles in the modulation of malignant ...
Alonso Daniel F   +3 more
doaj   +1 more source

Revolutionizing Heart Valve Therapy: A Translational Framework for Combining Decellularized Scaffolds With Genetic Modification

open access: yesJournal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 113, Issue 11, November 2025.
ABSTRACT Valvular heart disease (VHD) represents a significant global health challenge, affecting over 2.5% of the population and disproportionately impacting older adults due to age‐related degenerative processes. Current treatment options—mechanical and bioprosthetic valves—both present substantial limitations that impact patient quality of life and ...
Nikolaos P. Tzavellas   +8 more
wiley   +1 more source

CMAH genotyping survey for blood types A, B and C (AB) in purpose‐bred cats [PDF]

open access: yesAnimal Genetics, 2019
SummaryIn domestic cats, the AB blood group system consists of the three types A, B and C (also called AB). Mismatches can cause acute hemolytic transfusion reactions and hemolysis of the newborn (neonatal isoerythrolysis, NI). As blood types B and C are inherited recessively to A, breeders need to know the genotype to predict blood types in offspring ...
A. Kehl, E. Mueller, U. Giger
openaire   +2 more sources

Xenotransplantation: past, present, and future [PDF]

open access: yes, 2017
PURPOSE OF REVIEW: To review the progress in the field of xenotransplantation with special attention to most recent encouraging findings which will eventually bring xenotransplantation to the clinic in the near future.
Cooper, David K.C.   +2 more
core   +1 more source

Porcine Corneal Tissue and Xenozoonotic Risks: A Review of the Current Evidence

open access: yesXenotransplantation, Volume 32, Issue 6, November/December 2025.
ABSTRACT Corneal opacities affect millions worldwide, with corneal transplantation as the primary treatment. However, donor shortages remain a challenge, leaving thousands waiting for transplants. Xenotransplantation using porcine corneas has emerged as a promising alternative due to anatomical and physiological similarities with human corneas ...
Rodrigo Moreira   +13 more
wiley   +1 more source

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