Results 51 to 60 of about 2,006 (151)
Coastal development can alter the salinity fluctuations experienced by tidal creek systems. Understanding how resident organisms, such as the Gulf killifish, respond to these changes is critical, as development along the coastline is projected to triple in the coming decades.
Antrelle D. Clark +3 more
wiley +1 more source
Background The use of immunodeficient mice transplanted with human hematopoietic stem cells is an accepted approach to study human-specific infectious diseases such as HIV-1 and to investigate multiple aspects of human immune system development. However,
Raghubendra Singh Dagur +11 more
doaj +1 more source
A simple method for assessment of human anti-Neu5Gc antibodies applied to Kawasaki disease. [PDF]
N-glycolylneuraminic acid (Neu5Gc) is an immunogenic sugar of dietary origin that metabolically incorporates into diverse native glycoconjugates in humans.
Vered Padler-Karavani +5 more
doaj +1 more source
N-glycolylneuraminic acid as a carbohydrate cancer biomarker
One of the forms of aberrant glycosylation in human tumors is the expression of N-glycolylneuraminic acid (Neu5Gc). The only known enzyme to biosynthesize Neu5Gc in mammals, cytidine-5′-monophosphate-N-acetylneuraminic acid (CMAH), appears to be ...
Jing Wang +3 more
doaj +1 more source
The Potential Role of Expression of HLA‐E and HLA‐G in Organ Xenotransplantation
ABSTRACT Xenotransplantation offers a promising solution to the shortage of human organs for transplantation but requires overcoming numerous immune responses—particularly those mediated by the innate immune system through natural killer (NK) cells and macrophages.
Jeffrey K. Sumbo +4 more
wiley +1 more source
Proinflammatory Mechanism of N-Glycolylneuraminic Acid in Mice through Regulating the Gut Microbiota [PDF]
In this study, the effect of 18 weeks of dietary supplementation of porcine submaxillary gland mucin (PSM) as an abundant source of N-hydroxyacetylneuraminic acid (Neu5Gc) on the expression of proteins involved in the nuclear factor kappa-B (NF-κB ...
HE Leli, LIU Chuxin, XIAO Yi, SHEN Qingwu, WU Yanyang
doaj +1 more source
ABSTRACT Xenotransplantation has entered a phase of accelerated clinical translation, necessitating renewed international consensus on governance, ethics, safety, and regulatory oversight. In September 2025, the International Xenotransplantation Association (IXA), in partnership with The Transplantation Society (TTS) and with engagement from the World ...
Wayne J. Hawthorne +25 more
wiley +1 more source
Xenotransplantation Literature Update: January–June 2026
ABSTRACT In the first half of 2026, xenotransplantation advanced through refinement rather than dramatic new clinical milestones. Clinical studies described graft physiology, immune infiltration, complement activation, coagulation incompatibility, and early function in living recipients, decedent models, and clinical islet xenotransplantation ...
Kasra Shirini +3 more
wiley +1 more source
Background Pig erythrocytes are potentially useful to solve the worldwide shortage of human blood for transfusion. Domestic pig erythrocytes, however, express antigens that are bound by human preformed antibodies.
Tector, A. Joseph +6 more
core +1 more source
Additional file 1 Multiple alignment of the deduced amino acid sequences of CMAH in various species. Dot(.): same sequence for dog CMAH, dash (−): missing sequence for dog CMAH, *: position of amino acid residue at 185 that corresponded to dog CMAH (p ...
Yumiko Uno (2342851) +3 more
core +1 more source

