Results 61 to 70 of about 2,006 (151)

Minimal Consequences of CMAH and DBA/2J Background on a FKRP Deficient Model

, 2021
International audienceBackground: Muscular dystrophies (MD) are a large group of genetic diseases characterized by a progressive loss of muscle. The Latent TGFβ Binding Protein 4 (LTBP4) and the Cytidine Monophosphate-sialic Acid Hydroxylase (CMAH ...
Gicquel, Evelyne, Bellec, Jessica, Richard, Isabelle, Lostal, William, Vaubourg, Camille   +4 more
core   +1 more source

Exogenous incorporation of neugc-rich mucin augments n-glycolyl sialic acid content and promotes malignant phenotype in mouse tumor cell lines

Journal of Experimental & Clinical Cancer Research, 2009
Background Carbohydrates embedded in the plasma membrane are one of the main actors involved in the communication of cells with the microenvironment. Neuraminic sialic acids are glycocalyx sugars that play important roles in the modulation of malignant ...
Alonso Daniel F, Gomez Daniel E, Otero Laura L, Gabri Mariano R   +3 more
doaj   +1 more source

Loss of CMAH during Human Evolution Primed the Monocyte–Macrophage Lineage toward a More Inflammatory and Phagocytic State [PDF]

, 2017
Humans and chimpanzees are more sensitive to endotoxin than are mice or monkeys, but any underlying differences in inflammatory physiology have not been fully described or understood.
Martin, Paul T, Schwarz, Flavio, Varki, Ajit, Ali, Syed Raza, Glass, Christopher K, Victor Nizet, Josh Olson, Syed Raza Ali, Christopher K. Glass, William Fletes, Flavio Schwarz, Ajit Varki, Jonathan J. Okerblom, Paul T. Martin, Okerblom, Jonathan J, Olson, Josh, Fletes, William, Nizet, Victor   +17 more
core   +1 more source

Current Status of Kidney Xenotransplantation in Basic Research

Organ Medicine, Volume 3, Issue 2, Page 87-101, June 2026.
Kidney xenotransplantation is a potential solution to the organ shortage for end‐stage kidney disease. This review systematically elaborates on the application advances of donor pig gene editing technologies, the molecular mechanisms and regulatory strategies of xenogeneic immune rejection, and the optimization approaches of immune compatibility ...
Yu Luo, Bingzhuo Liu, Weijie Lai
wiley   +1 more source

Schematic representation of biological networks was constructed by CMAH function.

, 2014
A. Validation of microarray gene expression by RT-qPCR. Gene expression levels of selected genes were determined by RT-qPCR using WT and Cmah-dKO derived lung, kidney, and heart tissues.
Byung-Soo Chang (630761), Deug-Nam Kwon (630760), Jin-Hoi Kim (577191)   +2 more
core   +1 more source

A Novel Variant in CMAH Is Associated with Blood Type AB in Ragdoll Cats. [PDF]

PLoS ONE, 2016
The enzyme cytidine monophospho-N-acetylneuraminic acid hydroxylase is associated with the production of sialic acids on cat red blood cells. The cat has one major blood group with three serotypes; the most common blood type A being dominant to type B. A
Barbara Gandolfi, Robert A Grahn, Nicholas A Gustafson, Daniela Proverbio, Eva Spada, Badri Adhikari, Janling Cheng, Gordon Andrews, Leslie A Lyons, Chris R Helps   +9 more
doaj   +1 more source

Biofilm Formation and Spore‐Mediated Persistence of Clostridium perfringens in Meat and Poultry Processing Environments and Their Implications for Control Strategies

Journal of Food Science, Volume 91, Issue 6, June 2026.
ABSTRACT Clostridium perfringens (C. perfringens) biofilms pose a persistent challenge in meat and poultry processing environments due to their structural resilience, spore‐mediated survival and toxin‐associated virulence. These biofilms readily develop on food‐contact surfaces under typical processing conditions including organic residue accumulation,
Md Anamul Hasan Chowdhury, Chowdhury Sanat Anjum Reem, Md. Ashrafudoulla, Hae Jung Yoon, Sang‐Do Ha   +4 more
wiley   +1 more source

Preclinical Evaluation of Long-Acting Emtricitabine Semi-Solid Prodrug Nanoparticle Formulations

Pharmaceutics, 2023
Long-acting injectable (LAI) formulations promise to deliver patient benefits by overcoming issues associated with non-adherence. A preclinical assessment of semi-solid prodrug nanoparticle (SSPN) LAI formulations of emtricitabine (FTC) is reported here.
Paul Curley, James J. Hobson, Neill J. Liptrott, Edward Makarov, Amer Al-khouja, Lee Tatham, Christopher A. W. David, Helen Box, Megan Neary, Joanne Sharp, Henry Pertinez, David Meyers, Charles Flexner, Caren L. Freel Meyers, Larisa Poluektova, Steve Rannard, Andrew Owen   +16 more
doaj   +1 more source

Correction: A Novel Variant in CMAH Is Associated with Blood Type AB in Ragdoll Cats. [PDF]

PLoS ONE, 2018
[This corrects the article DOI: 10.1371/journal.pone.0154973.].
Barbara Gandolfi, Robert A Grahn, Nicholas A Gustafson, Daniela Proverbio, Eva Spada, Badri Adhikari, Janling Cheng, Gordon Andrews, Leslie A Lyons, Chris R Helps   +9 more
doaj   +1 more source

Synergistic effect of organic and inorganic fertilizers on Aloe vera: Enhancing leaf biomass, nutrient uptake, medicinal properties, and soil fertility

Agrosystems, Geosciences &Environment, Volume 9, Issue 1, March 2026.
Abstract Aloe vera (Aloe vera L.) has been utilized for various therapeutic and cosmetic purposes; however, its agronomic management in Bangladesh remains underexplored. Therefore, a field trial was performed in Mymensingh, Bangladesh, to evaluate the combined effects of organic and inorganic fertilizers (IFs) on growth, nutrient composition, medicinal
Niloy Majumder, Md. Akhter Hossain Chowdhury, Rakibul Hasan Md. Rabbi, Sanjida Yeasmin Etu, Biplob Kumar Saha   +4 more
wiley   +1 more source