Results 71 to 80 of about 84,756 (126)

Poly(A) tail regulation in stem cells and early development. [PDF]

Cell Regen
Miao X, Hu G.
europepmc   +1 more source

Auxin-induced depletion of human CCR4-NOT subunits reveals opposing functions of CNOT1 and CNOT4 in mRNA metabolism. [PDF]

J Biol Chem
Kulkarni S, Smith C, Akinniyi OT, Giardine BM, Keller CA, Arnaoutov A, Reese JC.   +6 more
europepmc   +1 more source

The CCR4-NOT complex: a multifaceted sensor of molecular signals instructing eukaryotic mRNA translation and stability. [PDF]

Nucleic Acids Res
Caulier G, Siblini J, Sène L, Mauxion F, Séraphin B.   +4 more
europepmc   +1 more source

The anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7)/Caf1b (CNOT8) deadenylase enzymes [PDF]

The human BTG/TOB protein family comprises six members (BTG1, BTG2/PC3/Tis21, BTG3/Ana, BTG4/PC3B, TOB1/Tob, and TOB2) that display anti-proliferative activity in a number of cell types. They are characterised by a conserved N-terminal BTG domain that mediates interactions with the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylases.
openaire  

The CCR4-NOT deadenylase complex mediates tubulin autoregulation <i>via</i> specific adapters CNOT10 and CNOT11. [PDF]

MicroPubl Biol
Sarbanes SL, Hogg JR, Roll-Mecak A.
europepmc   +1 more source

Author Correction: AAV-based delivery of RNAi targeting ataxin-2 improves survival and pathology in TDP-43 mice. [PDF]

Nat Commun
Amado DA, Robbins AB, Whiteman KR, Smith AR, Chillon G, Chen Y, Fuller JA, Patty NA, Izda A, Cheng C, Nelson S, Dichter AI, Mazzoni EO, Monteys AM, Davidson BL.   +14 more
europepmc   +1 more source

Investigation of the PABPC1-BTG2 interaction and its effects on mRNA deadenylation by CNOT7(CAF1)

Polyadenylation is the process of the addition of a poly(A) tail to the 3ʹ end of mRNA. The binding of human poly(A) binding protein to the poly(A) tail can either initiate or repress translation or regulate mRNA degradation. Cytoplasmic mRNA degradation in eukaryotes involves shortening of mRNA poly(A) tail by poly(A)-selective ribonuclease ...
openaire  

RNF219 RING Finger Domain Mutants Drive Phase Separation to Encapsulate CCR4-NOT and Promote Cell Proliferation. [PDF]

Cell Prolif
Chen C, Guo C, Fang K, Lin C, Luo Z.
europepmc   +1 more source

Correction: Suppression of local type I interferon by gut microbiota-derived butyrate impairs antitumor effects of ionizing radiation. [PDF]

J Exp Med
Yang K, Hou Y, Zhang Y, Liang H, Sharma A, Zheng W, Wang L, Torres R, Tatebe K, Chmura SJ, Pitroda SP, Gilbert JA, Fu YX, Weichselbaum RR.   +13 more
europepmc   +1 more source

Identification of biomarkers for endometriosis based on summary-data-based Mendelian randomization and machine learning. [PDF]

Medicine (Baltimore)
Xie Z, Feng Y, He Y, Lin Y, Wang X.
europepmc   +1 more source