Results 31 to 40 of about 11,037 (206)
A 2:1 cocrystal of 6,13-dihydropentacene and pentacene [PDF]
, 2002 6,13-Dihydropentacene and pentacene cocrystallize in a ratio of 2:1, i.e. C22H16·0.5C22H14, during vapour transport of commercial pentacene in a gas flow.
Baas, Jacob, +6 more
core +5 more sources
Acta Pharmaceutica Sinica B, 2019 Pharmaceutical cocrystals are a promising technology that can be used to improve the solubility of poor aqueous compounds. The objective of this study was to systematically investigate the solubility of myricetin (MYR) cocrystals, including their kinetic
Shuzhen Ren +7 more
doaj +1 more source
Vibrational spectra of C60C8H8 and C70C8H8 in the rotor-stator and polymer phases [PDF]
, 2007 C60-C8H8 and C70-C8H8 are prototypes of rotor-stator cocrystals. We present infrared and Raman spectra of these materials and show how the rotor-stator nature is reflected in their vibrational properties.
Abe H. +28 more
core +1 more source
Urea as a Cocrystal Former—Study of 3 Urea Based Pharmaceutical Cocrystals [PDF]
Pharmaceutics, 2021 Cocrystallization is commonly used for its ability to improve the physical properties of APIs, such as solubility, bioavailability, compressibility, etc. The pharmaceutical industry is particularly interested in those cocrystals comprising a GRAS former in connection with the target API.
Fucheng Leng, Koen Robeyns, Tom Leyssens
openaire +4 more sources
Hoogsteen base pairs proximal and distal to echinomycin binding sites on DNA [PDF]
, 1987 Forms of the DNA double helix containing non-Watson-Crick base-pairing have been discovered recently based on x-ray diffraction analysis of quinoxaline antibiotic-oligonucleotide complexes.
Dervan, Peter B., Mendel, David
core +2 more sources
Pharmaceutical Cocrystal of Piroxicam: Design, Formulation and Evaluation [PDF]
Advanced Pharmaceutical Bulletin, 2017 Purpose: Cocrystallisation of drug with coformers is a promising approach to alter the solid sate properties of drug substances like solubility and dissolution.
Prabhakar Panzade +3 more
doaj +1 more source
Coordination networks incorporating halogen-bond donor sites and azobenzene groups [PDF]
, 2016 Two Zn coordination networks, [Zn(1)(Py)2]2(2-propanol)n (3) and [Zn(1)2(Bipy)2](DMF)2n (4), incorporating halogen-bond (XB) donor sites and azobenzene groups have been synthesized and fully characterized.
Fernandez-Palacio F. +6 more
core +1 more source
Uracil Derivatives for Halogen-Bonded Cocrystals [PDF]
International Journal of Molecular Sciences, 2021 Among non-covalent interactions, halogen bonding is emerging as a new powerful tool for supramolecular self-assembly. Here, along with a green and effective method, we report three new halogen-bonded cocrystals containing uracil derivatives and 1,2,4,5-tetrafluoro-3,6-diiodobenzene as X-bond donor coformer.
Mónica Benito +4 more
openaire +4 more sources
A nano-cocrystal strategy to improve the dissolution rate and oral bioavailability of baicalein
Asian Journal of Pharmaceutical Sciences, 2019 Baicalein (BE) is one of the main active flavonoids representing the variety of pharmacological effects including anticancer, anti-inflammatory and cardiovascular protective activities, but it's very low solubility, dissolution rate and poor oral ...
Jiaxin Pi +9 more
doaj +1 more source
Pharmaceutical Cocrystals: Regulatory and Strategic Aspects, Design and Development [PDF]
Advanced Pharmaceutical Bulletin, 2016 Cocrystal is a concept of the supramolecular chemistry which is gaining the extensive interest of researchers from pharmaceutical and chemical sciences and of drug regulatory agencies.
Dipak Dilip Gadade +1 more
doaj +1 more source