Results 11 to 20 of about 49,031 (262)

Distinct responses to rare codons in select Drosophila tissues

open access: yeseLife, 2022
Codon usage bias has long been appreciated to influence protein production. Yet, relatively few studies have analyzed the impacts of codon usage on tissue-specific mRNA and protein expression.
Scott R Allen   +8 more
doaj   +1 more source

Comparative analysis of codon usage patterns of FUT2 from different species

open access: yesKuwait Journal of Science, 2022
Enterotoxigenic E. coli is an important zoonotic pathogen causing diarrhea in human and newborn animals. α - (1,2) fucosyltransferase 2 (FUT2) is closely associated with the formation of pathogenic receptors of Enterotoxigenic E. coli.
Chao Xu   +3 more
doaj   +1 more source

Modal Codon Usage: Assessing the Typical Codon Usage of a Genome [PDF]

open access: yesMolecular Biology and Evolution, 2009
Most genomes are heterogeneous in codon usage, so a codon usage study should start by defining the codon usage that is typical to the genome. Although this is commonly taken to be the genomewide average, we propose that the mode-the codon usage that matches the most genes-provides a more useful approximation of the typical codon usage of a genome.
Davis, James J., Olsen, Gary J.
openaire   +2 more sources

COUSIN (COdon Usage Similarity INdex): A normalized measure of Codon Usage Preferences [PDF]

open access: yesGenome Biology and Evolution, 2019
AbstractCodon Usage Preferences (CUPrefs) describe the unequal usage of synonymous codons at the gene, genomic region or genome scale. Numerous indices have been developed to measure the CUPrefs of a sequence. We introduce a normalized index to calculate CUPrefs called COUSIN for COdon Usage Similarity INdex.
Bourret, Jérôme   +2 more
openaire   +3 more sources

Decoding the codon usage patterns in Y-domain region of hepatitis E viruses

open access: yesJournal of Genetic Engineering and Biotechnology, 2022
Background Hepatitis E virus (HEV) is a positive-sense RNA virus belonging to the family Hepeviridae. The genome of HEV is organized into three open-reading frames (ORFs): ORF1, ORF2, and ORF3.
Zoya Shafat   +3 more
doaj   +1 more source

Patterns and influencing factor of synonymous codon usage in porcine circovirus

open access: yesVirology Journal, 2012
Background Analysis of codon usage can reveal much about the molecular evolution of the viruses. Nevertheless, little information about synonymous codon usage pattern of porcine circovirus (PCV) genome in the process of its evolution is available.
LIU Xin-sheng   +3 more
doaj   +1 more source

Comparative analysis of codon usage between Gossypium hirsutum and G. barbadense mitochondrial genomes

open access: yesMitochondrial DNA. Part B. Resources, 2020
Gossypium hirsutum and G. barbadense mitochondrial genomes were analyzed to understand the factors shaping codon usage. While most analyses of codon usage suggest minimal to no bias, nucleotide composition, specifically GC content, was significantly ...
Zhiwen Chen   +10 more
doaj   +1 more source

A code within the genetic code: codon usage regulates co-translational protein folding

open access: yesCell Communication and Signaling, 2020
The genetic code is degenerate, and most amino acids are encoded by two to six synonymous codons. Codon usage bias, the preference for certain synonymous codons, is a universal feature of all genomes examined.
Yi Liu
doaj   +1 more source

Codon usage in plant genes [PDF]

open access: yesNucleic Acids Research, 1989
We have examined codon bias in 207 plant gene sequences collected from Genbank and the literature. When this sample was further divided into 53 monocot and 154 dicot genes, the pattern of relative use of synonymous codons was shown to differ between these taxonomic groups, primarily in the use of G + C in the degenerate third base.
E E, Murray, J, Lotzer, M, Eberle
openaire   +2 more sources

Analysis of synonymous codon usage in Hepatitis A virus

open access: yesVirology Journal, 2011
Background Hepatitis A virus is the causative agent of type A viral hepatitis, which causes occasional acute hepatitis. Nevertheless, little information about synonymous codon usage pattern of HAV genome in the process of its evolution is available.
Ma Lina   +8 more
doaj   +1 more source

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