Results 11 to 20 of about 1,577,940 (309)
Research Progress of Coenzyme Q in Diabetes Mellitus and Its Common Complications [PDF]
Diabetes, Metabolic Syndrome and ObesityJingdong Xia,1,2 Xiudan Li,1,2 Chunying Bai,2 Xuchen Han1 1Affiliated Hospital of Chifeng University, Chifeng, The Inner Mongol Autonomous Region, Chifeng, People’s Republic of China; 2Key Laboratory of Research on Human Genetic Diseases at Universities ...
Xia J, Li X, Bai C, Han X
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Mitochondrial Coenzyme Q Redox Homeostasis and Reactive Oxygen Species Production
Frontiers in Bioscience-Landmark, 2023 Mitochondrial coenzyme Q (mtQ) of the inner mitochondrial membrane is a redox active mobile carrier in the respiratory chain that transfers electrons between reducing dehydrogenases and oxidizing pathway(s). mtQ is also involved in mitochondrial reactive
Wieslawa Jarmuszkiewicz +4 more
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In vitro construction of the COQ metabolon unveils the molecular determinants of coenzyme Q biosynthesis. [PDF]
Nat CatalMetabolons are protein assemblies that perform a series of reactions in a metabolic pathway. However, the general importance and aptitude of metabolons for enzyme catalysis remain poorly understood.
Nicoll CR +7 more
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An ETFDH-driven metabolon supports OXPHOS efficiency in skeletal muscle by regulating coenzyme Q homeostasis. [PDF]
Nat MetabCoenzyme Q (Q) is a key lipid electron transporter, but several aspects of its biosynthesis and redox homeostasis remain undefined. Various flavoproteins reduce ubiquinone (oxidized form of Q) to ubiquinol (QH2); however, in eukaryotes, only oxidative ...
Herrero Martín JC +11 more
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Frontiers in Physiology, 2017 Coenzyme Q is a lipid that participates to important physiological functions. Coenzyme Q is synthesized in multiple steps from the precursor 4-hydroxybenzoic acid.
Fabien Pierrel
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COQ8A-Ataxia as a Manifestation of Primary Coenzyme Q Deficiency [PDF]
Metabolites, 2022 COQ8A-ataxia is a mitochondrial disease in which a defect in coenzyme Q10 synthesis leads to dysfunction of the respiratory chain. The disease is usually present as childhood-onset progressive ataxia with developmental regression and cerebellar atrophy ...
Justyna Paprocka +3 more
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Coenzyme Q redox, signalling and longevity. [PDF]
Free Radical Biology and Medicine, 2021 Mitochondria are the powerhouses of the cell. They produce a significant amount of the energy we need to grow, survive and reproduce. The same system that generates energy in the form of ATP also produces Reactive Oxygen Species (ROS).
Filippo Scialó, A. Sanz
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Endogenous coenzyme Q content and exogenous bioavailability in D. melanogaster [PDF]
HeliyonDevelopment and aging significantly impact the cellular levels of Coenzyme Q (CoQ), which is associated with both pathological and physiological conditions.
Ilenia Cirilli +6 more
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The role of Coenzyme Q10 in statin-associated myopathy [PDF]
Electronic Physician, 2009 Statins, or 3-hydroxyl-3-methylglutaryl coenzyme HMG-CoA reductase inhibitors, are cholesterol-lowering drugs which are frequently used in the primary and secondary prevention of coronary artery disease.
Sanjay Kalra +4 more
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Contact, 2019 Loss of the endoplasmic reticulum (ER)-mitochondria encounter structure (ERMES) complex that resides in contact sites between the yeast ER and mitochondria leads to impaired respiration; however, the reason for that is not clear.
Michal Eisenberg-Bord +9 more
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