Results 31 to 40 of about 1,766,693 (250)

The effect of coenzyme Q and selenium on kidney in rats with partial unilateral ureteral obstruction

open access: yesUrology Research and Practice, 2019
Objective: In this study, we aimed to investigate the antioxidant effects of selenium and coenzyme Q on renal damage in a partial unilateral ureteral obstruction (PUUO) in a rat model.
Mustafa Koray Kırdağ   +6 more
doaj   +1 more source

In vitro evaluation of coenzyme Q10 on primary fibroblast culture

open access: yesMajalah Kedokteran Gigi Indonesia, 2023
Chronic inflammation in periodontitis results in continuous production of Reactive Oxygen Species (ROS), so the levels are excessive, causing destruction of the gingiva, periodontal ligament, and alveolar bone through a variety of mechanisms including ...
Dahlia Herawati
doaj   +1 more source

Exogenous coenzyme Q10 modulates MMP-2 activity in MCF-7 cell line as a breast cancer cellular model

open access: yesNutrition Journal, 2010
Background/Aims Matrix Metalloproteinases 2 is a key molecule in cellular invasion and metastasis. Mitochondrial ROS has been established as a mediator of MMP activity. Coenzyme Q10 contributes to intracellular ROS regulation.
Mirmiranpour Hossein   +6 more
doaj   +1 more source

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

open access: yesHepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog   +12 more
wiley   +1 more source

Skeletal muscle mitochondrial bioenergetics and associations with myostatin genotypes in the Thoroughbred horse. [PDF]

open access: yesPLoS ONE, 2017
Variation in the myostatin (MSTN) gene has been reported to be associated with race distance, body composition and skeletal muscle fibre composition in the horse.
Mary F Rooney   +3 more
doaj   +1 more source

Properties of Coenzyme Q derivatives obtained via reaction from Coenzyme Q-0 in alkaline media [PDF]

open access: yes, 2013
Novel set of coenzyme Q-like hydroxilated deriavtives have been synthesized via reaction of COenzyme Q-0 in strong alkaline media. The novel compounds show pronounced antioxidative and metal binding properties toward earth-alkaline cations.
Naumova, Galaba   +2 more
core   +1 more source

Preparation of Key Intermediates for the Syntheses of Coenzyme Q10 and Derivatives by Cross-Metathesis Reactions

open access: yesMolecules, 2020
An alternative catalytic strategy for the preparation of benzylmethacrylate esters, key intermediates in the synthesis of coenzyme Q10 and derivatives, was reported.
Trang Nguyen, Hung Mac, Phong Pham
doaj   +1 more source

Coenzyme Q supplementation in pulmonary arterial hypertension

open access: yesRedox Biology, 2014
Mitochondrial dysfunction is a fundamental abnormality in the vascular endothelium and smooth muscle of patients with pulmonary arterial hypertension (PAH). Because coenzyme Q (CoQ) is essential for mitochondrial function and efficient oxygen utilization
Jacqueline Sharp   +8 more
doaj   +1 more source

Compound heterozygous inheritance of two novel COQ2 variants results in familial coenzyme Q deficiency

open access: yesOrphanet Journal of Rare Diseases, 2020
Background Primary coenzyme Q10 deficiency is a rare disease that results in diverse and variable clinical manifestations. Nephropathy, myopathy and neurologic involvement are commonly associated, however retinopathy has also been observed with certain ...
Aliaa H. Abdelhakim   +12 more
doaj   +1 more source

The distribution of coenzyme Q in the tissues of the gravid ewe and fetus

open access: yes, 1969
Data on coenzyme Q tissue concentrations were obtained from 26 ewes and their fetuses from 50 days postconception to term. Coenzyme Q concentrations were low in early embryonic life. A significant increase was observed in coenzyme Q concentration in the
M. Hidiroglou
core   +1 more source

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