Results 11 to 20 of about 548 (205)

Impact of Chemical Analogs of 4-Hydroxybenzoic Acid on Coenzyme Q Biosynthesis: From Inhibition to Bypass of Coenzyme Q Deficiency

open access: yesFrontiers in Physiology, 2017
Coenzyme Q is a lipid that participates to important physiological functions. Coenzyme Q is synthesized in multiple steps from the precursor 4-hydroxybenzoic acid.
Fabien Pierrel
exaly   +3 more sources

The Ubiquitous and Multifaceted Coenzyme Q

open access: yesAntioxidants
Coenzyme Q10 (CoQ10) is composed of a benzoquinone ring and an isoprenoid side chain attached to carbon 3 of the ring [...]
Luca Tiano, Plácido Navas
doaj   +4 more sources

Ubisol-Q10, a Nanomicellar and Water-Dispersible Formulation of Coenzyme-Q10 as a Potential Treatment for Alzheimer’s and Parkinson’s Disease

open access: yesAntioxidants, 2021
The world continues a desperate search for therapies that could bring hope and relief to millions suffering from progressive neurodegenerative diseases such as Alzheimer’s (AD) and Parkinson’s (PD).
Darcy Wear   +5 more
doaj   +1 more source

How plants synthesize coenzyme Q

open access: yesPlant Communications, 2022
Coenzyme Q (CoQ) is a conserved redox-active lipid that has a wide distribution across the domains of life. CoQ plays a key role in the oxidative electron transfer chain and serves as a crucial antioxidant in cellular membranes.
Jing-Jing Xu   +3 more
doaj   +1 more source

Coenzyme Q at the Hinge of Health and Metabolic Diseases

open access: yesAntioxidants, 2021
Coenzyme Q is a unique lipidic molecule highly conserved in evolution and essential to maintaining aerobic metabolism. It is endogenously synthesized in all cells by a very complex pathway involving a group of nuclear genes that share high homology among
Juan Diego Hernández-Camacho   +4 more
doaj   +1 more source

Coenzyme Q in Asthma [PDF]

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2015
To the Editor: Asthma is a chronic inflammatory disease characterized by an increase of reactive oxygen and nitrogen species production in the airways (1–3). Oxidative stress has been proportionately linked to the severity of the disease (2, 3). The lung has effective, well-integrated antioxidant systems to combat oxidative and nitrative injury ...
Suzy A A, Comhair   +5 more
openaire   +2 more sources

Biosynthesis, Deficiency, and Supplementation of Coenzyme Q

open access: yesAntioxidants, 2023
Originally identified as a key component of the mitochondrial respiratory chain, Coenzyme Q (CoQ or CoQ10 for human tissues) has recently been revealed to be essential for many different redox processes, not only in the mitochondria, but elsewhere within
Carmine Staiano   +6 more
doaj   +1 more source

Microarray and qPCR Analysis of Mitochondrial Metabolism Activation during Prenatal and Early Postnatal Development in Rats and Humans with Emphasis on CoQ10 Biosynthesis

open access: yesBiology, 2021
At the end of the mammalian intra-uterine foetal development, a rapid switch from glycolytic to oxidative metabolism must proceed. Using microarray techniques, qPCR, enzyme activities and coenzyme Q content measurements, we describe perinatal ...
Jana Krizova   +7 more
doaj   +1 more source

Antihypoxic Activities of Coenzyme Q and Folic Acid in Asphyctic, Hemic, and Circulatory Hypoxia Models in Mice [PDF]

open access: yesJournal of Mazandaran University of Medical Sciences, 2023
Background and purpose: Hypoxia is a decrease in oxygen levels of body tissues which can lead to body function impairment. Coenzyme Q and folic acid are well-known drugs with distinctive antioxidant and anti-ischemic activities, but, nothing is known ...
Mahsa Modammadyan   +3 more
doaj  

Decreased Concentration of Fibroblast Growth Factor 23 (FGF-23) as a Result of Supplementation with Selenium and Coenzyme Q10 in an Elderly Swedish Population: A Sub-Analysis

open access: yesCells, 2022
There is a reduced intake of selenium in many countries due to low levels of selenium in the soil. This results in an increased cardiovascular risk.
Urban Alehagen   +3 more
doaj   +1 more source

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