Results 21 to 30 of about 42,231 (222)

Coenzyme Q and the Respiratory Chain: Coenzyme Q Pool and Mitochondrial Supercomplexes [PDF]

open access: yesMolecular Syndromology, 2014
Two alternative models of organization of the mitochondrial electron transport chain (mETC) have been alternatively favored or questioned by the accumulation evidences of different sources, the solid model or the random collision model. Both agree in the number of respiratory complexes (I-IV) that participate in the mETC, but while the random collision
José Antonio, Enriquez, Giorgio, Lenaz
openaire   +2 more sources

Coenzyme Q. LX. Vitamin-Like Activity of Coenzyme Q.

open access: yesExperimental Biology and Medicine, 1965
SummaryVitamin-like activity for hexahydrocoenzyme Q4 in the dystrophic rabbit is demonstrated. This activity for a quinone member of the CoQ group is comparable to the activity of α-tocopherol and CoQ4-chromanol which has previously been demonstrated. By contrast, a sample of 2,3,5-trimethyl-6-phytylbenzoquinone, which was free of contamination with α-
J L, SMITH, H W, MOORE, K, FOLKERS
openaire   +2 more sources

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

open access: yesHepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog   +12 more
wiley   +1 more source

Effect of Coenzyme Q10 Supplementation on Testosterone

open access: yesBiomolecules, 2018
Enhancing testosterone production in males is a continuous research direction for many scientists in the field, due to its role as a principal sex hormone and as a crucial modulator of well-being and general health in humans.
Saleem Ali Banihani
doaj   +1 more source

The effect of coenzyme Q and selenium on kidney in rats with partial unilateral ureteral obstruction

open access: yesUrology Research and Practice, 2019
Objective: In this study, we aimed to investigate the antioxidant effects of selenium and coenzyme Q on renal damage in a partial unilateral ureteral obstruction (PUUO) in a rat model.
Mustafa Koray Kırdağ   +6 more
doaj   +1 more source

In vitro evaluation of coenzyme Q10 on primary fibroblast culture

open access: yesMajalah Kedokteran Gigi Indonesia, 2023
Chronic inflammation in periodontitis results in continuous production of Reactive Oxygen Species (ROS), so the levels are excessive, causing destruction of the gingiva, periodontal ligament, and alveolar bone through a variety of mechanisms including ...
Dahlia Herawati
doaj   +1 more source

Exogenous coenzyme Q10 modulates MMP-2 activity in MCF-7 cell line as a breast cancer cellular model

open access: yesNutrition Journal, 2010
Background/Aims Matrix Metalloproteinases 2 is a key molecule in cellular invasion and metastasis. Mitochondrial ROS has been established as a mediator of MMP activity. Coenzyme Q10 contributes to intracellular ROS regulation.
Mirmiranpour Hossein   +6 more
doaj   +1 more source

Skeletal muscle mitochondrial bioenergetics and associations with myostatin genotypes in the Thoroughbred horse. [PDF]

open access: yesPLoS ONE, 2017
Variation in the myostatin (MSTN) gene has been reported to be associated with race distance, body composition and skeletal muscle fibre composition in the horse.
Mary F Rooney   +3 more
doaj   +1 more source

Preparation of Key Intermediates for the Syntheses of Coenzyme Q10 and Derivatives by Cross-Metathesis Reactions

open access: yesMolecules, 2020
An alternative catalytic strategy for the preparation of benzylmethacrylate esters, key intermediates in the synthesis of coenzyme Q10 and derivatives, was reported.
Trang Nguyen, Hung Mac, Phong Pham
doaj   +1 more source

Coenzyme Q redox signalling and longevity [PDF]

open access: yesFree Radical Biology and Medicine, 2021
Mitochondria are the powerhouses of the cell. They produce a significant amount of the energy we need to grow, survive and reproduce. The same system that generates energy in the form of ATP also produces Reactive Oxygen Species (ROS). Mitochondrial Reactive Oxygen Species (mtROS) were considered for many years toxic by-products of metabolism ...
Scialo, Filippo, Sanz, Alberto
openaire   +4 more sources

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