Results 21 to 30 of about 1,577,940 (309)
Coenzyme Q deficiency causes impairment of the sulfide oxidation pathway
EMBO Molecular Medicine, 2016 Coenzyme Q (CoQ) is an electron acceptor for sulfide‐quinone reductase (SQR), the first enzyme of the hydrogen sulfide oxidation pathway. Here, we show that lack of CoQ in human skin fibroblasts causes impairment of hydrogen sulfide oxidation ...
Marcello Ziosi +15 more
doaj +2 more sources
Antioxidants, 2021 The world continues a desperate search for therapies that could bring hope and relief to millions suffering from progressive neurodegenerative diseases such as Alzheimer’s (AD) and Parkinson’s (PD).
Darcy Wear +5 more
doaj +1 more source
The mitochondrial coenzyme Q junction and complex III: biochemistry and pathophysiology
The FEBS Journal, 2021 Coenzyme Q (CoQ, ubiquinone) is the electron‐carrying lipid in the mitochondrial electron transport system (ETS). In mammals, it serves as the electron acceptor for nine mitochondrial inner membrane dehydrogenases.
Rishi Banerjee +2 more
semanticscholar +1 more source
The Roles of Coenzyme Q in Disease: Direct and Indirect Involvement in Cellular Functions
International Journal of Molecular Sciences, 2021 Coenzyme Q (CoQ) is a key component of the respiratory chain of all eukaryotic cells. Its function is closely related to mitochondrial respiration, where it acts as an electron transporter.
Francesco Pallotti +3 more
semanticscholar +1 more source
Free Radical Biology & Medicine, 2021 Primary Coenzyme Q (CoQ) deficiencies are clinically heterogeneous conditions and lack clear genotype-phenotype correlations, complicating diagnosis and prognostic assessment.
María Alcázar-Fabra +3 more
semanticscholar +1 more source
Recent advances in the metabolic pathways and microbial production of coenzyme Q
World Journal of Microbiology & Biotechnology, 2022 Coenzyme Q (CoQ) serves as an electron carrier in aerobic respiration and has become an interesting target for biotechnological production due to its antioxidative effect and benefits in supplementation to patients with various diseases.
F. Pierrel +4 more
semanticscholar +1 more source
Biology, 2021 At the end of the mammalian intra-uterine foetal development, a rapid switch from glycolytic to oxidative metabolism must proceed. Using microarray techniques, qPCR, enzyme activities and coenzyme Q content measurements, we describe perinatal ...
Jana Krizova +7 more
doaj +1 more source
Antihypoxic Activities of Coenzyme Q and Folic Acid in Asphyctic, Hemic, and Circulatory Hypoxia Models in Mice [PDF]
Journal of Mazandaran University of Medical Sciences, 2023 Background and purpose: Hypoxia is a decrease in oxygen levels of body tissues which can lead to body function impairment. Coenzyme Q and folic acid are well-known drugs with distinctive antioxidant and anti-ischemic activities, but, nothing is known ...
Mahsa Modammadyan +3 more
doaj
Cells, 2022 There is a reduced intake of selenium in many countries due to low levels of selenium in the soil. This results in an increased cardiovascular risk.
Urban Alehagen +3 more
doaj +1 more source
Role of Coenzyme Q10 in Health and Disease: An Update on the Last 10 Years (2010–2020)
Antioxidants, 2021 The present review focuses on preclinical and clinical studies conducted in the last decade that contribute to increasing knowledge on Coenzyme Q10’s role in health and disease.
Ilenia Cirilli +8 more
doaj +1 more source