Results 31 to 40 of about 1,577,940 (309)
Metabolites, 2021 Coenzyme Q (ubiquinone or CoQ) is a conserved polyprenylated lipid essential for mitochondrial respiration. CoQ is composed of a redox-active benzoquinone ring and a long polyisoprenyl tail that serves as a membrane anchor.
Lucía Fernández-Del-Río, C. Clarke
semanticscholar +1 more source
American Journal of Respiratory and Critical Care Medicine, 2015 To the Editor: Asthma is a chronic inflammatory disease characterized by an increase of reactive oxygen and nitrogen species production in the airways (1–3). Oxidative stress has been proportionately linked to the severity of the disease (2, 3). The lung has effective, well-integrated antioxidant systems to combat oxidative and nitrative injury ...
Suzy A A, Comhair +5 more
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Бюллетень сибирской медицины, 2022 Aim. To evaluate the functional state of mitochondria isolated from peripheral blood mononuclear leukocytes using flow cytometry in patients with chronic heart failure receiving ubidecarenone (coenzyme Q).Materials and methods.
O. A. Lobanova +4 more
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Cooperation between CYB5R3 and NOX4 via coenzyme Q mitigates endothelial inflammation
bioRxiv, 2021 NADPH oxidase 4 (NOX4) regulates endothelial inflammation by producing reactive oxygen species. Since coenzyme Q (CoQ) mimics affect NOX4 activity, we hypothesize that cytochrome b5 reductase 3 (CYB5R3), a CoQ reductase abundant in vascular endothelial ...
S. Yuan +18 more
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PLoS ONE, 2020 Saccharomyces cerevisiae Coq8 is a member of the ancient UbiB atypical protein kinase family. Coq8, and its orthologs UbiB, ABC1, ADCK3, and ADCK4, are required for the biosynthesis of coenzyme Q in yeast, E. coli, A. thaliana, and humans.
Agape M Awad +6 more
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Coenzyme Q. LX. Vitamin-Like Activity of Coenzyme Q.
Experimental Biology and Medicine, 1965 SummaryVitamin-like activity for hexahydrocoenzyme Q4 in the dystrophic rabbit is demonstrated. This activity for a quinone member of the CoQ group is comparable to the activity of α-tocopherol and CoQ4-chromanol which has previously been demonstrated. By contrast, a sample of 2,3,5-trimethyl-6-phytylbenzoquinone, which was free of contamination with α-
J L, SMITH, H W, MOORE, K, FOLKERS
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Clinical syndromes associated with Coenzyme Q10 deficiency. [PDF]
, 2018 Primary Coenzyme Q deficiencies represent a group of rare conditions caused by mutations in one of the genes required in its biosynthetic pathway at the enzymatic or regulatory level.
Alc\ue1zar-Fabra, Maria +2 more
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Defining intermediates and redundancies in coenzyme Q precursor biosynthesis
Journal of Biological Chemistry, 2021 Coenzyme Q (CoQ), a redox-active lipid essential for oxidative phosphorylation, is synthesized by virtually all cells, but how eukaryotes make the universal CoQ head group precursor 4-hydroxybenzoate (4-HB) from tyrosine is unknown.
Kyle P. Robinson +6 more
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Calcium Binding and Transport by Coenzyme Q [PDF]
, 2011 Coenzyme Q10 (CoQ10) is one of the essential components of the mitochondrial electron-transport chain (ETC) with the primary function to transfer electrons along and protons across the inner mitochondrial membrane (IMM).
Bogeski, Ivan +6 more
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Coenzyme Q homeostasis in aging: response to non-genetic interventions.
Free Radical Biology & Medicine, 2021 Coenzyme Q (CoQ) is a key component for many essential metabolic and antioxidant activities in cells in mitochondria and cell membranes. Mitochondrial dysfunction is one of the hallmarks of aging and age-related diseases.
G. López-Lluch
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