Results 51 to 60 of about 1,577,940 (309)

Ubiquinone (Coenzyme Q) in Insects [PDF]

open access: yesNature, 1960
Lester and Crane1 found that while tissues of vertebrates contain mostly the Q 10-homologue of ubiquinone (coenzyme Q), certain insects, notably the house-fly, Musca domestica, and the cabbage white butterfly, Pieris rapae, are characterized by the presence of the Q 9 homologue, that is, a ubiquinone with a side-chain of 9, instead of 10, isoprenoid ...
J, HELLER, L, SZARKOWSKA, H, MICHALEK
openaire   +2 more sources

Preparation of Key Intermediates for the Syntheses of Coenzyme Q10 and Derivatives by Cross-Metathesis Reactions

open access: yesMolecules, 2020
An alternative catalytic strategy for the preparation of benzylmethacrylate esters, key intermediates in the synthesis of coenzyme Q10 and derivatives, was reported.
Trang Nguyen, Hung Mac, Phong Pham
doaj   +1 more source

Remnants of an ancient metabolism without phosphate [PDF]

open access: yes, 2017
Phosphate is essential for all living systems, serving as a building block of genetic and metabolic machinery. However, it is unclear how phosphate could have assumed these central roles on primordial Earth, given its poor geochemical accessibility.
Goldford, Joshua E.   +3 more
core   +1 more source

Coenzyme Q and mitochondrial disease [PDF]

open access: yesDevelopmental Disabilities Research Reviews, 2010
AbstractCoenzyme Q10 (CoQ10) is an essential electron carrier in the mitochondrial respiratory chain and an important antioxidant. Deficiency of CoQ10 is a clinically and molecularly heterogeneous syndrome, which, to date, has been found to be autosomal recessive in inheritance and generally responsive to CoQ10 supplementation.
Catarina M, Quinzii, Michio, Hirano
openaire   +2 more sources

Coenzyme Q supplementation in pulmonary arterial hypertension

open access: yesRedox Biology, 2014
Mitochondrial dysfunction is a fundamental abnormality in the vascular endothelium and smooth muscle of patients with pulmonary arterial hypertension (PAH). Because coenzyme Q (CoQ) is essential for mitochondrial function and efficient oxygen utilization
Jacqueline Sharp   +8 more
doaj   +1 more source

Compound heterozygous inheritance of two novel COQ2 variants results in familial coenzyme Q deficiency

open access: yesOrphanet Journal of Rare Diseases, 2020
Background Primary coenzyme Q10 deficiency is a rare disease that results in diverse and variable clinical manifestations. Nephropathy, myopathy and neurologic involvement are commonly associated, however retinopathy has also been observed with certain ...
Aliaa H. Abdelhakim   +12 more
doaj   +1 more source

Antioxidant Supplementation in the Treatment of Aging-Associated Diseases [PDF]

open access: yes, 2016
Oxidative stress is generally considered as the consequence of an imbalance between pro- and antioxidants species, which often results into indiscriminate and global damage at the organismal level.
Conti, V   +7 more
core   +2 more sources

A Case of Statin-Associated Autoimmune Myopathy. [PDF]

open access: yes, 2017
A 70-year-old previously independent man developed progressive proximal leg weakness resulting in a fall at home suffering traumatic brain injury. He was prescribed a statin medication two years prior, but this was discontinued on admission to the ...
Dokukin, Andrei N   +6 more
core   +3 more sources

Composition and Antioxidant Properties of Spanish Extra Virgin Olive Oil Regarding Cultivar, Harvest Year and Crop Stage

open access: yesAntioxidants, 2019
The health benefits of extra virgin olive oil (EVOO) are related to its chemical composition and the presence of bioactive compounds with antioxidant properties.
Thays Helena Borges   +5 more
doaj   +1 more source

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

open access: yesHepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog   +12 more
wiley   +1 more source

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