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Dynamic Combinatorial Chemistry [PDF]

open access: yesChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Corbett, Peter T.,   +6 more
core   +6 more sources

Combinatorial chemistry in drug discovery. [PDF]

open access: yesCurr Opin Chem Biol, 2017
Several combinatorial methods have been developed to create focused or diverse chemical libraries with a wide range of linear or macrocyclic chemical molecules: peptides, non-peptide oligomers, peptidomimetics, small-molecules, and natural product-like organic molecules.
Liu R, Li X, Lam KS.
europepmc   +8 more sources

Protein-Directed Dynamic Combinatorial Chemistry: A Guide to Protein Ligand and Inhibitor Discovery [PDF]

open access: yesMolecules, 2016
Protein-directed dynamic combinatorial chemistry is an emerging technique for efficient discovery of novel chemical structures for binding to a target protein.
Renjie Huang, Ivanhoe K. H. Leung
doaj   +3 more sources

Combinatorial Chemistry

open access: yesCHIMIA, 2000
In many areas of chemical synthesis, drug discovery, and materials research, combinatorial approaches are becoming more and more important. One of the most serious bottlenecks in this area is the chemical analysis and screening of the products ...
Renato Zenobi
doaj   +4 more sources

Structurally divergent dynamic combinatorial chemistry on racemic mixtures [PDF]

open access: yesNature Communications, 2020
Structurally divergent reactions on racemic mixtures, which produce distinct chemical species from an enantiomeric mixture, are extremely rare in the literature.
Tiberiu-M. Gianga, G. Dan Pantoș
doaj   +2 more sources

Mesofluidic devices for DNA-programmed combinatorial chemistry. [PDF]

open access: yesPLoS ONE, 2012
Hybrid combinatorial chemistry strategies that use DNA as an information-carrying medium are proving to be powerful tools for molecular discovery. In order to extend these efforts, we present a highly parallel format for DNA-programmed chemical library ...
Rebecca M Weisinger   +3 more
doaj   +2 more sources

N-Acylation in combinatorial chemistry

open access: yesARKIVOC, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Alan R. Katritzky   +2 more
doaj   +4 more sources

The Supramolecular Chemistry of Proteins – Protein Epitope Mimetics Prepared Using Combinatorial Biomimetic Chemistry

open access: diamondCHIMIA, 2000
Some new approaches are described for the synthesis of protein epitope mimetics, in particular, mimics of ?-hairpin structures found in antibodies, growth factors, and other proteins involved in macromolecular recognition in Nature. The mimetics
Luyong Jiang   +3 more
doaj   +3 more sources

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