Results 11 to 20 of about 1,152,460 (369)
Structurally divergent dynamic combinatorial chemistry on racemic mixtures [PDF]
Nature Communications, 2020 Structurally divergent reactions on racemic mixtures, which produce distinct chemical species from an enantiomeric mixture, are extremely rare in the literature.
Tiberiu-M. Gianga, G. Dan Pantoș
doaj +2 more sources
Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin: Fragment-Based Drug Design Facilitated by Dynamic Combinatorial Chemistry. [PDF]
Angew Chem Int Ed Engl, 2016 Fragment‐based drug design (FBDD) affords active compounds for biological targets. While there are numerous reports on FBDD by fragment growing/optimization, fragment linking has rarely been reported.
Mondal M +5 more
europepmc +2 more sources
Dynamic combinatorial libraries: from exploring molecular recognition to systems chemistry. [PDF]
Journal of the American Chemical Society, 2013 Dynamic combinatorial chemistry (DCC) is a subset of combinatorial chemistry where the library members interconvert continuously by exchanging building blocks with each other.
Jianwei Li, P. Nowak, S. Otto
semanticscholar +4 more sources
Mesofluidic devices for DNA-programmed combinatorial chemistry. [PDF]
PLoS ONE, 2012 Hybrid combinatorial chemistry strategies that use DNA as an information-carrying medium are proving to be powerful tools for molecular discovery. In order to extend these efforts, we present a highly parallel format for DNA-programmed chemical library ...
Rebecca M Weisinger +3 more
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N-Acylation in combinatorial chemistry
ARKIVOC, 2004 AbstractFor Abstract see ChemInform Abstract in Full Text.
Alan R. Katritzky +2 more
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CHIMIA, 2000 Some new approaches are described for the synthesis of protein epitope mimetics, in particular, mimics of ?-hairpin structures found in antibodies, growth factors, and other proteins involved in macromolecular recognition in Nature. The mimetics
Luyong Jiang +3 more
doaj +3 more sources
Machine learning in combinatorial polymer chemistry
Nature Reviews Materials, 2021 Adam J Gormley, Michael A Webb
exaly +2 more sources
Transfer RNA modifications: nature's combinatorial chemistry playground. [PDF]
Wiley Interdiscip Rev RNA, 2013 Jackman JE, Alfonzo JD.
europepmc +2 more sources
Beilstein Journal of Organic Chemistry, 2021 A base- and catalyst-free C(sp3)–H allylic alkylation of 2-alkylpyridines with Morita–Baylis–Hillman (MBH) carbonates is described. A plausible mechanism of the reaction might involve a tandem SN2’ type nucleophilic substitution followed by an aza-Cope ...
Siyu Wang +5 more
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