Results 21 to 30 of about 1,058,395 (336)

Combinatorial Chemistry

open access: yesCHIMIA, 2000
In many areas of chemical synthesis, drug discovery, and materials research, combinatorial approaches are becoming more and more important. One of the most serious bottlenecks in this area is the chemical analysis and screening of the products ...
Renato Zenobi
doaj   +4 more sources

Ternary resin-bound Dynamic Combinatorial Chemistry. [PDF]

open access: yesChem Commun (Camb), 2012
The ability to carry out simultaneous orthogonal exchange chemistries has opened new opportunities for increasing the numerical and structural diversity accessible to Dynamic Combinatorial Chemistry.
Gromova AV, Ciszewski JM, Miller BL.
europepmc   +2 more sources

The Supramolecular Chemistry of Proteins – Protein Epitope Mimetics Prepared Using Combinatorial Biomimetic Chemistry

open access: diamondCHIMIA, 2000
Some new approaches are described for the synthesis of protein epitope mimetics, in particular, mimics of ?-hairpin structures found in antibodies, growth factors, and other proteins involved in macromolecular recognition in Nature. The mimetics
Luyong Jiang   +3 more
doaj   +3 more sources

N-Acylation in combinatorial chemistry

open access: yesARKIVOC, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Alan R. Katritzky   +2 more
doaj   +4 more sources

Direct C(sp3)–H allylation of 2-alkylpyridines with Morita–Baylis–Hillman carbonates via a tandem nucleophilic substitution/aza-Cope rearrangement

open access: yesBeilstein Journal of Organic Chemistry, 2021
A base- and catalyst-free C(sp3)–H allylic alkylation of 2-alkylpyridines with Morita–Baylis–Hillman (MBH) carbonates is described. A plausible mechanism of the reaction might involve a tandem SN2’ type nucleophilic substitution followed by an aza-Cope ...
Siyu Wang   +5 more
doaj   +1 more source

Live-Cell-Templated Dynamic Combinatorial Chemistry.

open access: yesAngewandte Chemie, 2020
Dynamic covalent chemistry combines in a single step the screening and synthesis of ligands for biomolecular recognition. To that, a chemical entity is used as template within a dynamic combinatorial library of interconverting species, so that the ...
D. Carbajo   +3 more
semanticscholar   +1 more source

Expression and Purification of Glycosyltransferase DnmS from Streptomyces peucetius ATCC 27952 and Study on Catalytic Characterization of Its Reverse Glycosyltransferase Reaction

open access: yesMicroorganisms, 2023
Anthracyclines are an important class of natural antitumor drugs. They have a conservative aromatic tetracycline backbone that is substituted with different deoxyglucoses.
Liyan Yang   +5 more
doaj   +1 more source

AlgM4: A New Salt-Activated Alginate Lyase of the PL7 Family with Endolytic Activity

open access: yesMarine Drugs, 2018
Alginate lyases are a group of enzymes that catalyze the depolymerization of alginates into oligosaccharides or monosaccharides. These enzymes have been widely used for a variety of purposes, such as producing bioactive oligosaccharides, controlling the ...
Guiyuan Huang   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy