Results 21 to 30 of about 1,058,395 (336)
In many areas of chemical synthesis, drug discovery, and materials research, combinatorial approaches are becoming more and more important. One of the most serious bottlenecks in this area is the chemical analysis and screening of the products ...
Renato Zenobi
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Ternary resin-bound Dynamic Combinatorial Chemistry. [PDF]
The ability to carry out simultaneous orthogonal exchange chemistries has opened new opportunities for increasing the numerical and structural diversity accessible to Dynamic Combinatorial Chemistry.
Gromova AV, Ciszewski JM, Miller BL.
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Some new approaches are described for the synthesis of protein epitope mimetics, in particular, mimics of ?-hairpin structures found in antibodies, growth factors, and other proteins involved in macromolecular recognition in Nature. The mimetics
Luyong Jiang+3 more
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N-Acylation in combinatorial chemistry
AbstractFor Abstract see ChemInform Abstract in Full Text.
Alan R. Katritzky+2 more
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Transfer RNA modifications: nature's combinatorial chemistry playground. [PDF]
Jackman JE, Alfonzo JD.
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A base- and catalyst-free C(sp3)–H allylic alkylation of 2-alkylpyridines with Morita–Baylis–Hillman (MBH) carbonates is described. A plausible mechanism of the reaction might involve a tandem SN2’ type nucleophilic substitution followed by an aza-Cope ...
Siyu Wang+5 more
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Live-Cell-Templated Dynamic Combinatorial Chemistry.
Dynamic covalent chemistry combines in a single step the screening and synthesis of ligands for biomolecular recognition. To that, a chemical entity is used as template within a dynamic combinatorial library of interconverting species, so that the ...
D. Carbajo+3 more
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Anthracyclines are an important class of natural antitumor drugs. They have a conservative aromatic tetracycline backbone that is substituted with different deoxyglucoses.
Liyan Yang+5 more
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AlgM4: A New Salt-Activated Alginate Lyase of the PL7 Family with Endolytic Activity
Alginate lyases are a group of enzymes that catalyze the depolymerization of alginates into oligosaccharides or monosaccharides. These enzymes have been widely used for a variety of purposes, such as producing bioactive oligosaccharides, controlling the ...
Guiyuan Huang+7 more
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