Results 61 to 70 of about 1,203,521 (299)

Teaching Presence: Co-Creating a Multi-National Online Learning Community in an Asynchronous Classroom

open access: yesOnline Learning, 2014
The pace of globalization coupled with growing institutional pursuit of online education means that online classes are increasingly composed of a multi-national, multi-ethnic, and multi-cultural student body.
Leanne Dzubinski
doaj   +1 more source

Inquiries into inquiry projects [PDF]

open access: yes, 2007
The projects developed by the research teams foster inquiry and leadership for the improvement of student learning and reflective teaching. They expand conceptions of learning and teaching by linking to the community, crossing disciplinary boundaries ...
Bruce, Bertram C., Graber, Kim
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Employing a Community of Inquiry Framework to Understand Graduate Students' Perceptions of Supports in Asynchronous Online Courses Focused on Assessment

open access: yesJournal of Human Services: Training, Research, and Practice, 2019
As universities increase the number of online course offerings, the quality of programs is often called into question. In many instances, student input is not solicited when devising online course offerings and faculty often lack the training needed to ...
Jessica A. Rueter   +2 more
doaj  

Reclaiming the ontological over the epistemological: A case study into a New Zealand Primary School disclosing an embodied culture of teacher inquiry

open access: yesNew Zealand Journal of Teachers' Work, 2016
This article presents case study research into a New Zealand Primary School enacting a very sophisticated whole school inquiry approach to grow teacher classroom professionalism and practice.
Andrew Bills, Bev Rogers, David Giles
doaj   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Learning Analytics for Communities of Inquiry

open access: yesJournal of Learning Analytics, 2014
This paper describes a doctoral research that focuses on the development of a learning analytics framework for inquiry-based digital learning. This research builds on the the Community of Inquiry model (CoI) as a foundation commonly used in research and practice of digital learning and teaching. Specifically, the main contributions of this research are:
Kovanovic, Vitomir   +2 more
openaire   +5 more sources

Exploring the value of a design for service approach to develop public services in the Community Voluntary Sector: a comparative analysis [PDF]

open access: yes, 2014
This paper presents the findings from two action research case studies that explore the value of using a ‘design for service’ approach to develop public services in the community voluntary sector (CVS).
Lievesley, Matthew   +2 more
core   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

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