Results 11 to 20 of about 125,024 (282)
Long Noncoding Competing Endogenous RNA Networks in Pancreatic Cancer [PDF]
Frontiers in Oncology, 2021 Pancreatic cancer (PC) is a highly malignant disease characterized by insidious onset, rapid progress, and poor therapeutic effects. The molecular mechanisms associated with PC initiation and progression are largely insufficient, hampering the ...
Guangbing Xiong +10 more
doaj +3 more sources
Competing Endogenous RNA Networks as Biomarkers in Neurodegenerative Diseases [PDF]
International Journal of Molecular Sciences, 2020 Protein aggregation is classically considered the main cause of neuronal death in neurodegenerative diseases (NDDs). However, increasing evidence suggests that alteration of RNA metabolism is a key factor in the etiopathogenesis of these complex disorders.
Leticia Moreno-García +2 more
exaly +4 more sources
A competing endogenous RNA network reveals key lncRNAs associated with sepsis [PDF]
Molecular Genetics & Genomic Medicine, 2021 Background This study set out to determine key lncRNAs correlated with sepsis via constructing competing endogenous RNA (ceRNA) network. Methods Three septic patients and three healthy controls were recruited to obtain lncRNA profiles in this current ...
Xuan Guo +6 more
doaj +3 more sources
Competing Endogenous RNA Network Analysis Reveals Pivotal ceRNAs in Adrenocortical Carcinoma [PDF]
Frontiers in Endocrinology, 2019 Objective: To construct ceRNA network and identify pivotal competing endogenous RNAs (ceRNAs) in adrenocortical carcinoma (ACC) using ceRNA network analysis.Methods: The RNA sequencing expression data of 77 ACCs in TCGA were obtained from GEPIA.
Weiwei Liang, Fangfang Sun
doaj +3 more sources
Bioinformatics analysis of long non-coding RNA-associated competing endogenous RNA network in schizophrenia [PDF]
Scientific Reports, 2021 Schizophrenia (SCZ) is a serious psychiatric condition with a 1% lifetime risk. SCZ is one of the top ten global causes of disabilities. Despite numerous attempts to understand the function of genetic factors in SCZ development, genetic components in SCZ
Hani Sabaie +7 more
doaj +3 more sources
Construction of circular RNA‐based competing endogenous RNA network in colon cancer
Precision Medical SciencesCircular RNAs (CircRNAs) are now under discussion as novel promising biomarkers for patients with various tumors. Our study aimed to identify circRNAs related to the progression of colon cancer and to further investigate their roles in the development of
Zhengyu Gu +3 more
doaj +2 more sources
Molecular Network-Based Identification of Competing Endogenous RNAs in Thyroid Carcinoma [PDF]
Genes, 2018 RNAs may act as competing endogenous RNAs (ceRNAs), a critical mechanism in determining gene expression regulations in many cancers. However, the roles of ceRNAs in thyroid carcinoma remains elusive. In this study, we have developed a novel pipeline called Molecular Network-based Identification of ceRNA (MNIceRNA) to identify ceRNAs in thyroid ...
Qi Dai, Min Tang, Yuhua Yao
exaly +3 more sources
Constructing a competing endogenous RNA network for osteoarthritis. [PDF]
Ann Transl Med, 2022 Osteoarthritis (OA) is one of the most common diseases in elderly people; however, the correlation between molecular alterations and the occurrence and progression of OA are still not well understood. We conducted this study to investigate the molecular changes in OA via the competing endogenous ribonucleic acid (ceRNA) network.We downloaded the ...
Hua SL +5 more
europepmc +4 more sources
Construction of PARPi Resistance-related Competing Endogenous RNA Network. [PDF]
Curr Genomics, 2022 Objective: Ovarian cancer is the common gynecological malignancy in women. PARP inhibitors (PARPi) have been approved for ovarian cancer treatment. However, the primary and acquired resistance have limited the application of PARPi. The mechanisms underlying remain to be elucidated.
Kong L +5 more
europepmc +3 more sources
Competing endogenous RNA network for esophageal cancer progression. [PDF]
Ann Transl Med, 2021 Esophageal cancer (ESCA) constitutes one of the most common cancers worldwide. The identification of potential biomarkers is important to improving the diagnostic accuracy and treatment efficiency for patients with ESCA. In this study, we aimed to identify biomarkers related to ESCA progression through a comprehensive analysis of long non-coding RNAs ...
Chen S +9 more
europepmc +4 more sources