A competing endogenous RNA network reveals key lncRNAs associated with sepsis [PDF]
Molecular Genetics & Genomic Medicine, 2021 Background This study set out to determine key lncRNAs correlated with sepsis via constructing competing endogenous RNA (ceRNA) network. Methods Three septic patients and three healthy controls were recruited to obtain lncRNA profiles in this current ...
Xuan Guo +6 more
doaj +3 more sources
Pyroptosis-related prognosis model, immunocyte infiltration characterization, and competing endogenous RNA network of glioblastoma [PDF]
BMC Cancer, 2022 Background Glioblastoma (GBM) has a high incidence rate, invasive growth, and easy recurrence, and the current therapeutic effect is less than satisfying. Pyroptosis plays an important role in morbidity and progress of GBM.
Min-Rui Ding +7 more
doaj +2 more sources
Constructing a competing endogenous RNA network for osteoarthritis. [PDF]
Ann Transl Med, 2022 Osteoarthritis (OA) is one of the most common diseases in elderly people; however, the correlation between molecular alterations and the occurrence and progression of OA are still not well understood. We conducted this study to investigate the molecular changes in OA via the competing endogenous ribonucleic acid (ceRNA) network.We downloaded the ...
Hua SL +5 more
europepmc +4 more sources
Identification of a competing endogenous RNA network associated with prognosis of pancreatic adenocarcinoma [PDF]
Cancer Cell International, 2020 Background Emerging evidence suggests that competing endogenous RNAs plays a crucial role in the development and progress of pancreatic adenocarcinoma (PAAD).
Wanqing Weng +8 more
doaj +3 more sources
Construction of PARPi Resistance-related Competing Endogenous RNA Network. [PDF]
Curr Genomics, 2022 Objective: Ovarian cancer is the common gynecological malignancy in women. PARP inhibitors (PARPi) have been approved for ovarian cancer treatment. However, the primary and acquired resistance have limited the application of PARPi. The mechanisms underlying remain to be elucidated.
Kong L +5 more
europepmc +3 more sources
Competing endogenous RNA network for esophageal cancer progression. [PDF]
Ann Transl Med, 2021 Esophageal cancer (ESCA) constitutes one of the most common cancers worldwide. The identification of potential biomarkers is important to improving the diagnostic accuracy and treatment efficiency for patients with ESCA. In this study, we aimed to identify biomarkers related to ESCA progression through a comprehensive analysis of long non-coding RNAs ...
Chen S +9 more
europepmc +4 more sources
Competing Endogenous RNA Networks in Glioma [PDF]
Frontiers in Genetics, 2021 Gliomas are the most common and malignant primary brain tumors. Various hallmarks of glioma, including sustained proliferation, migration, invasion, heterogeneity, radio- and chemo-resistance, contribute to the dismal prognosis of patients with high-grade glioma. Dysregulation of cancer driver genes is a leading cause for these glioma hallmarks.
Liang Cen +9 more
openaire +3 more sources
Integrated Bioinformatic Analysis of Competing Endogenous RNA Network of Choriocarcinoma. [PDF]
Med Sci Monit, 2021 BACKGROUND Numerous studies have demonstrated that noncoding RNAs are involved in choriocarcinoma (CC). The competing endogenous RNA (ceRNA) network plays an important role in the occurrence and development of carcinoma. However, the involvement of the ceRNA network in CC remains unclear.
Tan Q, Tan Z, Liu J, Mo Y, Liu H.
europepmc +4 more sources
Construction and comprehensive analysis of the competing endogenous RNA network in endometrial adenocarcinoma. [PDF]
BMC Genom Data, 2022 Abstract Background: Endometrial carcinoma (EC) is one of the most common gynecological malignant tumors. In this study, we constructed gene co-expression networks to identify key modules and hub genes involved in the pathogenesis of EC. Methods: The RNA profiles of adenocarcinoma and non-adenocarcinoma tissues of patients with EC from The ...
Feng C +7 more
europepmc +5 more sources
Competing Endogenous RNA Networks as Biomarkers in Neurodegenerative Diseases [PDF]
International Journal of Molecular Sciences, 2020 Protein aggregation is classically considered the main cause of neuronal death in neurodegenerative diseases (NDDs). However, increasing evidence suggests that alteration of RNA metabolism is a key factor in the etiopathogenesis of these complex disorders.
Leticia Moreno-García +10 more
openaire +3 more sources