Results 21 to 30 of about 83,602 (280)

Identification of a competing endogenous RNA network associated with prognosis of pancreatic adenocarcinoma [PDF]

Cancer Cell International, 2020
Background Emerging evidence suggests that competing endogenous RNAs plays a crucial role in the development and progress of pancreatic adenocarcinoma (PAAD).
Wanqing Weng, Zhongjing Zhang, Weiguo Huang, Xiangxiang Xu, Boda Wu, Tingbo Ye, Yunfeng Shan, Keqing Shi, Zhuo Lin   +8 more
doaj   +3 more sources

Construction of PARPi Resistance-related Competing Endogenous RNA Network. [PDF]

Curr Genomics, 2022
Objective: Ovarian cancer is the common gynecological malignancy in women. PARP inhibitors (PARPi) have been approved for ovarian cancer treatment. However, the primary and acquired resistance have limited the application of PARPi. The mechanisms underlying remain to be elucidated.
Kong L, Xu J, Yu L, Liu S, Liu Z, Xiang J.   +5 more
europepmc   +3 more sources

Comprehensive Analysis of Competing Endogenous RNA Network Focusing on Long Noncoding RNA Involved in Cirrhotic Hepatocellular Carcinoma [PDF]

Analytical Cellular Pathology, 2021
The role of long noncoding RNAs- (lncRNAs-) associated competing endogenous RNA (ceRNA) in the field of hepatocellular carcinoma (HCC) biology is well established, but the involvement of lncRNAs competing interactions in the progression of liver ...
Yuli Zhang, Dinggui Chen, Miaomiao Yang, Xianfeng Qian, Chunmei Long, Zhongwei Zheng   +5 more
doaj   +2 more sources

Competing endogenous RNA network for esophageal cancer progression. [PDF]

Ann Transl Med, 2021
Esophageal cancer (ESCA) constitutes one of the most common cancers worldwide. The identification of potential biomarkers is important to improving the diagnostic accuracy and treatment efficiency for patients with ESCA. In this study, we aimed to identify biomarkers related to ESCA progression through a comprehensive analysis of long non-coding RNAs ...
Chen S, Ju G, Gu J, Shi M, Wang Y, Wu X, Wang Q, Zheng L, Xiao T, Fan Y.   +9 more
europepmc   +4 more sources

Integrated analysis of the lncRNA-associated competing endogenous RNA network in salt sensitivity of blood pressure. [PDF]

Heliyon, 2023
Accumulating evidence showed that competing endogenous RNA (ceRNA) mechanism plays a pivotal role in salt sensitivity of blood pressure (SSBP). We constructed a ceRNA network based on SSBP-related differently expressed lncRNAs (2), mRNAs (73) and miRNAs (
Peng W, Xie Y, Xia J, Qi H, Liu K, Li B, Zhang F, Wen F, Zhang L.   +8 more
europepmc   +2 more sources

Competing Endogenous RNA Networks in Glioma [PDF]

Frontiers in Genetics, 2021
Gliomas are the most common and malignant primary brain tumors. Various hallmarks of glioma, including sustained proliferation, migration, invasion, heterogeneity, radio- and chemo-resistance, contribute to the dismal prognosis of patients with high-grade glioma. Dysregulation of cancer driver genes is a leading cause for these glioma hallmarks.
Liang Cen, Liang Cen, Ruochen Liu, Ruochen Liu, Wei Liu, Wei Liu, Qianqian Li, Hongjuan Cui, Hongjuan Cui, Hongjuan Cui   +9 more
openaire   +3 more sources

Integrated Bioinformatic Analysis of Competing Endogenous RNA Network of Choriocarcinoma. [PDF]

Med Sci Monit, 2021
BACKGROUND Numerous studies have demonstrated that noncoding RNAs are involved in choriocarcinoma (CC). The competing endogenous RNA (ceRNA) network plays an important role in the occurrence and development of carcinoma. However, the involvement of the ceRNA network in CC remains unclear.
Tan Q, Tan Z, Liu J, Mo Y, Liu H.
europepmc   +4 more sources

Construction and comprehensive analysis of the competing endogenous RNA network in endometrial adenocarcinoma. [PDF]

BMC Genom Data, 2022
Abstract Background: Endometrial carcinoma (EC) is one of the most common gynecological malignant tumors. In this study, we constructed gene co-expression networks to identify key modules and hub genes involved in the pathogenesis of EC. Methods: The RNA profiles of adenocarcinoma and non-adenocarcinoma tissues of patients with EC from The ...
Feng C, Cui L, Jin Z, Sun L, Wang X, Chi X, Sun Q, Lian S.   +7 more
europepmc   +5 more sources

The competing endogenous RNA network for the 5 miRNAs with maximum interactions. [PDF]

, 2022
(A) lncRNA-miRNA-mRNA competing endogenous RNA network. Multiple colours represent upregulation and downregulation of miRNAs, lncRNAs and mRNAs in the case sample compared with the control. Vee, triangle, and ellipse indicate DE-miRNAs, lncRNAs and mRNAs,
Na Li (6550), Pengke He (14279214), Mukaram Amatjan (14279211), Hengxiu Yan (14279220), Meiwei Wu (14279217), Xiaoni Shao (14279223)   +5 more
core   +1 more source

Competing Endogenous RNA Networks as Biomarkers in Neurodegenerative Diseases [PDF]

International Journal of Molecular Sciences, 2020
Protein aggregation is classically considered the main cause of neuronal death in neurodegenerative diseases (NDDs). However, increasing evidence suggests that alteration of RNA metabolism is a key factor in the etiopathogenesis of these complex disorders.
Leticia Moreno-García, Tresa López-Royo, Ana Cristina Calvo, Janne Markus Toivonen, Miriam de la Torre, Laura Moreno-Martínez, Nora Molina, Paula Aparicio, Pilar Zaragoza, Raquel Manzano, Rosario Osta   +10 more
openaire   +3 more sources