Competing Endogenous RNA Networks in Glioma [PDF]
Frontiers in Genetics, 2021 Gliomas are the most common and malignant primary brain tumors. Various hallmarks of glioma, including sustained proliferation, migration, invasion, heterogeneity, radio- and chemo-resistance, contribute to the dismal prognosis of patients with high-grade glioma. Dysregulation of cancer driver genes is a leading cause for these glioma hallmarks.
Liang Cen +9 more
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Integrated Bioinformatic Analysis of Competing Endogenous RNA Network of Choriocarcinoma. [PDF]
Med Sci Monit, 2021 BACKGROUND Numerous studies have demonstrated that noncoding RNAs are involved in choriocarcinoma (CC). The competing endogenous RNA (ceRNA) network plays an important role in the occurrence and development of carcinoma. However, the involvement of the ceRNA network in CC remains unclear.
Tan Q, Tan Z, Liu J, Mo Y, Liu H.
europepmc +4 more sources
MiR-96 induced non-small-cell lung cancer progression through competing endogenous RNA network and affecting EGFR signaling pathway [PDF]
Iranian Journal of Basic Medical Sciences, 2019 Objective(s): Non-small cell lung cancer (NSCLC) has become a serious global health problem in the 21st century, and tumor proliferation and metastasis are the leading causes of death in patients with lung cancer.
Hao Ding +5 more
doaj +1 more source
A Novel Immune-Related Competing Endogenous RNA Network Predicts Prognosis of Acute Myeloid Leukemia
Frontiers in Oncology, 2020 BackgroundAcute myeloid leukemia (AML) is a genetically, biologically and clinically heterogeneous hematopoietic malignancy that is highly dependent on the bone marrow (BM) microenvironment.
Shujuan Wang +7 more
doaj +1 more source
Respiratory Research, 2020 Background Asthma is a heterogeneous disease characterized by chronic airway inflammation. Long non-coding RNA can act as competing endogenous RNA to mRNA, and play significant role in many diseases.
Yifang Liao +5 more
doaj +1 more source
Comprehensive analysis of an lncRNA-miRNA-mRNA competing endogenous RNA network in pulpitis [PDF]
PeerJ, 2019 Background Pulpitis is a common inflammatory disease that affects dental pulp. It is important to understand the molecular signals of inflammation and repair associated with this process. Increasing evidence has revealed that long noncoding RNAs (lncRNAs)
Fangcao Lei, Han Zhang, Xiaoli Xie
doaj +2 more sources
ATM deficiency results in accumulation of DNA-Topoisomerase I covalent intermediates in neural cells [PDF]
, 2013 Accumulation of peptide-linked DNA breaks contributes to neurodegeration in humans. This is typified by defects in tyrosyl DNA phosphodiesterase 1 (TDP1) and human hereditary ataxia.
Alagoz, Meryem +3 more
core +14 more sources
Analysis of the lncRNA-Associated Competing Endogenous RNA (ceRNA) Network for Tendinopathy
Genetics Research, 2022 Background. We aimed to construct the lncRNA-associated competing endogenous RNA (ceRNA) network and distinguish feature lncRNAs associated with tendinopathy. Methods.
Bing-Zhe Huang +4 more
doaj +1 more source
Interferon-alpha competing endogenous RNA network antagonizes microRNA-1270 [PDF]
Cellular and Molecular Life Sciences, 2015 A new form of circuitry for gene regulation has been identified in which RNAs can crosstalk by competing for shared microRNAs (miRNAs). Such competing endogenous RNAs (ceRNAs) form a network via shared miRNA response elements (MREs) to antagonize miRNA function.
Kimura, Tominori +4 more
openaire +2 more sources
The Role of Long Noncoding RNAs in Endometriosis Progression
Frontiers in Bioscience-Landmark, 2023 Endometriosis (EMs) is a common gynecological disease with an increasing incidence in recent years. Because of the lack of specific molecular biological indicators in clinical practice, diagnosis is often delayed and the quality of life of patients is ...
Yong Liu +5 more
doaj +1 more source