Results 21 to 30 of about 81,616 (246)

A novel ceRNA-immunoregulatory axis based on immune cell infiltration in ulcerative colitis-associated colorectal carcinoma by integrated weighted gene co-expression network analysis

open access: yesBMC Gastroenterology, 2022
Background Patients with ulcerative colitis are at an increased risk of developing colorectal cancer with a prolonged disease course. Many studies have shown that alterations in the immune microenvironment play a key role in ulcerative colitis-associated
Shi Yin   +8 more
doaj   +1 more source

Effect of SARS-CoV-2 infection on host competing endogenous RNA and miRNA network [PDF]

open access: yesPeerJ, 2021
Competing endogenous RNAs (ceRNA) play a crucial role in cell functions. Computational methods that provide large-scale analysis of the interactions between miRNAs and their competitive targets can contribute to the understanding of ceRNA regulations and
Selcen Ari Yuka, Alper Yilmaz
doaj   +2 more sources

MiR-96 induced non-small-cell lung cancer progression through competing endogenous RNA network and affecting EGFR signaling pathway [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2019
Objective(s): Non-small cell lung cancer (NSCLC) has become a serious global health problem in the 21st century, and tumor proliferation and metastasis are the leading causes of death in patients  with lung cancer.
Hao Ding   +5 more
doaj   +1 more source

A Novel Immune-Related Competing Endogenous RNA Network Predicts Prognosis of Acute Myeloid Leukemia

open access: yesFrontiers in Oncology, 2020
BackgroundAcute myeloid leukemia (AML) is a genetically, biologically and clinically heterogeneous hematopoietic malignancy that is highly dependent on the bone marrow (BM) microenvironment.
Shujuan Wang   +7 more
doaj   +1 more source

Construction of asthma related competing endogenous RNA network revealed novel long non-coding RNAs and potential new drugs

open access: yesRespiratory Research, 2020
Background Asthma is a heterogeneous disease characterized by chronic airway inflammation. Long non-coding RNA can act as competing endogenous RNA to mRNA, and play significant role in many diseases.
Yifang Liao   +5 more
doaj   +1 more source

Comprehensive analysis of an lncRNA-miRNA-mRNA competing endogenous RNA network in pulpitis [PDF]

open access: yesPeerJ, 2019
Background Pulpitis is a common inflammatory disease that affects dental pulp. It is important to understand the molecular signals of inflammation and repair associated with this process. Increasing evidence has revealed that long noncoding RNAs (lncRNAs)
Fangcao Lei, Han Zhang, Xiaoli Xie
doaj   +2 more sources

The Role of Long Noncoding RNAs in Endometriosis Progression

open access: yesFrontiers in Bioscience-Landmark, 2023
Endometriosis (EMs) is a common gynecological disease with an increasing incidence in recent years. Because of the lack of specific molecular biological indicators in clinical practice, diagnosis is often delayed and the quality of life of patients is ...
Yong Liu   +5 more
doaj   +1 more source

Construction of competing endogenous RNA interaction network as prognostic markers in metastatic melanoma [PDF]

open access: yesPeerJ, 2021
Malignant melanoma (MM) is a malignant tumor originating from melanocytes, with high aggressiveness, high metastasis and extremely poor prognosis.
Zan He   +4 more
doaj   +2 more sources

Bioinformatics analysis of long non-coding RNA-associated competing endogenous RNA network in schizophrenia

open access: yesScientific Reports, 2021
Schizophrenia (SCZ) is a serious psychiatric condition with a 1% lifetime risk. SCZ is one of the top ten global causes of disabilities. Despite numerous attempts to understand the function of genetic factors in SCZ development, genetic components in SCZ
Hani Sabaie   +7 more
doaj   +1 more source

Analysis of circular RNA‑associated competing endogenous RNA network in breast cancer

open access: yesOncology Letters, 2020
As the most common type of cancer in female patients, the morbidity and mortality rates of breast cancer (BC) are high, and its incidence is gradually increasing worldwide. However, the underlying molecular and genetic mechanisms involved in the etiopathogenesis of BC remain unclear.
Wang, Xuekang   +7 more
openaire   +3 more sources

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