Results 31 to 40 of about 88,679 (239)
Modelling Competing Endogenous RNA Networks
PLoS ONE, 2013 28 pages, 9 pdf ...
Bosia C +3 more
openaire +6 more sources
Cancer Cell International, 2019 Background It is becoming increasingly clear that cancers can rarely be ascribed to just one or a few genomic variations. Genes generally do not function alone, but in groups that function as “networks”. This study aimed to develop a competing endogenous
Min-Er Zhong +5 more
doaj +1 more source
Circular RNAs and competing endogenous RNA (ceRNA) networks
Translational Cancer Research, 2018 In recent years, advances in bioinformatics approaches have allowed a systematic characterization of circular RNAs (circRNAs) across a variety of cell types. Demonstration of cell type specificity, regulated expression, and conservation between species all suggest that circRNAs have functional importance.
Apratim, Mitra +2 more
openaire +2 more sources
Frontiers in Genetics, 2022 Astrocytes are widely distributed in the central nervous system and play an essential role in the function of neuronal cells. Associations between astrocytes and Alzheimer’s disease (AD) have been noted, and recent work has implicated circular RNA ...
Yuxin Deng +10 more
doaj +1 more source
Genome‐wide identification of a competing endogenous RNA network in cholangiocarcinoma [PDF]
Journal of Cellular Biochemistry, 2019 AbstractCholangiocarcinoma (CCA) is the second widespread liver tumor with relatively poor survival. Increasing evidence in recent studies showed long noncoding RNAs (lncRNAs) exert a crucial impact on the development and progression of CCA based on the mechanism of competing endogenous RNAs (ceRNAs). However, functional roles and regulatory mechanisms
Ganxun Li +4 more
openaire +2 more sources
Identification of Circular RNA-Based Immunomodulatory Networks in Colorectal Cancer
Frontiers in Oncology, 2022 BackgroundCircular RNAs (circRNAs) have been recently proposed as hub molecules in various diseases, especially in tumours. We found that circRNAs derived from ribonuclease P RNA component H1 (RPPH1) were highly expressed in colorectal cancer (CRC ...
Zongfeng Feng +29 more
doaj +1 more source
Competing Endogenous RNA Network Analysis Reveals Pivotal ceRNAs in Adrenocortical Carcinoma
Frontiers in Endocrinology, 2019 Objective: To construct ceRNA network and identify pivotal competing endogenous RNAs (ceRNAs) in adrenocortical carcinoma (ACC) using ceRNA network analysis.Methods: The RNA sequencing expression data of 77 ACCs in TCGA were obtained from GEPIA.
Weiwei Liang, Fangfang Sun
doaj +1 more source
Competing endogenous RNA regulatory network in papillary thyroid carcinoma
Molecular Medicine Reports, 2018 The present study aimed to screen all types of RNAs involved in the development of papillary thyroid carcinoma (PTC). RNA‑sequencing data of PTC and normal samples were used for screening differentially expressed (DE) microRNAs (DE‑miRNAs), long non‑coding RNAs (DE‑lncRNAs) and genes (DEGs).
Chen, Shouhua +4 more
openaire +3 more sources
Development of an immunogenomic landscape for the competing endogenous RNAs network of peri-implantitis [PDF]
BMC Medical Genetics, 2020 Abstract Background Peri-implantitis is an inflammation that occurs around the implant, resulting in varying degrees of inflammatory damage to the soft and hard tissues. The characteristic criterion is the loss of the supporting bone in an inflammatory environment.
Yang Li +5 more
openaire +3 more sources
The characteristics of circRNA as competing endogenous RNA in pathogenesis of acute myeloid leukemia
BMC Cancer, 2021 Background As one of the novel molecules, circRNA has been identified closely involved in the pathogenesis of many diseases. However, the function of circRNA in acute myeloid leukemia (AML) still remains unknown.
Siyuan Zhang
doaj +1 more source