Results 31 to 40 of about 5,884,744 (246)

The Role of Long Noncoding RNAs in Endometriosis Progression

Frontiers in Bioscience-Landmark, 2023
Endometriosis (EMs) is a common gynecological disease with an increasing incidence in recent years. Because of the lack of specific molecular biological indicators in clinical practice, diagnosis is often delayed and the quality of life of patients is ...
Yong Liu, Wensi Zhang, Lingge Jin, Jian Ren, Zhaohui Liu, Dan Lu   +5 more
doaj   +1 more source

Bioinformatics analysis of long non-coding RNA-associated competing endogenous RNA network in schizophrenia

Scientific Reports, 2021
Schizophrenia (SCZ) is a serious psychiatric condition with a 1% lifetime risk. SCZ is one of the top ten global causes of disabilities. Despite numerous attempts to understand the function of genetic factors in SCZ development, genetic components in SCZ
Hani Sabaie, Madiheh Mazaheri Moghaddam, Marziyeh Mazaheri Moghaddam, Noora Karim Ahangar, Mohammad Reza Asadi, Bashdar Mahmud Hussen, Mohammad Taheri, Maryam Rezazadeh   +7 more
doaj   +1 more source

Long Noncoding Competing Endogenous RNA Networks in Pancreatic Cancer

Frontiers in Oncology, 2021
Pancreatic cancer (PC) is a highly malignant disease characterized by insidious onset, rapid progress, and poor therapeutic effects. The molecular mechanisms associated with PC initiation and progression are largely insufficient, hampering the ...
Guangbing Xiong, Shutao Pan, Jikuan Jin, Xiaoxiang Wang, Ruizhi He, Feng Peng, Xu Li, Min Wang, Jianwei Zheng, Feng Zhu, Renyi Qin   +10 more
doaj   +1 more source

The top 15 nodes in the competing endogenous RNA (ceRNA) regulatory network in the blue module and the turquoise module.

, 2022
The top 15 nodes in the competing endogenous RNA (ceRNA) regulatory network in the blue module and the turquoise module.
Ren-Dong Xiao (12878506), Yu Wang (12152), Quan Du (58889), Rong-Gang Luo (12878509), Jin-Bao Xie (12878512), Zu-Dong Su (12878515)   +5 more
core   +1 more source

LncRNA H19 regulates PI3K–Akt signal pathway by functioning as a ceRNA and predicts poor prognosis in colorectal cancer: integrative analysis of dysregulated ncRNA-associated ceRNA network

Cancer Cell International, 2019
Background It is becoming increasingly clear that cancers can rarely be ascribed to just one or a few genomic variations. Genes generally do not function alone, but in groups that function as “networks”. This study aimed to develop a competing endogenous
Min-Er Zhong, Yanyu Chen, Guannan Zhang, Lai Xu, Wei Ge, Bin Wu   +5 more
doaj   +1 more source

High-Throughput Sequencing to Investigate lncRNA-circRNA-miRNA-mRNA Networks Underlying the Effects of Beta-Amyloid Peptide and Senescence on Astrocytes

Frontiers in Genetics, 2022
Astrocytes are widely distributed in the central nervous system and play an essential role in the function of neuronal cells. Associations between astrocytes and Alzheimer’s disease (AD) have been noted, and recent work has implicated circular RNA ...
Yuxin Deng, Yuxin Deng, Hui Song, Yan Xiao, Yi Zhao, Liangzao Chu, Jiuyang Ding, Xiangchun Shen, Xiaolan Qi, Xiaolan Qi, Xiaolan Qi   +10 more
doaj   +1 more source

Identification of Circular RNA-Based Immunomodulatory Networks in Colorectal Cancer

Frontiers in Oncology, 2022
BackgroundCircular RNAs (circRNAs) have been recently proposed as hub molecules in various diseases, especially in tumours. We found that circRNAs derived from ribonuclease P RNA component H1 (RPPH1) were highly expressed in colorectal cancer (CRC ...
Zongfeng Feng, Zongfeng Feng, Zongfeng Feng, Leyan Li, Leyan Li, Leyan Li, Yi Tu, Xufeng Shu, Xufeng Shu, Xufeng Shu, Yang Zhang, Yang Zhang, Yang Zhang, Qingwen Zeng, Qingwen Zeng, Qingwen Zeng, Lianghua Luo, Lianghua Luo, Lianghua Luo, Ahao Wu, Ahao Wu, Wenzheng Chen, Wenzheng Chen, Wenzheng Chen, Yi Cao, Yi Cao, Yi Cao, Zhengrong Li, Zhengrong Li, Zhengrong Li   +29 more
doaj   +1 more source

Competing endogenous RNA crosstalk at system level [PDF]

, 2019
microRNAs (miRNAs) regulate gene expression at post-transcriptional level by repressing target RNA molecules. Competition to bind miRNAs tends in turn to correlate their targets, establishing effective RNA-RNA interactions that can influence expression ...
Enzo Marinari, Enzo Marinari (156377), Andrea De Martino, Marinari E., Miotto M., Mattia Miotto (7645754), Andrea De Martino (150977), Mattia Miotto, De Martino A.   +8 more
core   +1 more source

The characteristics of circRNA as competing endogenous RNA in pathogenesis of acute myeloid leukemia

BMC Cancer, 2021
Background As one of the novel molecules, circRNA has been identified closely involved in the pathogenesis of many diseases. However, the function of circRNA in acute myeloid leukemia (AML) still remains unknown.
Siyuan Zhang
doaj   +1 more source

A small RNA response at DNA ends in Drosophila [PDF]

, 2012
Small RNAs have been implicated in numerous cellular processes, including effects on chromatin structure and the repression of transposons. We describe the generation of a small RNA response at DNA ends in Drosophila that is analogous to the recently ...
Förstemann, Klaus, Böttcher, Romy, Michalik, Katharina M.   +2 more
core   +1 more source