Results 51 to 60 of about 83,602 (280)

Table6_A Novel Competing Endogenous RNA Network Associated With the Pathogenesis of Graves’ Ophthalmopathy.XLSX [PDF]

, 2021
Background: Growing evidence has recently revealed the characteristics of long noncoding (lncRNA)/circular RNA (circRNA)-microRNA (miRNA)-mRNA networks in numerous human diseases. However, a scientific lncRNA/circRNA-miRNA-mRNA network related to Graves’
Ruili Wei (848963), Zifan Yue (11837303), Pei Mou (814158), Sainan Chen (3204084), Fei Tong (1729285)   +4 more
core   +1 more source

Table4_A Novel Competing Endogenous RNA Network Associated With the Pathogenesis of Graves’ Ophthalmopathy.XLSX [PDF]

, 2021
Background: Growing evidence has recently revealed the characteristics of long noncoding (lncRNA)/circular RNA (circRNA)-microRNA (miRNA)-mRNA networks in numerous human diseases. However, a scientific lncRNA/circRNA-miRNA-mRNA network related to Graves’
Ruili Wei (848963), Zifan Yue (11837303), Pei Mou (814158), Sainan Chen (3204084), Fei Tong (1729285)   +4 more
core   +1 more source

LncRNA H19 regulates PI3K–Akt signal pathway by functioning as a ceRNA and predicts poor prognosis in colorectal cancer: integrative analysis of dysregulated ncRNA-associated ceRNA network

Cancer Cell International, 2019
Background It is becoming increasingly clear that cancers can rarely be ascribed to just one or a few genomic variations. Genes generally do not function alone, but in groups that function as “networks”. This study aimed to develop a competing endogenous
Min-Er Zhong, Yanyu Chen, Guannan Zhang, Lai Xu, Wei Ge, Bin Wu   +5 more
doaj   +1 more source

Circular RNAs and competing endogenous RNA (ceRNA) networks

Translational Cancer Research, 2018
In recent years, advances in bioinformatics approaches have allowed a systematic characterization of circular RNAs (circRNAs) across a variety of cell types. Demonstration of cell type specificity, regulated expression, and conservation between species all suggest that circRNAs have functional importance.
Apratim, Mitra, Karl, Pfeifer, Ki-Sun, Park   +2 more
openaire   +2 more sources

Competing endogenous RNA networks and gastric cancer

World Journal of Gastroenterology, 2015
Recent studies have showed that RNAs regulate each other with microRNA (miRNA) response elements (MREs) and this mechanism is known as "competing endogenous RNA (ceRNA)" hypothesis. Long non-coding RNAs (lncRNAs) are supposed to play important roles in cancer.
Lei-Lei, Guo, Chun-Hua, Song, Peng, Wang, Li-Ping, Dai, Jian-Ying, Zhang, Kai-Juan, Wang   +5 more
openaire   +2 more sources

Genome‐wide identification of a competing endogenous RNA network in cholangiocarcinoma [PDF]

Journal of Cellular Biochemistry, 2019
AbstractCholangiocarcinoma (CCA) is the second widespread liver tumor with relatively poor survival. Increasing evidence in recent studies showed long noncoding RNAs (lncRNAs) exert a crucial impact on the development and progression of CCA based on the mechanism of competing endogenous RNAs (ceRNAs). However, functional roles and regulatory mechanisms
Ganxun Li, Tongtong Liu, Bixiang Zhang, Weixun Chen, Zeyang Ding   +4 more
openaire   +2 more sources

The expression profiles of circular RNAs and competing endogenous RNA networks in intrahepatic cholangiocarcinoma

Frontiers in Cell and Developmental Biology, 2022
Introduction: Intrahepatic cholangiocarcinoma (iCCA) is a heterogeneous entity with diverse etiologies, morphologies, and clinical outcomes, but our knowledge of its epidemiology and carcinogenesis is very limited.Materials and methods: The expression patterns of circRNAs were explored in iCCA tissues and corresponding adjacent normal ones, denoted by (
Zi Liang, Zi Liang, Liyan Liu, Xinyi Guo, Xia Wu, Yun-Li Yu, Ziyang Yu, Xiaolong Hu, Xing Zhang, Ji Wang   +9 more
openaire   +3 more sources

Competing endogenous RNA crosstalk at system level [PDF]

, 2019
microRNAs (miRNAs) regulate gene expression at post-transcriptional level by repressing target RNA molecules. Competition to bind miRNAs tends in turn to correlate their targets, establishing effective RNA-RNA interactions that can influence expression ...
Enzo Marinari, Enzo Marinari (156377), Andrea De Martino, Marinari E., Miotto M., Mattia Miotto (7645754), Andrea De Martino (150977), Mattia Miotto, De Martino A.   +8 more
core   +1 more source

Image3_A Novel Competing Endogenous RNA Network Associated With the Pathogenesis of Graves’ Ophthalmopathy.TIF [PDF]

, 2021
Background: Growing evidence has recently revealed the characteristics of long noncoding (lncRNA)/circular RNA (circRNA)-microRNA (miRNA)-mRNA networks in numerous human diseases. However, a scientific lncRNA/circRNA-miRNA-mRNA network related to Graves’
Ruili Wei (848963), Zifan Yue (11837303), Pei Mou (814158), Sainan Chen (3204084), Fei Tong (1729285)   +4 more
core   +1 more source

High-Throughput Sequencing to Investigate lncRNA-circRNA-miRNA-mRNA Networks Underlying the Effects of Beta-Amyloid Peptide and Senescence on Astrocytes

Frontiers in Genetics, 2022
Astrocytes are widely distributed in the central nervous system and play an essential role in the function of neuronal cells. Associations between astrocytes and Alzheimer’s disease (AD) have been noted, and recent work has implicated circular RNA ...
Yuxin Deng, Yuxin Deng, Hui Song, Yan Xiao, Yi Zhao, Liangzao Chu, Jiuyang Ding, Xiangchun Shen, Xiaolan Qi, Xiaolan Qi, Xiaolan Qi   +10 more
doaj   +1 more source