Results 41 to 50 of about 56,767 (239)

Kinetic Modelling of Competition and Depletion of Shared miRNAs by Competing Endogenous RNAs [PDF]

, 2019
Non-conding RNAs play a key role in the post-transcriptional regulation of mRNA translation and turnover in eukaryotes. miRNAs, in particular, interact with their target RNAs through protein-mediated, sequence-specific binding, giving rise to extended and highly heterogeneous miRNA-RNA interaction networks.
Martirosyan, Araks, Del Giudice, Marco, ENRICO BENA, CHIARA, Pagnani, Andrea, Bosia, Carla, De Martino, Andrea   +5 more
openaire   +4 more sources

Comprehensive identification and characterization of lncRNAs and circRNAs reveal potential brown planthopper-responsive ceRNA networks in rice

Frontiers in Plant Science, 2023
Brown planthopper (Nilaparvata lugens Stål, BPH) is one of the most destructive pests of rice. Non-coding RNA plays an important regulatory role in various biological processes.
Yan Wu, Yan Wu, Wenjun Zha, Wenjun Zha, Dongfeng Qiu, Jianping Guo, Gang Liu, Changyan Li, Bian Wu, Sanhe Li, Junxiao Chen, Liang Hu, Shaojie Shi, Lei Zhou, Lei Zhou, Zaijun Zhang, Bo Du, Aiqing You, Aiqing You   +18 more
doaj   +1 more source

Non‐coding RNA Identification in Osteonecrosis of the Femoral Head Using Competitive Endogenous RNA Network Analysis

Orthopaedic Surgery, 2021
Objective To investigate the regulatory network of long non‐coding RNA (lncRNA) as competing endogenous RNAs (ceRNAs) in osteonecrosis of the femoral head (ONFH).
Ning Han, Zengchun Li
doaj   +1 more source

Construction of a Competitive Endogenous RNA Network in Uterine Corpus Endometrial Carcinoma [PDF]

Medical Science Monitor, 2019
BACKGROUND Long non-coding RNAs (lncRNAs) affect post-transcriptional regulation by interfering with microRNAs (miRNAs), and by acting as competitive endogenous RNAs (ceRNAs). The roles and mechanisms of lncRNAs as ceRNAs in the progression and prognosis of uterine corpus endometrial carcinoma are not well understood.
Ouyang, Dong, Li, Ruyi, Li, Yaxian, Zhu, Xueqiong   +3 more
openaire   +2 more sources

Bioinformatics Analysis of circRNA Expression and Construction of “circRNA-miRNA-mRNA” Competing Endogenous RNAs Networks in Bipolar Disorder Patients

Frontiers in Genetics, 2021
Bipolar disorder (BD) is a severe mood disorder disease in China, and its underlying pathogenesis remains unknown. Circular RNAs (circRNAs) have been reported to play a key role in mental disorders and can be used as competitive endogenous RNAs (ceRNAs).
Yonghui Fu, Wenfeng He, Chaoxiong Zhou, Xia Fu, Qigen Wan, Ling He, Bo Wei   +6 more
doaj   +1 more source

HMGA1pseudogenes as candidate proto-oncogenic competitive endogenous RNAs

Oncotarget, 2014
The High Mobility Group A (HMGA) are nuclear proteins that participate in the organization of nucleoprotein complexes involved in chromatin structure, replication and gene transcription. HMGA overexpression is a feature of human cancer and plays a causal role in cell transformation.
Esposito F, de Martino M, Petti MG, Forzati F, Tornincasa M, Federico A, Arra C, Pierantoni GM, Fusco A   +8 more
openaire   +6 more sources

Long Non-Coding RNA C1QTNF1 Antisense RNA 1 Upregulates Hexokinase 2 by Sponging microRNA-484 to Promote the Malignancy of Colorectal Cancer [Retraction]

Cancer Management and Research, 2021
Jin S, Liu Y, Wang W, Li Z. Cancer Manag Res. 2020;12: 12053–12066. The Editor and Publisher of Cancer Management and Research wish to retract the published paper. Concerns were raised over the flow cytometry data presented in the article.
Jin S, Liu Y, Wang W, Li Z
doaj  

The Construction and Comprehensive Analysis of a ceRNA Immunoregulatory Network and Tissue-Infiltrating Immune Cells in Atrial Fibrillation

International Journal of General Medicine, 2021
Xing Liu,1 Guoqiang Zhong,2 Wenbin Li,1 Yiqian Zeng,3 Mingxing Wu1 1Department of Cardiology, Xiangtan Central Hospital, Xiangtan, Hunan, People’s Republic of China; 2Department of Cardiology, Guangxi Cardiovascular Institute, The First Affiliated ...
Liu X, Zhong G, Li W, Zeng Y, Wu M
doaj  

Predicting lymph node metastasis and prognosis of individual cancer patients based on miRNA-mediated RNA interactions

BMC Medical Genomics, 2022
Background Lymph node metastasis is usually detected based on the images obtained from clinical examinations. Detecting lymph node metastasis from clinical examinations is a direct way of diagnosing metastasis, but the diagnosis is done after lymph node ...
Shulei Ren, Wook Lee, Kyungsook Han
doaj   +1 more source

Competitive endogenous RNA is an intrinsic component of EMT regulatory circuits and modulates EMT [PDF]

Nature Communications, 2019
AbstractThe competitive endogenous RNA (ceRNA) hypothesis suggests an intrinsic mechanism to regulate biological processes. However, whether the dynamic changes of ceRNAs can modulate miRNA activities remains controversial. Here, we examine the dynamics of ceRNAs during TGF-β-induced epithelial-to-mesenchymal transition (EMT).
Yuwei Liu, Mengzhu Xue, Shaowei Du, Wanwan Feng, Ke Zhang, Liwen Zhang, Haiyue Liu, Guoyi Jia, Lingshuang Wu, Xin Hu, Luonan Chen, Peng Wang   +11 more
openaire   +3 more sources