Comprehensive analysis of competitive endogenous RNA network in colorectal cancer [PDF]
Translational Cancer Research, 2020 Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. Growing evidence supports a role for noncoding RNAs (ncRNAs) in CRC. In particular, they form competitive endogenous RNA (ceRNA) networks involved in the regulation of mRNA expression.
Zhang, Meng-Yi, Guo, Bin-Han
openaire +2 more sources
Role of competitive endogenous RNA networks in the pathogenesis of coronary artery disease [PDF]
Annals of Translational Medicine, 2021 The present study aimed to construct a network of competitive endogenous RNAs (ceRNAs) related to the pathogenesis of coronary artery disease (CAD), to provide a novel rationale for CAD treatment.Bioinformatics methods were applied to screen for differentially expressed long non-coding RNAs (DElncRNAs), microRNAs (DEmiRNAs), and mRNAs (DEmRNAs) from ...
Zuo, Jiebin +4 more
openaire +2 more sources
Integrated Analysis of ceRNA Network to Reveal Potential Prognostic Biomarkers for Glioblastoma
Frontiers in Genetics, 2022 Glioblastoma (GBM), originating in the brain, is a universally aggressive malignant tumor with a particularly poor prognosis. Therefore, insight into the critical role of underlying genetic mechanisms is essential to developing new therapeutic approaches.
Ruifei Liu +8 more
doaj +1 more source
BMC Cancer, 2020 Background Human skin cutaneous melanoma is the most common and dangerous skin tumour, but its pathogenesis is still unclear. Although some progress has been made in genetic research, no molecular indicators related to the treatment and prognosis of ...
Junyou Zhu +9 more
doaj +1 more source
Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism [PDF]
, 2010 For a long time it has been assumed that the decay of RNA in eukaryotes is mainly carried out by exoribonucleases, which is in contrast to bacteria, where endoribonucleases are well documented to initiate RNA degradation.
Tomecki, Rafał, Dziembowski, Andrzej
core +3 more sources
Endogenous double-stranded RNA [PDF]
, 2021 \ua9 2021 by the authors. Licensee MDPI, Basel, Switzerland. The birth of long non-coding RNAs (lncRNAs) is closely associated with the presence and activation of repetitive elements in the genome.
Shaymaa Sadeq +7 more
core +1 more source
Whole transcriptome sequencing identifies a competitive endogenous RNA network that regulates the immunity of bladder cancer [PDF]
HeliyonZhiqiang Dong +2 more
exaly +2 more sources
Identification of competitive endogenous RNAs network in breast cancer [PDF]
Cancer Medicine, 2019 AbstractBackgroundMiRNAs can regulate gene expression directly or indirectly, and long noncoding RNAs as competing endogenous RNA (ceRNAs) can bind to miRNAs competitively and affect mRNA expression. The ceRNA network is still unclear in breast cancer.
Xiaojin Wang +7 more
openaire +3 more sources
Competitive endogenous network of circRNA, lncRNA, and miRNA in osteosarcoma chemoresistance
European Journal of Medical Research, 2023 Osteosarcoma is the most prevalent and fatal type of bone tumor. Despite advancements in the treatment of other cancers, overall survival rates for patients with osteosarcoma have stagnated over the past four decades Multiple-drug resistance—the capacity
Shuang Qin +3 more
doaj +1 more source
Circular RNA expression and the competitive endogenous RNA network in pathological, age-related macular degeneration events: A cross-platform normalization study [PDF]
Journal of Biomedical Research, 2023 Sun R +9 more
exaly +2 more sources